Update From The God Himself - Dr. Takashi Tsuji

BigOl'BaldingHead

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Shiseido or Follica should stop and vitalize the diffused hair. If Tsuji ain't affordable they should deliver within 5-10 years

Follica and Replicel will be out in less than 5 years. Follica is filling for FDA approval in 2020 and Replicel is almost done with their last trial before commercialisation in Japan. But I'd agree that this is the 'cure' for diffused thinners.
 

PlsTsuji

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Follica and Replicel will be out in less than 5 years. Follica is filling for FDA approval in 2020 and Replicel is almost done with their last trial before commercialisation in Japan. But I'd agree that this is the 'cure' for diffused thinners.
Isn't follica just dermarollimg and applying minoxidil?
 

MrV88

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Follica and Replicel will be out in less than 5 years. Follica is filling for FDA approval in 2020 and Replicel is almost done with their last trial before commercialisation in Japan. But I'd agree that this is the 'cure' for diffused thinners.
Yip, that was what I meant. Go for them, stabilize your hair and wait until it gets affordable... :)
 

itsjustsimon

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Follica and Replicel will be out in less than 5 years. Follica is filling for FDA approval in 2020 and Replicel is almost done with their last trial before commercialisation in Japan. But I'd agree that this is the 'cure' for diffused thinners.

RCH will never come out and Follica will be a little bit better than minoxidil and dermarolling. After 30 years, finasteride will still be the best treatment hahah
 

disfiguredyoungman

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This is utterly absurd and concrete proof they have nothing. If they actually developed a full-blown cure for hair loss, it would make absolutely no economic sense to release it at that price point; they would have so few customers that the margin would be deminimis. If you only have a few hundred takers, how much profit could you possibly realize? Let's say the net margin was 100% - a very high margin for a cosmetic procedure. At 100 takers, the gross would be a paltry $40m; biotechs don't get out of bed for less than 10x that number. IF they had the tech to cure hair loss and the bottle neck was the process, they would have investors lined up around the world begging to partner to fund the research and/or build out the capacity, yet they claim it will take TEN YEARS to reach affordable economies of scale? LOL! This is total bullshit.

You guys need to stop holding out Japan as some sort of paragon of biotechnology. Name a top-ten pharma that is Japanese; Japan's biotech industry is actually quite incipient, and the "cure" will not be coming from Japan. They are actually pretty backwards when it comes to medicine generally due to their national health system and its rationed-care model; they just don't have the capital for serious Pharma investment. I mean, up until recently, this was a country where it was common place for doctors to lie to patients about their prognosis - they'd often tell terminal patients that they were fine and had many years left, and only has it been in the last few years where this practice has come to a stop. It's a weird place, with lots of very weird customs that permeate every aspect of their culture; ever heard of their wide-spread "blood type theory?" Quakery is common place.

The next commercial, effective treatment will come from the West, and it almost certainly will be Follica. A decade from now, Follica will be growing multiple NWs while Tsuji is still babbling on about $400k cures.

Organ Technologies/ Riken is government funded they don't need to economize every step of their research, they need to offer results. And even disregarding that you make a lot of baseless assumptions. The hairloss industry is considered to be a unprofitable market, it may seem different to us because we are desperate but the profit from minoxidil and finasteride has been described as disappointing. Furthermore as a government funded institution they wouldn't want to outsource the project to investors 'all over the world'. The complexity of the procedure would make that a lengthy process as well. This isn't a mechanical intervention, I am sure you need extremely specialized equipment and people.

The rest of your post is just talk in layman's terms about a country that is heavily exotified by the West. Yeah, blood type theory is a bogus belief, that has absolutely NOTHING to do with Japanese medical research. It's pseudo-science popular in Japanese women's magazines,completely equivalent to Western horoscopes. You wouldn't denounce all of Western medicine based on the existance of horoscopes. Or even worse: Pseudoscience such as homeopathy which is state funded in many Western countries despite the absolute lack of empirical proof. I think the latter is a much greater affront against the scientific integrity of a culture. So if you discount Japanese medicidal research because of something fringe as blood type theory the same is true twice as much for Western medicine and homeopathy.
Last but not least, Japanese Biomedicine is already leading in a couple of niche fields such as the production of an artifical womb, thanks to their easier regulations.
https://www.tohoku.ac.jp/en/press/artificial_womb_raises_hope.html

I can see the same happening for hairloss.
 

HairSuit

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Organ Technologies/ Riken is government funded they don't need to economize every step of their research, they need to offer results. And even disregarding that you make a lot of baseless assumptions. The hairloss industry is considered to be a unprofitable market, it may seem different to us because we are desperate but the profit from minoxidil and finasteride has been described as disappointing. Furthermore as a government funded institution they wouldn't want to outsource the project to investors 'all over the world'. The complexity of the procedure would make that a lengthy process as well. This isn't a mechanical intervention, I am sure you need extremely specialized equipment and people.

The rest of your post is just talk in layman's terms about a country that is heavily exotified by the West. Yeah, blood type theory is a bogus belief, that has absolutely NOTHING to do with Japanese medical research. It's pseudo-science popular in Japanese women's magazines,completely equivalent to Western horoscopes. You wouldn't denounce all of Western medicine based on the existance of horoscopes. Or even worse: Pseudoscience such as homeopathy which is state funded in many Western countries despite the absolute lack of empirical proof. I think the latter is a much greater affront against the scientific integrity of a culture. So if you discount Japanese medicidal research because of something fringe as blood type theory the same is true twice as much for Western medicine and homeopathy.
Last but not least, Japanese Biomedicine is already leading in a couple of niche fields such as the production of an artifical womb, thanks to their easier regulations.
https://www.tohoku.ac.jp/en/press/artificial_womb_raises_hope.html

I can see the same happening for hairloss.
Sorry. Have to to take issue with your explanation of homeopathy. “Imitation is the best form of flattery”, as it’s said. A number of drugs that exist today are a chemically altered and derived duplicate of naturally occurring homeopathic remedies. Those remedies, being naturally occurring, cannot be patented and so the chemical derivative is found so that it can be.
 

disfiguredyoungman

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Sorry. Have to to take issue with your explanation of homeopathy. “Imitation is the best form of flattery”, as it’s said. A number of drugs that exist today are a chemically altered and derived duplicate of naturally occurring homeopathic remedies. Those remedies, being naturally occurring, cannot be patented and so the chemical derivative is found so that it can be.

Homeopathy is like jerking off into the ocean in hopes of making some b**ch pregnant.

It is by design not just a natural remedy but a dilution of the active agent until its impotent.
 
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HairSuit

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Homeopathy is like jerking off into the ocean in hopes of making some b**ch pregnant.

It is by design not just a natural remedy but a dilution of the active agent until its impotent.
Hahahaha. I understand your point and I’m not getting into this discussion here but , the same as some guys experience sides on finasteride here and others don’t, it has been the experience of many for centuries that it works, and others would say not. Those that don’t get sides would tell you that the sides are all in people’s heads. They are not. Same with this. In the right hands, it’s an effective tool. Back on topic.
 

MrV88

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You’re making one giant assumption that shiseido is actually going to do anything and be significantly better than the best responder (20% after 2 years) from the safety trial.
The whole forum is an assumption..

I'm not betting on new hair thanks to Shiseido, but maintaining or get thinning hair back to normal.
 

YanDjin

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This is utterly absurd and concrete proof they have nothing. If they actually developed a full-blown cure for hair loss, it would make absolutely no economic sense to release it at that price point; they would have so few customers that the margin would be deminimis. If you only have a few hundred takers, how much profit could you possibly realize? Let's say the net margin was 100% - a very high margin for a cosmetic procedure. At 100 takers, the gross would be a paltry $40m; biotechs don't get out of bed for less than 10x that number. IF they had the tech to cure hair loss and the bottle neck was the process, they would have investors lined up around the world begging to partner to fund the research and/or build out the capacity, yet they claim it will take TEN YEARS to reach affordable economies of scale? LOL! This is total bullshit.

You guys need to stop holding out Japan as some sort of paragon of biotechnology. Name a top-ten pharma that is Japanese; Japan's biotech industry is actually quite incipient, and the "cure" will not be coming from Japan. They are actually pretty backwards when it comes to medicine generally due to their national health system and its rationed-care model; they just don't have the capital for serious Pharma investment. I mean, up until recently, this was a country where it was common place for doctors to lie to patients about their prognosis - they'd often tell terminal patients that they were fine and had many years left, and only has it been in the last few years where this practice has come to a stop. It's a weird place, with lots of very weird customs that permeate every aspect of their culture; ever heard of their wide-spread "blood type theory?" Quakery is common place.

The next commercial, effective treatment will come from the West, and it almost certainly will be Follica. A decade from now, Follica will be growing multiple NWs while Tsuji is still babbling on about $400k cures.

Riken seems to have the cure. Their research center have very good track record and the science backing up theirs method seems solid.
How did you judge that it would not make sense at that price point? what you describe is really wrong! the factors that make the price of a product are :
- the R&D cost and the cost of production of the necessary equipment and employees.
- Offer and demand.
Given the fact that the demand is exceeding the offer by a really big deal, they are going to judge of the maximum price they can charge and still maximize their capacity of treatment. in other terms, if we can make the treatment for 40 000 people a year, what is the highest price we can charge and still have these 40 000 clients.
if we speculate on 40 000 clients a year and 200 000 dollars for the procedure. that's 8 billion dollars. not too bad.
 

Ollie

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RCH will never come out and Follica will be a little bit better than minoxidil and dermarolling. After 30 years, finasteride will still be the best treatment hahah

No i bet RCH will come out within the next 2 years. However ironically really good results will only come to those already on maintenance treatments (finasteride).
 

Rho Gain

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Organ Technologies/ Riken is government funded they don't need to economize every step of their research, they need to offer results. And even disregarding that you make a lot of baseless assumptions. The hairloss industry is considered to be a unprofitable market, it may seem different to us because we are desperate but the profit from minoxidil and finasteride has been described as disappointing. Furthermore as a government funded institution they wouldn't want to outsource the project to investors 'all over the world'. The complexity of the procedure would make that a lengthy process as well. This isn't a mechanical intervention, I am sure you need extremely specialized equipment and people.

Why would the government fund an expensive effort to address a non-terminal condition that won't turn a profit? That's the dumbest thing I've ever heard.

Japanese researcher: "Hey Hiro, I think I'm going to ask the government for a grant to study colon cancer. Horrible disease, kills so many, and an effective treatment would be really profitable."

Japanese researcher 2: "Daisuke, are you f*****g nuts? The government will never give you yen to study colon cancer. Tell them you want to cure hair loss. It only affects a percentage of men, it doesn't kill anybody, and it won't ever make any money. Oh yeah, if you actually manage to cure it, only the .1% will be able to afford the therapy. The bureaucrats will love it - gambatane!"

PS. Blood theory isn't just popular in women's magazines - it's so widely practiced that it is often included on job applications.
 
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ZP31

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Why would the government fund an expensive effort to address a non-terminal condition that won't turn a profit? That's the dumbest thing I've ever heard.

Japanese researcher: "Hey Hiro, I think I'm going to ask the government for a grant to study colon cancer. Horrible disease, kills so many, and an effective treatment would be really profitable."

Japanese researcher 2: "Daisuke, are you f*****g nuts? The government will never give you yen to study colon cancer. Tell them you want to cure hair loss. It only affects a percentage of men, it doesn't kill anybody, and it won't ever make any money. Oh yeah, if you actually manage to cure it, only the .1% will be able to afford the therapy. The bureaucrats will love it - gambatane!"

PS. Blood theory isn't just popular in women's magazines - it's so widely practiced that it is often included on job applications.

Because creating hair follicles from stem cells is the first step in being able to create larger organs.
 

Rho Gain

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Because creating hair follicles from stem cells is the first step in being able to create larger organs.

Then why even bother commercializing it? If the hair loss market is as anemic as everyone says (and it is), why add the extra burden of investing in the infrastructure to sell something that only a few hundred - at best - will ever pay for?

Again, if they actually figured out the tech, there would be any number of large pharmas that would want to partner, licensing the tech to sell around the world, leveraging economies of scale, not keeping it locked up in Japan at $400k a pop. It's just such absolute nonsense.
 

-Synergy-

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With the advancement of stem cell technology we are finally in position to cure hair loss.

Invest in stem cells now or maybe clean energy to have the money in 10 years for the transplant. If you invested 5k in apple 12 years ago you would easily have the money today. Lol it’s time to Elon musk this sh*t jk
 
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