Why doesn't finasteride save minoxidil induced hairs?

TravisB

Established Member
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7
It makes no sense at all.

If minoxidil basically prevents DHT attacked hairs from dying, then why after the culprit (DHT) is removed by finasteride, and minoxidil is dropped, they die anyway?
 

Lance

New Member
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4
Minoxidil and Proscar/Finasteride work in two completely separate ways. Minoxidil doesn't block DHT, it simply increases the blood flow to your hair follicles (I believe it was originally used as a type of heart medication when it was discovered that it could also help in growing back/keeping hair). Where as Proscar/Finasteride, which was originally used as prostate medication, actually blocks DHT.

From my understanding, some cases of baldness are simply about the hair follicles not getting a sufficient amount of blood... so increasing the blood flow to the hair follicles is what's needed in those situations (which is why some people have good results with simply using minoxidil). However in most cases baldness is a DHT issue (or possibly a combination of both).

It could be that your situation is a little bit from column A and a little bit from column B. So while the finasteride is blocking the DHT, your follicles still might not be getting enough blood flow without help from the Minoxidil. So either way, increased blood flow to the hair follicles is always a good thing.
 

talmoode

Experienced Member
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16
Minoxidil and Proscar/Finasteride work in two completely separate ways. Minoxidil doesn't block DHT, it simply increases the blood flow to your hair follicles (I believe it was originally used as a type of heart medication when it was discovered that it could also help in growing back/keeping hair). Where as Proscar/Finasteride, which was originally used as prostate medication, actually blocks DHT.

From my understanding, some cases of baldness are simply about the hair follicles not getting a sufficient amount of blood... so increasing the blood flow to the hair follicles is what's needed in those situations (which is why some people have good results with simply using minoxidil). However in most cases baldness is a DHT issue (or possibly a combination of both).

It could be that your situation is a little bit from column A and a little bit from column B. So while the finasteride is blocking the DHT, your follicles still might not be getting enough blood flow without help from the Minoxidil. So either way, increased blood flow to the hair follicles is always a good thing.

Just what I wanted to konw! thank you for the explanation!
 

Baldie101

Established Member
Reaction score
7
Minoxidil and Proscar/Finasteride work in two completely separate ways. Minoxidil doesn't block DHT, it simply increases the blood flow to your hair follicles (I believe it was originally used as a type of heart medication when it was discovered that it could also help in growing back/keeping hair). Where as Proscar/Finasteride, which was originally used as prostate medication, actually blocks DHT.

From my understanding, some cases of baldness are simply about the hair follicles not getting a sufficient amount of blood... so increasing the blood flow to the hair follicles is what's needed in those situations (which is why some people have good results with simply using minoxidil). However in most cases baldness is a DHT issue (or possibly a combination of both).

It could be that your situation is a little bit from column A and a little bit from column B. So while the finasteride is blocking the DHT, your follicles still might not be getting enough blood flow without help from the Minoxidil. So either way, increased blood flow to the hair follicles is always a good thing.

Indeed, you are right. It was a heart medication and the other was prostate medication.

Also I agree with your reasoning on baldness and hope I will profit from the combi. :)
 

Lance

New Member
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4
Glad I could help guys! :)





Indeed, you are right. It was a heart medication and the other was prostate medication.

The last time I went for my prostate exam my doctor actually commented as to how small my prostate was and that it was because of the Propecia (I apologize if that might be "T.M.I." for some of you, but I figure any information on this topic can be helpful)
 

Armando Jose

Senior Member
My Regimen
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1,016
Minoxidil and Proscar/Finasteride work in two completely separate ways. Minoxidil doesn't block DHT, it simply increases the blood flow to your hair follicles (I believe it was originally used as a type of heart medication when it was discovered that it could also help in growing back/keeping hair). Where as Proscar/Finasteride, which was originally used as prostate medication, actually blocks DHT.

From my understanding, some cases of baldness are simply about the hair follicles not getting a sufficient amount of blood... so increasing the blood flow to the hair follicles is what's needed in those situations (which is why some people have good results with simply using minoxidil). However in most cases baldness is a DHT issue (or possibly a combination of both).

It could be that your situation is a little bit from column A and a little bit from column B. So while the finasteride is blocking the DHT, your follicles still might not be getting enough blood flow without help from the Minoxidil. So either way, increased blood flow to the hair follicles is always a good thing.

Hi Lance, common hairloss is a very special issue, thousand of people had a possitive results with ....
Bilateral ligature of the superficial temporal arteries and of the posterior auricular arteries is proposed as a treatment for seborrheic alopecia. The arterial circulatory dynamics are, thus, replaced by capillary circulatory dynamics. Hypoxia is produced which inhibits enzymatic systems and lessens nocuous action of androgen and lipid factors on the pilosebaceous effectors. The histologic study shows that the production of sebum is greatly reduced and the condition of the hair follicle is strikingly improved.

[h=1]New Treatment for Seborrheic Alopecia: The Ligature of the Arteries of the Scalp[/h]
 

WarLord

Established Member
Reaction score
13
It makes no sense at all.

If minoxidil basically prevents DHT attacked hairs from dying, then why after the culprit (DHT) is removed by finasteride, and minoxidil is dropped, they die anyway?

The explanations are inaccurate. Minoxidil simply keeps hair in the growth phase by some unknown mechanism. But it doesn't prevent DHT from attacking the hair follicle. Hairs treated with minoxidil are thus technically dead "zombie" hairs. Once you stop using minoxidil and the fragile balance is interrupted, the attacked hairs quickly fall out.

In contrast, 5-AR blockers solve hairloss at its root, by eliminating DHT. Therefore, if you add a 5-AR blocker to minoxidil, you must reckon with that it won't help you to keep the minoxidil-dependent hair, because these hairs are already damaged by DHT. 5-AR blockers can only save hairs that haven't been damaged by DHT yet.
 
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