Topical Estrogen in Men?

persistentone

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Has topical estrogen ever been studied for male pattern baldness? As I understood it this is avoided for fear of systemic absorption, but how effective is it?

I was studying Propecia's sexual side effects, and one interesting result of that research is that the testosterone production cycle in men normally does produce some estrogen as well. And that estrogen level corresponds in more or less linear fashion to sexual desire in men. When Propecia stops testosterone production it is also stopping estrogen. The study I was reading reported that as testosterone was lowered, sexual desire was lowered. Erectile function however was maintained until some threshold testosterone level was reached. Lower Estrogen also resulted in lower sexual desire in men.

So it does make you wonder if Propecia's negative sexual side effect in men might have causes in both a lower testosterone level and also a lower estrogen level. Testosterone cannot be easily replaced without fighting against Propecia and causing male pattern baldness. But it does make you wonder if some trivial amount of supplemental estrogen in men might be an appropriate therapy to fight the lower sexual desire as a result of Propecia's effects on lowering testosterone and estrogen.

And to the extent that topical estrogen on the scalp might also force some hair growth, you would think they could find a dose that would only cause a minimal systemic absorption and that systemic absorption might be desirable against fighting the effects of Propecia.
 

rwhairlosstalk

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Hum. Well let me know because short of putting sh-t on top of my head I'm willing to try almost anything.
 

psyhotria

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When Propecia stops testosterone production it is also stopping estrogen.
(1) "Propecia" is a brand name... (2) Finasteride does not stop the production of testosterone nor estrogen. (3) The effect of estrogen on human (also man) scalp hair has been studied indeed.
 

opti

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Finasterid does increase your Estrogen levels while it doesnt lower the T levels.

FInasterid blocks 5ar (which makes testosteron to dht) ,so more Testosteron is there for the Aromatase which converts testosteron into estradiol(estrogen)
 

persistentone

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(1) "Propecia" is a brand name... (2) Finasteride does not stop the production of testosterone nor estrogen. (3) The effect of estrogen on human (also man) scalp hair has been studied indeed.

What was the result of the research on topical estrogen in men?

- - - Updated - - -

Finasterid does increase your Estrogen levels while it doesnt lower the T levels.

FInasterid blocks 5ar (which makes testosteron to dht) ,so more Testosteron is there for the Aromatase which converts testosteron into estradiol(estrogen)

So it turns out that Finasteride *increases* rather than lowers estrogen, per this link:

http://www.propeciahelp.com/forum/viewtopic.php?t=7

Here is a summary of the interesting research I had originally encountered that showed lowered libido in aging males may be partly attributable to declining estrogen:

http://news.yahoo.com/low-estrogen-linked-flagging-sex-drive-men-study-212720770.html

So, as usual, the facts are highly non trivial. Not clear when/how to tinker with estrogen levels in males....
 

abcdefg

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Yeah even recent news articles show we have no idea whats really going on or why that happens. Doesnt make taking propecia sound very reassuring to me.
 

persistentone

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So here is what I found on a quick review for topical estrogen in men:

http://www.follacure.com/t/estrogenB

The executive summary is that topical estrogen can - in many cases - completely reverse hair loss in men. Unfortunately, the doses required to do this are extremely high and have high probability of feminizing the man. Low doses of topical estrogen - while avoiding the systemic effects - apparently don't have much effect on hair loss either.
 

opti

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i wouldnt recommend topical estrogen since of the side effects....

better try Progesteron,reduces DHT while antagonizes estrogenic effects
 

persistentone

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i wouldnt recommend topical estrogen since of the side effects....

better try Progesteron,reduces DHT while antagonizes estrogenic effects

Has this been studied topically in men and if yes where are the references?
 
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