Why Aren’t We All On Seti? Seems Better Than finasteride

[Marco445]

After the Brotzu dissaster, I‘m strongly considering to start seti. According to what I’m reading on this forum, it’s basically maintainance but without sexual sides.

Unless you’re a nw6/7 or have bad donor area, that would in my opinion be a cure with a good hair transplant.

So why aren’t more people using seti? Too expensive? It seems too good to be true though, so perhaps I missed something during my brief research?

 

[d3nt3dsh0v3l]

Cost, experimental drug, shady source, verdict not officially out on efficacy... I mean there are a lot of reasons, lad.

And how about long term safety? Shockingly, some may not want to drug themselves indefinitely, especially considering the above factors.

But I mean who knows? To each his own, etc.

I am of the unpopular opinion that it seems easier to shave it off and invest time in making that work - finding friends who don't give a sh*t about hair, tricking a girl or two into falling in love with you (like many bald men have evidently done), having a fulfilling career, maintaining health so you have that peace of mind and quality of life, and being an intellectual, open person - rather than fight with my body, f*** around with unknown substances, have a high likelihood of my hair going to sh*t anyway, and basically riding this hairloss rollercoaster for the next decade. That sounds like a fuckton more work than shaving it off, taking a year or so to just get over my appearance and redoing my wardrobe and maybe finding some other sh*t to spend my life on...

The caveat to that is that if you subscribe to hlc2020's line of thought, the cure should be "right around the corner" and so presumably the maintainence drugs would simply tide you over till then. Who knows?

For me, it is Replicel/Follica/KY Choi/Tsuji or bust. In approximately that order. I don't really want to deal with systemic drug use. I'll just take the hit to attractiveness I'm getting older every day... my health will only tend to decline. Down the line, my body will tire and I'll care more about cancer and heart disease. I'd rather avoid systemic drug use given those concerns.

 

[itsjustsimon]

Trials are at 2g seti/day and the best price you can get on market right now is $6/g. Do your math.

And the other thing is we actually don’t know if it works and how well it works and second, you’re putting questionable compounds from China orally into your body. If you’re taking 60g of this sh*t a month and the purity is about 98% at best, you’re getting 1.2g of unknown compounds into your body so all sorts of fucked up sh*t can happen.

 

[BlueHorseshoe]

Also note the official trial results will be out in a few months so we'll have an official confirmation that it works or not.

The study done by Allergan seems to be far more sophisticated than Fidia’s Brotzu trial. Curious to know what your expectations are for Allergan trial and also if you know the process of going from a 2A trial to being available by prescription?

 

[itsjustsimon]

The study done by Allergan seems to be far more sophisticated than Fidia’s Brotzu trial. Curious to know what your expectations are for Allergan trial and also if you know the process of going from a 2A trial to being available by prescription?

Fidia did a trial? You mean interviews? That’s because it’s a f*****g joke

 

[Marco445]

Also note the official trial results will be out in a few months so we'll have an official confirmation that it works or not.

https://clinicaltrials.gov/ct2/show/NCT02781311

This is the study? Says it was finished march 13, so hopefully it's actually just a few months like you said.

 

[Marco445]

Is there anyway to test for purity?

 

[BlueHorseshoe]

I'm optimistic about the results. I think it will be good for maintenance but not for regrowth, similar to fina. And seti if good results will take a long time for commercialisation but that doesn't matter. The superior version, fevipiprant is coming out in 2020, hopefully since they changed the date from 2019 to 2020.

Yup

Why would it take a long time for commercilization? Isn’t Setipiprant already trialed for safety?

 

[itsjustsimon]

The trial that's finishing now is only the second one, a third one needs to be done too which will take a couple of years also. (if I'm correct)

Fevipiprant is already in the third trial.

But fevi is not for Androgenetic Alopecia or is it? I mean studies..

 

[westonci]

https://i.imgur.com/m8otWQI.png

Keep in mind that everything on this chart is for maintenance/prevention including seti.

@alebaba If you want regrowth you need to add microneedling + a growth agent ( i.e minoxidil, PGE1, PGE2, Bimatoprost, Latanoprost etc.) on top of seti.

 

[Marco445]

@westonci Is it better to take seti orally than topical? If it really maintains, the price is no problem, but I don't like the idea of taking this orally.
Currently only using min and keto shampoo as my regimen. I see you suggest PGE2, but is there anything else I should add?

 

[westonci]

@westonci Is it better to take seti orally than topical? If it really maintains, the price is no problem, but I don't like the idea of taking this orally.
Currently only using min and keto shampoo as my regimen. I see you suggest PGE2, but is there anything else I should add?

I would personally say oral at 2g/day is better than topical. But if you are able to apply seti topically twice a day i dont see why it wouldnt be the same. Its very hard to do if you have an active social life.

Also do whatever growth promoting agents you can afford or have access to. The more the better.

• minoxidil
• PGE1
• PGE2
• Bimatoprost
• Latanoprost

And always add a microneedling regimen with these

 

[ZenHead]

Just a suggestion, I began taking my setipiprant in enteric capsules - these capsules are designed to be acid resistant. They prevent drugs from being partially destroyed by stomach acid, as they break down in the intestines. This type of capsules break down and deliver the medicine about an hour after you swallow them. I’m sure stomach acid destroys some of the seti when regular capsules are used, so this might be helpful in letting the body absorb the entire dose and not just a portion of it.

 

[allthegains]

Just a suggestion, I began taking my setipiprant in enteric capsules - these capsules are designed to be acid resistant. They prevent drugs from being partially destroyed by stomach acid, as they break down in the intestines. This type of capsules break down and deliver the medicine about an hour after you swallow them. I’m sure stomach acid destroys some of the seti when regular capsules are used, so this might be helpful in letting the body absorb the entire dose and not just a portion of it.

How do you respond to the fact that the suppliers only guarantee 98% purity, and as someone above said, you are ingesting 1.2g of unknown substances every month?

 

[INT]

What will an average dosis of oral seti cost me approximately per month? Apologies if thas has been discussed here before.

 

[Ollie]

What will an average dosis of oral seti cost me approximately per month? Apologies if thas has been discussed here before.

About $380 a month if you're going by 2g a day at $6 / g... which is quite a lot when you look at it like that. As a student myself i'll have to wait until full time employment before that.

 

[INT]

About $380 a month if you're going by 2g a day at $6 /

You are kidding right?

 

[Ollie]

You are kidding right?

`Wish i was dude. Perhaps if you're buying in sizeable (annual) bulk you could get it down to 3000 a year. Having said that im sure there will be a time seti price drops.

 

[IdealForehead]

Also note the official trial results will be out in a few months so we'll have an official confirmation that it works or not.

This. I'm not spending $400 per month on a completely unproven treatment with no long term safety data. Keep in mind this is a brand new class of medication. Maybe it will be fine. Maybe it won't.

How many times have you seen in the news some lawsuit over a drug because after 2-5 years they find out it has some unforeseen side effect?

No one has ever used a PGD2 inhibitor before. For all anyone knows these could cause dementia or anything else really in the long run. They're completely unknown both for effectiveness and safety.

 

[washed_up]

If the seti male pattern baldness trials show efficacy, you can rest assured that many people will suddenly become asthmatic to get their hands on the even more powerful fevi that is looking pretty likely to come out in the next couple of years.