Chromeo
Established Member
- Reaction score
- 71
Hahah, well, if you're right, that's even better.
Topical Cetrizine for Hair Loss instead of Finasteride (Propecia)
- Thread starter casperz
- Start date
-
- Tags
- cetirizine pgd2 blocker
Hahah, well, if you're right, that's even better.
knowingyou
Established Member
- Reaction score
- 2
JulioGP
Member
- Reaction score
- 6
Guys, unfortunately I bring bad news, at least for me.
I just talked to my doctor who specializes in Glaucoma. Unfortunately I can not longer use the CTZ, because who is prone to glaucoma (increased eye excavation) should stay away from antihistamines and in my case, especially for my type of work which does not want to go into details here.
Who has the propensity Glaucoma closed should keep away from antihistamines, because these substances can increase the excavation of the cornea, as well as steroids can cause the excavation, antihistamines can increase it if you are a candidate for this.
In this case, I'm not going to counteract this kind of information, because even though the risk is minimal can not run it due to my propensity to Glaucoma.
I am very sad at having to abandon the treatment because I was depositing MANY hopes the same. : (
Here is some information about it:
"The compounds as sedative antihistamines can cause headache, sedation, somnolence, decreased psychomotor activity and anti-muscarinic effects (urinary retention, dry mouth, blurred vision, narrow-angle glaucoma and pyloroduodenal obstruction)."
I come very important to warn them about it, because someone may be in a situation similar to mine, and I saw people worrying too much about it.
I just talked to my doctor who specializes in Glaucoma. Unfortunately I can not longer use the CTZ, because who is prone to glaucoma (increased eye excavation) should stay away from antihistamines and in my case, especially for my type of work which does not want to go into details here.
Who has the propensity Glaucoma closed should keep away from antihistamines, because these substances can increase the excavation of the cornea, as well as steroids can cause the excavation, antihistamines can increase it if you are a candidate for this.
In this case, I'm not going to counteract this kind of information, because even though the risk is minimal can not run it due to my propensity to Glaucoma.
I am very sad at having to abandon the treatment because I was depositing MANY hopes the same. : (
Here is some information about it:
"The compounds as sedative antihistamines can cause headache, sedation, somnolence, decreased psychomotor activity and anti-muscarinic effects (urinary retention, dry mouth, blurred vision, narrow-angle glaucoma and pyloroduodenal obstruction)."
I come very important to warn them about it, because someone may be in a situation similar to mine, and I saw people worrying too much about it.
Hello guys.. i have a question, i saw that you said the dosage was high.. so what is the best dosage after all? 25 pills on 50ml of water? or i should take alcohol instead of water? what kind of alcohol? i want to give it a try and post all my progress..
- - - Updated - - -
sorry for double post.. wait a minute, does not pge2 cause inflammation ? how can it help with hair growth? it's kind of contradictory
- - - Updated - - -
sorry for double post.. wait a minute, does not pge2 cause inflammation ? how can it help with hair growth? it's kind of contradictory
Chromeo
Established Member
- Reaction score
- 71
The dosage isn't too high. 60 tabs in 60ml of water is just fine. If anything, I'm thinking of maybe upping the dosage slightly to see if results get even better. As for an alcohol-based vehicle, judging from responses on here, you're more likely to see results if you use water and not alcohol.
I dunno about the PGE2 side of things, I am but a humble lab rat on this one...maybe one of the other guys will explain it. All I'm really bothered with is seeing results without sides, and so far so good.
I dunno about the PGE2 side of things, I am but a humble lab rat on this one...maybe one of the other guys will explain it. All I'm really bothered with is seeing results without sides, and so far so good.
I can't tell you guys what to do/not do. But be mindful of any changes that you may experience if your experimenting. Cetrizine is a prodrug that gets converted to hydroxyzine, which is an older class of antihistamines. And yes, if you have open angle glaucoma you should not be using this. Also, if you are on any other kind of immunosuppressive drugs, you should also not be on it. You should also not get any type of live vaccines since you can actually contract the disease. Antihistamines diminish your ability to fight infections. I don't know what dosage you guys are all taking or for how long, so I'm just throwing it out there.
Anti-histamine and corticosteroids have all long been known to increase hair growth( check on google for concussions of rogaine with betamethasone), this is already known and is def. not something new nor a cure. The problem is that you cannot be on them indefinitely because of the reasons I already stated, which is why drug companies haven't chosen to go down this path. People that HAVE to be on these because of allergies or other autoimmune disorders will tell you that there are definitely drawbacks, specially if you've been on the for a long duration of time.
- - - Updated - - -
Narrow/Closed angle glaucoma... Sorry about that
- - - Updated - - -
You may be asymptomatic right now, but it will defenitely affect you. If you plan on stopping this medication, please do so gradually since there is an increased risk of reflex reaction which causes you to become OVERsensetive if you have been on this for a while.
Anti-histamine and corticosteroids have all long been known to increase hair growth( check on google for concussions of rogaine with betamethasone), this is already known and is def. not something new nor a cure. The problem is that you cannot be on them indefinitely because of the reasons I already stated, which is why drug companies haven't chosen to go down this path. People that HAVE to be on these because of allergies or other autoimmune disorders will tell you that there are definitely drawbacks, specially if you've been on the for a long duration of time.
- - - Updated - - -
Narrow/Closed angle glaucoma... Sorry about that
- - - Updated - - -
You may be asymptomatic right now, but it will defenitely affect you. If you plan on stopping this medication, please do so gradually since there is an increased risk of reflex reaction which causes you to become OVERsensetive if you have been on this for a while.
Chromeo
Established Member
- Reaction score
- 71
Good to hear it is actually confirmed to increase growth, a lot of others seemed to doubt this for some reason. Seems it's been known for quite some time. Wish someone had told me a good ten years back...
The dangers to which Franky 69 is referring in regards to anti-histamines is most likely a problem when taken orally as that has always been the primary method of delivery. Although I'm not a expert, I really doubt that topical application could present these problems. In fact, I believe the problem is even having an effective enough delivery of cetirizine that even provides enough absorption to the scalp.
That's the million dollar question.. do we get any systemic absorption via topical route. I am in the camp that I do feel a bit fuzzy/spacey with the 1mg/1ml dosage. Others report the same. It could all be psychosomatic though. I've cut my mix to 5-7mg per 25ml. Seems to have eliminated the sides but maybe it was all in my head. WTF knows.
I definitely believe there has to be a systemic absorbtion when used topically. I stopped using for a couple days because I was getting bad headaches and felt tired and achey. As soon as I stopped applying I felt like I was back to normal.
Sparky4444
Senior Member
- Reaction score
- 44
no doubt it is getting in our systems....
rudimentary
Established Member
- Reaction score
- 9
I want to believe cetirizine works, I hope it does. I am going to get started on it soon.
Harry S Truman
Member
- Reaction score
- 2
of course it absorbs systemically
The skin does an excellent job in preventing things from being absorbed into your body. However, it all depends on the chemical/dosage/ and vehicle that you use. I would say that it definitely does get absorbed. The question is how much. There's no studies done on this, neither in vivo or in vitro. So its anyone guess at this point. I tried doing a research at my school on any type of articles and couldn't find anything for you guys.
Also, Cetrizine is a prodrug that gets converted to hydroxizine, which is an older class of anti-histamines --> more side effects. I would say see if you can talk to a Derm doctor/allergy doctor or some type of specialist , be honost about what your using and how your using it and see what they say. It can't hurt. I unfortunately don't have enough experience on this subject matter to help you any further.
Anti-histamines and corticosteroids are induce hair growth. But both cause alot of problems when used over a long period of time. Thats the problem. Whatever you use, you need to know that you can continue to use it over an extended period of time or else its pointless. Your only buying very little time if you have to drop this within 6 months to a year from now.
- - - Updated - - -
Please dont use corticosteroids topically for hair growth, that will def cause more problems than anti-histamines.
Also, Cetrizine is a prodrug that gets converted to hydroxizine, which is an older class of anti-histamines --> more side effects. I would say see if you can talk to a Derm doctor/allergy doctor or some type of specialist , be honost about what your using and how your using it and see what they say. It can't hurt. I unfortunately don't have enough experience on this subject matter to help you any further.
Anti-histamines and corticosteroids are induce hair growth. But both cause alot of problems when used over a long period of time. Thats the problem. Whatever you use, you need to know that you can continue to use it over an extended period of time or else its pointless. Your only buying very little time if you have to drop this within 6 months to a year from now.
- - - Updated - - -
Please dont use corticosteroids topically for hair growth, that will def cause more problems than anti-histamines.
rudimentary
Established Member
- Reaction score
- 9
franky69: I've actually spoken to my MD about the possibility of using cetirizine to get some regrowth in my temples. What he said to me is exactly your point. The long term use of anti-histamines is not good for the body, and yes, it does get absorbed by the skin and into your blood, even in small amounts.
What gives? Dammit.
What gives? Dammit.
casperz
Experienced Member
- Reaction score
- 25
The german user minox86 that showed the most success reported in Mid January that he had no overall cosmetic improvement as of yet but posted pictures clearly showing good regrowth. He is at 6 months.
The last picture is from October 2012 and the other three are mid January. He is seeing the same type of darking at the
base of the small hairs that I'm seeing. You will also notice several double hairs in the #3 picture. I think pic #1 shows
much stronger hairs than the October pic.
I'm still hopeful that we are on to something but it is a SLOW process.
The last picture is from October 2012 and the other three are mid January. He is seeing the same type of darking at the
base of the small hairs that I'm seeing. You will also notice several double hairs in the #3 picture. I think pic #1 shows
much stronger hairs than the October pic.
I'm still hopeful that we are on to something but it is a SLOW process.
Attachments
Sparky4444
Senior Member
- Reaction score
- 44
I'll betcha dimes to dollars that if you were to rub in castor oil as well, you'd see things jump faster..
...i'm off of the CET thing....too light-headed from this stuff...plus I am a diffuse thinner so my faith will have to be in DHT blocking ala non finasteride ...