When Your Dad Throws Out Almost 20g Of Ru...

Georgie

Senior Member
My Regimen
Reaction score
2,721
this is actually just a gripe post because I’m in physical pain over this. I’m moving house today and my dad, bless his soul, said he’d come over to help me pack. He has keys to my place and thought he’d be helpful by coming over early to clear some things out. So he went through the fridge and started throwing things out that looked old or mostly used. My RU was kept into 2 sealed zip lock bags in my freezer, labeled “RU”. He thought it was some old food leftovers and threw it. Close to 20g of RU. I came home and saw the fridge was empty. He’d already thrown all the stuff down the apartment block rubbish shoot.

I

Cannot breathe

Dear god
 

IdealForehead

Senior Member
My Regimen
Reaction score
3,026
That's when you tell him he owes you $500 for it and use that go buy your daro. :) He can afford it.

RU is weak as sh*t anyway. It's just moving you to a final treatment resolution faster in the end. Long term you didn't lose out on much. I have 40 or 50 grams of RU sitting in my living room I'll never use. I have absolutely no use for it in general anymore.
 
Last edited:

Georgie

Senior Member
My Regimen
Reaction score
2,721
That's when you tell him he owes you $500 for it and use that go buy your daro. :) He can afford it.

RU is weak as sh*t anyway. It's just moving you to a final treatment resolution faster in the end. Long term you didn't lose out on much. I have 40 or 50 grams of RU sitting in my living room I'll never use. I have absolutely no use for it in general anymore.
I told him he doesn’t have to pay me back. I hate being a money grubber like that :/ Although it is incredibly inconvenient, and I don’t know how long I shall have to wait for daro. I’m hoping there’s no fallout from this. Been using RU a month now.
 

IdealForehead

Senior Member
My Regimen
Reaction score
3,026
im very upset about this

i need some more pics of you georgie to make myself feel better again

Hahahaha

Also georgie i don't know what your hangup is with money and taking help with it when it's available. He offered. You should take it and put it to your expenses. Unless there's some strings attached to taking help you've not mentioned. Your dad wouldn't mind I'm sure. He DID throw it out without asking. And he offered so you're not "grubbing".

As for fallout and daro, I doubt you'll notice anything. First of all, I got my daro within less than one week of ordering both times. I know it's hard in the moment (I used to freak out if I went anywhere and forgot my RU) but try to think long term. A week won't make a difference either way in the scheme of things and the other big changes you're making. If you want you could take spironolactone again just for the week to compensate.
 
Last edited:

sunchyme1

Senior Member
My Regimen
Reaction score
6,988
Hahahaha

Also georgie i don't know what your hangup is with money and taking help with it when it's available. He offered. You should take it and put it to your expenses. Unless there's some strings attached to taking help you've not mentioned. Your dad wouldn't mind I'm sure. He DID throw it out without asking. And he offered so you're not "grubbing".

As for fallout and daro, I doubt you'll notice anything. First of all, I got my daro within less than one week of ordering both times. I know it's hard in the moment (I used to freak out if I went anywhere and forgot my RU) but try to think long term. A week won't make a difference either way in the scheme of things and the other big changes you're making. If you want you could take spironolactone again just for the week to compensate.

yeah i agree

just chill for a week

take more photos of yourself and upload them to hairlosstalk.com

win win for everyone
 

Georgie

Senior Member
My Regimen
Reaction score
2,721
Hahahaha

Also georgie i don't know what your hangup is with money and taking help with it when it's available. He offered. You should take it and put it to your expenses. Unless there's some strings attached to taking help you've not mentioned. Your dad wouldn't mind I'm sure. He DID throw it out without asking. And he offered so you're not "grubbing".

As for fallout and daro, I doubt you'll notice anything. First of all, I got my daro within less than one week of ordering both times. I know it's hard in the moment (I used to freak out if I went anywhere and forgot my RU) but try to think long term. A week won't make a difference either way in the scheme of things and the other big changes you're making. If you want you could take spironolactone again just for the week to compensate.
I’ve just always felt weird accepting gifts or money from anyone. I know it was an accident so I’d also feel like a dick for taking money over something he didn’t mean to do.

I’m gonna wire the money through today, I’m I’m hoping by at least next week I will have my daro.
 
Last edited:

SteveTabernack

Banned
My Regimen
Reaction score
1,126
Yeah thats brutal.

Reminds me of the days I used RU. I was still living at home and this white powder was just sitting in our smallish freezer. For sure my mom must have come across it multiple times. Yet she didn't even ask once what this mysterious white powder was haha. Always perplexed me (but very fortunate).
 

Saulus

Banned
My Regimen
Reaction score
643
That's when you tell him he owes you $500 for it and use that go buy your daro. :) He can afford it.

RU is weak as sh*t anyway. It's just moving you to a final treatment resolution faster in the end. Long term you didn't lose out on much. I have 40 or 50 grams of RU sitting in my living room I'll never use. I have absolutely no use for it in general anymore.


What?

Werent you always a big fan of ru?

Whats your current regimen?
 

IdealForehead

Senior Member
My Regimen
Reaction score
3,026
What?

Werent you always a big fan of ru?

Whats your current regimen?

lol. Where have you been?

https://www.hairlosstalk.com/intera...01-a-better-topical-than-enzalutamide.105402/

Currently:

Daro 0.25%
minoxidil 5%
Niacinamide 5%
Panthenol 2.5%

I've been playing with desloratadine 1% and caffeine 0.5% but I have just cut them both out in case they are having anti-minoxidil effects by working as broad action anti-inflammatories.

Stopped RU about a month after I got on daro.

If you haven't read about daro, I posted a strength comparison with RU here:
https://www.hairlosstalk.com/intera...conversion-of-ru58841-to-darolutamide.109065/
 

davesmith420

Senior Member
My Regimen
Reaction score
1,703
Not to cause a war, but does RU even really work? I know in theory it should, but all of the forum posts I have seen on it have been very half and half; the people that did have success were usually on other things as well (e.g., finasteride, minoxidil, etc.).
 

IdealForehead

Senior Member
My Regimen
Reaction score
3,026
Not to cause a war, but does RU even really work? I know in theory it should, but all of the forum posts I have seen on it have been very half and half; the people that did have success were usually on other things as well (e.g., finasteride, minoxidil, etc.).

I discussed the problems with RU in the darolutamide thread, and in the link above to the strength comparison with daro, but in short the primary problem with RU is likely its short half life.

It has an antiandrogenic strength roughly equivalent to flutamide (which is a reasonably strong antiandrogen, used commonly in prostate cancer and other conditions, though nowhere near as strong as daro). However, RU has a serum half life of only 1 hour, and this likely corresponds to a scalp half life of around 3-5 hours.

Therefore it really needs to be applied twice a day to be effective. It also would need to be applied in HIGH doses (5-10%) on each application, to make up for the fact that 3-5 hours later, only half the RU you applied might still be there.

When you start doing that, the systemic absorption actually becomes considerable and it's not so clean a drug. I maintained for one year on 5% RU and 5% minoxidil twice daily but when I cut the dose of RU and dropped the minoxidil I lost hair. I went up to 7.5% RU until I got on daro, and once I stopped the RU, I definitely felt better overall, so there were some side effects creeping in at that high of a dose.

At 2 mL twice daily of RU 7.5%, you're getting a daily exposure of 300 mg RU, which is actually a very high dose when it absorbs systemically. And it costs a fortune. And the levels are bouncing up and down like a yoyo all day.

Overall not an ideal treatment. If you want to talk about theoretical "not for human use" unlicensed Chinese factory topical hair loss compounds, darolutamide is superior to RU in almost every way.
 

Georgie

Senior Member
My Regimen
Reaction score
2,721
I discussed the problems with RU in the darolutamide thread, and in the link above to the strength comparison with daro, but in short the primary problem with RU is likely its short half life.

It has an antiandrogenic strength roughly equivalent to flutamide (which is a reasonably strong antiandrogen, used commonly in prostate cancer and other conditions, though nowhere near as strong as daro). However, RU has a serum half life of only 1 hour, and this likely corresponds to a scalp half life of around 3-5 hours.

Therefore it really needs to be applied twice a day to be effective. It also would need to be applied in HIGH doses (5-10%) on each application, to make up for the fact that 3-5 hours later, only half the RU you applied might still be there.

When you start doing that, the systemic absorption actually becomes considerable and it's not so clean a drug. I maintained for one year on 5% RU and 5% minoxidil twice daily but when I cut the dose of RU and dropped the minoxidil I lost hair. I went up to 7.5% RU until I got on daro, and once I stopped the RU, I definitely felt better overall, so there were some side effects creeping in at that high of a dose.

At 2 mL twice daily of RU 7.5%, you're getting a daily exposure of 300 mg RU, which is actually a very high dose when it absorbs systemically. And it costs a fortune. And the levels are bouncing up and down like a yoyo all day.

Overall not an ideal treatment. If you want to talk about theoretical "not for human use" unlicensed Chinese factory topical hair loss compounds, darolutamide is superior to RU in almost every way.
I mean, it is generally still always a case of horses for courses. Everyone will react to things diffeeently. There are some people who grow all their damn hair back and get 0 side effects, but the majority of us are not so lucky. So for the 5% where RU is a virtual magical potion to say “this is the best treatment” would be like the minority percentage of people who survive advanced cancer treatment saying “chemo/radiotherapy is a sure cure”. Reality is, the majority will fight the battle and lose, a the while experiencing the side effects.
 

davesmith420

Senior Member
My Regimen
Reaction score
1,703
I discussed the problems with RU in the darolutamide thread, and in the link above to the strength comparison with daro, but in short the primary problem with RU is likely its short half life.

It has an antiandrogenic strength roughly equivalent to flutamide (which is a reasonably strong antiandrogen, used commonly in prostate cancer and other conditions, though nowhere near as strong as daro). However, RU has a serum half life of only 1 hour, and this likely corresponds to a scalp half life of around 3-5 hours.

Therefore it really needs to be applied twice a day to be effective. It also would need to be applied in HIGH doses (5-10%) on each application, to make up for the fact that 3-5 hours later, only half the RU you applied might still be there.

When you start doing that, the systemic absorption actually becomes considerable and it's not so clean a drug. I maintained for one year on 5% RU and 5% minoxidil twice daily but when I cut the dose of RU and dropped the minoxidil I lost hair. I went up to 7.5% RU until I got on daro, and once I stopped the RU, I definitely felt better overall, so there were some side effects creeping in at that high of a dose.

At 2 mL twice daily of RU 7.5%, you're getting a daily exposure of 300 mg RU, which is actually a very high dose when it absorbs systemically. And it costs a fortune. And the levels are bouncing up and down like a yoyo all day.

Overall not an ideal treatment. If you want to talk about theoretical "not for human use" unlicensed Chinese factory topical hair loss compounds, darolutamide is superior to RU in almost every way.

Thank you for the good post (as always). At times I was considering adding in RU for extra protection, however I think if I ever do go that route I would just add in dutasteride a couple times a week.

Also, it seems there has been a trend of PUA type cucks promoting RU on Youtube. Paid by Anagenic?

 

Georgie

Senior Member
My Regimen
Reaction score
2,721
Thank you for the good post (as always). At times I was considering adding in RU for extra protection, however I think if I ever do go that route I would just add in dutasteride a couple times a week.

Also, it seems there has been a trend of PUA type cucks promoting RU on Youtube. Paid by Anagenic?

LOL looks like he never had hairloss. NW3 pics or it didn’t happen.
 
Top