what causes body hair? dht or testosterone

whitemogs

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so yea i was wondering is body hair any indicator of whats effecting ur scalp? if you have alot of body hair like on ur arms and legs etc is that high levels of dht? or high levels of testosterone? thanks for the responses!
 

michael barry

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both......................


primarily DHT of course, but body hairs have androgen receptors which can uptake other male hormones like testosterone, andro, DHEA, etc. DHT, made in the outer root sheath of hair follicles from testosterone, has about five times the affinity for the androgen receptor though (like a magnet and steel if you will), therefore when its made, it often binds. When DHT binds, it seems to bind pretty solidly and the DNA within the follicle reads it and follows preprogrammed instructions. In body hair this instruction is apparantly "grow hair" and the dermal papilla releases growth factors to the other parts of the follicle like the keratinocytes, root sheath, epilitihial cells, etc.

In head hair over time, the opposite begins to occur.



Docj077 has pointed out that alot of men with male pattern baldness have certain variants of the androgen receptor making it more active or in greater prevalence in their hairs. This might account for the many "hairy men" who also have alot of body hair. However, some smooth men also have baldness, so its more complicated than just that as Doctor will tell you.


Overall, being a really hairy dude isnt a good sign for your head hair's future, but it doesn't mean baldness is absolutely going to happen because there are plenty of hairy men who dont bald, but more often than not,,,,,,,,,,,,,,,,,they seem to.
 

IBM

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so the androgens is like a fuel. Barry once defined male caracteristhics (for example a 30's men) what happen if there's lack or low androgens in our body?
 

whitemogs

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nice response michael barry makes alot of sense in that way. dht is worse but testosterone has a lower level of damage as well. so blocking some testosterone could as well be benificial for your scalp hair i would assume, and high levels of T would have a negative effect on your scalp. another thing im pretty hairy legs and arms, i take finasteride and minoxidil do you think this is the best choice? all i have is a receded hairline going into nw3 if it doesnt get better
 

michael barry

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so blocking some testosterone could as well be benificial for your scalp hair i would assume, and high levels of T would have a negative effect on your scalp. another thing im pretty hairy legs and arms, i take finasteride and minoxidil do you think this is the best choice? all i have is a receded hairline going into nw3 if it doesnt get better


Youre on the two most researched treatments that there are. If you add nizoral and use it twice a week, you will be on the "big three". That should be fine. If youre still losing hair using all three...........................you really might have aggressive Androgenetic Alopecia to be honest.


As far as blocking T. Blocking all the DHT possible is the most accepted way to inhibit further baldness first, then perhaps block T with a receptor blocker on top of it (like spironolactone, fluridil). Nizoral should block some receptor sites, but we dont know exactly how much the ketoconazole in nizoral blocks them. We know it lessens the activity of the sebaceous glands and shrinks them by about 19 percent. So at least at the level of the sebaceous glands, nizoral is a pretty good anti-androgen.


You might add spironolactone cream up front around the temple area, but admittedly spironolactone creams are a hassle. They are best used twice a day, about 12 hours apart along with the minoxidil. They are androgen-receptor blockers. These are the "accepted" things, not the experimental things.



Dutasteride blocks so much DHT it might be able to halt hairloss all in itself in many. Unfortunately it also blocks the type one alpha five reductase enzyme which is in the bodies deeper tissues and in the brain. So we dont know long term just how safe it is to be on that for decades at a time. It would be great if we could find a finasteride that was capable of blocking type two created DHT as effectively as dutasteride, but didnt inhibit type one....................................



IF you want to stop your hairloss in its tracks, use finas and topical spironolactone cream............................that should stop it. If it doesn't, you probably just have very aggressive/severe male pattern baldness.
 

Nathaniel

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Thats exactly the reason why I don't jump to dutasteride, I really want to because that 98% block of type 2 is so attractive, but then putting up with 50% of type 1 blockage just bugs me out.
 

whitemogs

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Yea I'm going to have to add nizoral and spironolactone cream. It does seem to be stable only that my current hair has thinned from minoxidil foam so if all goes well it should thicken up in a few months. And yes dutasteride is effective but some people report losing all frontal hair from the higher increases in testosterone... so its a tough choice. Michael barry what's your opinion on oral spironolactone? 50 mg doses? Mainly is a shed going to arise from the oral spironolactone? thanks for the responses and michael barry too.
 

michael barry

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my opinion is to use topical spironolactone twice a day, about twelve hours apart.


not internal. you'd be blocking the androgen receptors all over your body, plus spironolactone is a potassium sparing diuretic. There are alot of consequences possibly long term from this.



Sometimes I feel like screaming out. Finas, topical spironolactone twice a day, nizoral

If you are just starting to lose your hair, that above should keep it. If you add minoxidil, you might get some back. If you are a newbie, that a cheap effective regimine considering that you can make minoxidil and spironolactone yourself, get finas online.
 

flimflam

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michael

glad you're on these forums :)

I'm quite hesitant to get on dutasteride for the type-I reasons you mention - why isn't there a type-II only version of dutasteride? Is inhibiting type-I a "side-effect" of the way the drug works or was it designed that way?

I'd jump on dutasteride if it wasn't for that :/

cheers
 

RaginDemon

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michael barry said:
my opinion is to use topical spironolactone twice a day, about twelve hours apart.


not internal. you'd be blocking the androgen receptors all over your body, plus spironolactone is a potassium sparing diuretic. There are alot of consequences possibly long term from this.



Sometimes I feel like screaming out. Finas, topical spironolactone twice a day, nizoral

If you are just starting to lose your hair, that above should keep it. If you add minoxidil, you might get some back. If you are a newbie, that a cheap effective regimine considering that you can make minoxidil and spironolactone yourself, get finas online.

MB, thanks for the informaiton, much appreciated. I am going to give topical spironolactone a try.

Any idea where I can purchase it online?
 

michael barry

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minoxidil.com

genhair.com


make it yourself. crushed tablets in dermovan or cetaphil cream or oil of olay cream...........

Have to check, but I think its 16 tablets per 60ml. Ask Bryan or Old Baldy for the exact ratio. Wait about a day, and the powder is absorbed in the cream. Apply to the problem areas only. No need to do the whole head or in the wreath----finas and nizoral should take care of that.
 

couldntthinkofaname

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cortisol

one sign of cushing syndrome is increased body hair
 

Chromedome1990

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cortisol

one sign of cushing syndrome is increased body hair
Nicely done bumping a nearly 11 year old thread. I'm sure you'll get a response from one of these ancient posters, that is if they haven't already "moved on" (just shave it bro/hair transplant/suicide).
 
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