Nah I think all of it the severity, and aggressiveness of male pattern baldness are just entirely sensitivity to androgens which is probably genetic too. Very little you can really do directly to change male pattern baldness with anything but the 2 crappy things we have right now. Unlike many other conditions I dont think environment plays much if any role.
What Really Causes Hair loss - Best Kept Secret by Pharma Companies? or not?
- Thread starter james555
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It's still a garbage treatment in the grand scheme of things. Barely regrows, is known to be d*ck poison (can cause permanent erectile dysfunction), can cause gynecomastia and reduces libido. Requires frequent oral intake and theres no guarantee that it will work to any degree.
I'd much rather go for a Histogen treatment once a year for maintenance. No side effects (known, at least), one time treatment and performs better than Finasteride.
The thing is, in human physiology nothing is ever simple. Everything the body goes through is never down to one hormone or one pathway, there's always cross-communications and other factors both upstream and downstream. There's always more than one factor.
Quite often blocking one pathway should be enough, if it is a necessary step however. I do believe androgens play an important role in male pattern baldness but as other factors have been found such as wnt, pgd2, igf and dkk-1, there maybe others who won't see as much success by just blocking dht as these factors may also be playing a role. These factors are also part of the 'male pattern baldness gene'.
Instead of inhibiting dht ,however, more work should be done to block the androgen receptors in the scalp, dht is useless if there is nothing for it to bind to and I hope that's where CB will come in.
Though lets just hope blocking dht is enough for us.
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If you think about it, finasteride is the only treatment which has been shown to actually try and tackle the underlying process to male pattern baldness. You may call it garbage but it's the only treatment which has been tried and tested. Also, what people tend to forget is that when it came out there were no other hairloss treatments it could be compared to, it really was in a league of it's own.
I know that there are other treatments in development like pgd2 inhibitors, CB, histogen and replicel but these are being developed nearly two decades after finasteride was released. There have been many failures along the way and the sad thing is histogen and replicel may become failures themselves especially with the results of their trials. Though i hope that if they fail they just become stepping stones to even better treatments.
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Too right. The vast amounts of misinformation about hairloss is the biggest issue today. So many men today are not just armed with with no information, but armed with incorrect information...
If you know nothing about it, you may find the answers, but if you believe this ****e and think you're doing the right thing, then that's even worse!
If you know nothing about it, you may find the answers, but if you believe this ****e and think you're doing the right thing, then that's even worse!
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I wouldnt say Histogen may fail. We know it works. We know it continues to work even 6-12 months after the initial injection. I'd much rather have that than friggin finasteride and the poison that comes along with it. Next two things to look forward to, IMO, are Follica and Pilofocus+Acell.
But what is correct and what isn't? We know DHT is a prime suspect of male pattern baldness but what else should we be looking at?
There isn't as much research into the development of male pattern baldness as other problems as it is cosmetic so there is no pressure pushing scientists into understanding the process so we might never see the full picture as it is not necessary.
finasteride is a barbaric way of "trying" to halt hair loss. DHT is not the problem since people get sides when finasteride is used, it is the SENSITIVITY of the follicles to DHT. This is why finasteride is so barbaric and a very poignant way of dealing with male pattern baldness. What needs to be done is make those hairs resistant to DHT NOT TO BLOCK DHT which is needed by the body. I am hopeful that histogen can pave the way.