Risugo
Established Member
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Here is a extract from Dr. L. Pickart's skinbiology,
"With regards to hair growth. This is a list of compounds that act similar to GHK on human genes. Note that minoxidil is number 5 of over 1,300 compounds tested. The data is from Cmap at the Broad Institute in Boston.
We are slowing digging out the genetic data on GHK.
In Cmap, in order of similarity, GHK seems to have actions similar to:
1. STOCK1N-35874 - I don't know what this is.
2. 6-bromoindirubin-3'-oxime - keeps stem cells going - so does GHK
3.tiletamine - Tiletamine is a dissociative anesthetic and pharmacologically classified as an NMDA receptor antagonist. It is related chemically and pharmacologically to other anesthetics in this family such as ketamine and phencyclidine. Tiletamine hydrochloride exists as odourless white crystals. Sorenson found copper complexes reduce pain as much as morphine.
4. Cefalexin - GHK also inhibits infections -
Cefalexin is a first-generation cephalosporin antibiotic introduced in 1967 by Eli Lilly and Company. GHK-Cu has powerful anti-infection effects in mice. We found this at Procyte and a Greek Univ found the same in 1999.
5. minoxidil - we grow hair too
6. Prestwick-857 - a UK company - I don't know what this is.
7. Citiolone is a drug used in liver therapy. It is a derivative of the amino acid cysteine. GHK started by keeping liver cells alive.
8. Nystatin is a polyene antifungal drug to which many molds and yeast infections are sensitive, including Candida. As above, GHK-Cu has powerful anti-infection effects in mice. We found this at Procyte and a Greek Univ found the same in 1999.
9. Bambuterol (INN, marketed by AstraZeneca under the trade names Bambec and Oxeol) is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma. It is a prodrug of terbutaline.[1]
10. rilocaine - Prilocaine is a local anesthetic of the amino amide type. In its injectable form (trade name Citanest), it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia (IVRA). GHK-Cu has powerful anti-infection effects in mice. We found this at Procyte and a Greek Univ found the same in 1999.
11. Quipazine is a piperazine drug used in scientific research. It is a moderately selective serotonin receptor agonist, binding to a range of different serotonin receptors, but particularly to the 5-HT2A[1] and 5-HT3.[2]
12. Epirizole is a nonsteroidal anti-inflammatory drug. GHK has many anti-inflammatory actions.
.............
Also, Cmap led me to a big, big file from PNAS, GHK is a carbonic anhydrase inhibitor.
Along with pilocarine and (STOCK1N-35874 diclofenamide)
Carbonic anhydrase inhibitors are a class of pharmaceuticals that suppress the activity of carbonic anhydrase. Their clinical use has been established as antiglaucoma agents, diuretics, antiepileptics, in the management of mountain sickness, gastric and duodenal ulcers, neurological disorders, or osteoporosis. [1][2][3] GHK-Cu rebuild bones and has strong anti-stomach ulcer and anti-duodenal ulcer activities."
"With regards to hair growth. This is a list of compounds that act similar to GHK on human genes. Note that minoxidil is number 5 of over 1,300 compounds tested. The data is from Cmap at the Broad Institute in Boston.
We are slowing digging out the genetic data on GHK.
In Cmap, in order of similarity, GHK seems to have actions similar to:
1. STOCK1N-35874 - I don't know what this is.
2. 6-bromoindirubin-3'-oxime - keeps stem cells going - so does GHK
3.tiletamine - Tiletamine is a dissociative anesthetic and pharmacologically classified as an NMDA receptor antagonist. It is related chemically and pharmacologically to other anesthetics in this family such as ketamine and phencyclidine. Tiletamine hydrochloride exists as odourless white crystals. Sorenson found copper complexes reduce pain as much as morphine.
4. Cefalexin - GHK also inhibits infections -
Cefalexin is a first-generation cephalosporin antibiotic introduced in 1967 by Eli Lilly and Company. GHK-Cu has powerful anti-infection effects in mice. We found this at Procyte and a Greek Univ found the same in 1999.
5. minoxidil - we grow hair too
6. Prestwick-857 - a UK company - I don't know what this is.
7. Citiolone is a drug used in liver therapy. It is a derivative of the amino acid cysteine. GHK started by keeping liver cells alive.
8. Nystatin is a polyene antifungal drug to which many molds and yeast infections are sensitive, including Candida. As above, GHK-Cu has powerful anti-infection effects in mice. We found this at Procyte and a Greek Univ found the same in 1999.
9. Bambuterol (INN, marketed by AstraZeneca under the trade names Bambec and Oxeol) is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma. It is a prodrug of terbutaline.[1]
10. rilocaine - Prilocaine is a local anesthetic of the amino amide type. In its injectable form (trade name Citanest), it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia (IVRA). GHK-Cu has powerful anti-infection effects in mice. We found this at Procyte and a Greek Univ found the same in 1999.
11. Quipazine is a piperazine drug used in scientific research. It is a moderately selective serotonin receptor agonist, binding to a range of different serotonin receptors, but particularly to the 5-HT2A[1] and 5-HT3.[2]
12. Epirizole is a nonsteroidal anti-inflammatory drug. GHK has many anti-inflammatory actions.
.............
Also, Cmap led me to a big, big file from PNAS, GHK is a carbonic anhydrase inhibitor.
Along with pilocarine and (STOCK1N-35874 diclofenamide)
Carbonic anhydrase inhibitors are a class of pharmaceuticals that suppress the activity of carbonic anhydrase. Their clinical use has been established as antiglaucoma agents, diuretics, antiepileptics, in the management of mountain sickness, gastric and duodenal ulcers, neurological disorders, or osteoporosis. [1][2][3] GHK-Cu rebuild bones and has strong anti-stomach ulcer and anti-duodenal ulcer activities."