Why do treatments work on 9/10 guys?

barryegan

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I know Propecia and Rogaine work more often than not, and Propecia actually works on 9 out of 10 guys, but does anyone have any idea what would cause the medicine to not work on 10% of the men?

I just started treatment 2 months ago, and like most others, I sometimes worry "What if I'm that 1/10 who it doesn't work for"
 

hair today gone tomorrow

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barryegan said:
I know Propecia and Rogaine work more often than not, and Propecia actually works on 9 out of 10 guys, but does anyone have any idea what would cause the medicine to not work on 10% of the men?

I just started treatment 2 months ago, and like most others, I sometimes worry "What if I'm that 1/10 who it doesn't work for"

Some guys hair loss is just too aggressive.
 

Johnny24601

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Some guys hair loss is just too aggressive.

I totally agree. Many men who are not on finasteride lose their hair very very quickly and in a year's time they can make a great leap on the Norwood scale. Add to that the fact that finasteride really takes a year to give results.....means the medication just can't keep up. Remember not all the androgens are blocked (which is a good thing IMO).
 

bababa

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Could it be that 1/10 person is someone older, or in later stages of male pattern baldness. When they give those figures, any stats infact, I always question it because you never get the full picture.

Peace...
 

pinkfloyd7

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so then shouldn't avodart be effective for almost all men ????? i mean it does block 98.5 percent of dht. that would eliminate any hair loss no matter how aggressive.
 

Sean68

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my understanding is that if your follicles are super sensitive then you can still be affected by the remaining 1.5%.
 

powersam

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also the mechanism for male pattern baldness is still not fully understood, so treatments might be missing something. plus not all hair loss is androgenic alopecia, the 10% may be affected by another condition.
 

kalbo

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I could be wrong, but that study also doesn't take into account whether or not it slowed down the hair loss. The study took note of what percentage maintained their hair after 5 years and found that 90% at least maintained. The rest could have been losing hair but at a slower rate than before. Doesn't mean that it didn't work at all.
 

Nick4441

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Hasn't worked for me at 6 months..lost 50% of my hair since taking Propecia...its made it worse.

Some suffer from Reflex Hydroandrogenicity which I think I may be. In this instance libido is increased and remains like it on the drug as well as other sides like oily skin and acne.

I think the ones who do not get sides or minimal sides that fade shortly away are those that benefit, the others with bad sides or long term sides its not beneficial...its just a theory of mine which I woudl hope with all the people on this board we could get nearer to answers to help us all.
 

Johnny24601

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re:

The exact function of DHT after development is not known so I am somewhat comforted by the fact that not all DHT is blocked by finasteride.
As has been repeated so many times on this site, results with finasteride take time.....usually a year to see results and sometimes longer. Apparently the follicles take time to adjust to life without (or perhaps less) DHT. I took a step back before taking a step forward.
Now if one had very aggressive male pattern baldness then the year adjustment time may just be too long and by the time their follicles are ready to turn the corner, it is just too late because of the agressive nature of their hairloss. Not to mention the fact that everything related to male pattern baldness is not known and though DHT is clearly a major contributor, there could be other factors that are more of a "control" to other men.
Also, maintaining what one has is considered a success. Therefore, some men who may have lost some density after using finasteride may have actually slowed down their hairloss considerably but because their male pattern baldness is so aggressive, they still lose hair counts so they go into the "failure" category. In reality finasteride could have actually been successful in slowing down their hairloss (which I consider a success) but we will never know for sure. I hope I explained my point of view on this subject matter.
 

antonio666

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depends on what you mean by work,if maintaining is your goal i would say you have about 30% chance of doing so,if regrowth is required 10%
chance,i hear a lot of guys come on here and say i have gone from norwood 2 to a 4 in 18 months but i am glad i got on treatment,otherwise i would be in a worse position,BULLSHIT a solid norwood 3 with no trace of thinning is not bad ,anything with diffuse thinning beyond a norwood 2 ,you may as well be a norwood 7 ,no diffrence at all
 

Johnny24601

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re:

depends on what you mean by work,if maintaining is your goal i would say you have about 30% chance of doing so,if regrowth is required 10%
chance,i hear a lot of guys come on here and say i have gone from norwood 2 to a 4 in 18 months but i am glad i got on treatment,otherwise i would be in a worse position,BULLSHIT a solid norwood 3 with no trace of thinning is not bad ,anything with diffuse thinning beyond a norwood 2 ,you may as well be a norwood 7 ,no diffrence at all

According to Merck, finasteride grows or maintains in 9 out of 10 men. Could they be over exaggerating their results? Sure but not by over 60%!!
Seriously pal your negative, bias, useless and uninformed comments are not helpful to anyone. Just because you are not happy with your hair does not mean you have the right to be so ignorant. I guess misery really does love company......
 
G

Guest

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I also think that finasteride works for EVERYONE. But working in this context means that the guys have more hair with finasteride than without. It works at least in slowing down the hairloss. I am one of those guys for which finasteride didn´t stop it but only slowed it down.
 

punkyqb

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finasteride is the #1 treatment for hairloss. finasteride rox. Just my personal opinion.
 
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