Hi! I am a regular visitor of heralopecia. But I had a quick question. In this excerpt re. drug induced hair loss, spironolactone is mentioned. What is the mechanism by which it can CAUSE hair loss. (I am aware that it is an antiandrogen that competes with andros. at receptor sites.) Here is the excerpt from the HairLossTalk.com library:
Thanks so much!!
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November 29, 2002
A new article was printed in the LA times giving a great overview of several products which can cause hair loss. This article is especially relevant to women, as a large percentage of female hair loss is due to what we prefer to call “external reasonsâ€...
Medications, pregnancy, hormonal imbalances, etc. are more often than not the culprit. Men on certain medications can also experience drug induced hair loss as well however. Among the many drugs known to cause hair loss, Antidepressants are one of the most common that actually *do* result in noticeable thinning on a frequent basis. Likewise, in the "high risk" zone for hair loss as a side effect, any drugs that directly affect the hormonal system of the user (birth control pills, steroids, etc) can cause hair loss.
A QuickList
The following is a list of ingredients, medications, drugs, and compounds that have a high reputation for causing hair loss when taken in excess, and sometimes when taken (or experienced) in moderation. This list is by no means all-inclusive, but its a helpful start. If you feel you are experiencing hair loss due to any external factors, discuss it with your physician.
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allopurinol, arsenic, apirin, l-asparaginase, bismuth, bleomycin, boric acid, bromocriptine, carbamazepine, carbon monoxide, chlorambucil, chloramphenicol, cimetidine, colchicine, clofibrate, clomiphene citrate, coumarin anticoagulant, cyclophosphamide, cyproterone acetate, dactinomycin, danazol, diethyl carbamazepine, dipyridamole, doxorubicin, ethionamide, etoposide, etretinate, fenifibrate, gentamycin sulphate, guanethidine, heparin (telogen effluvium after 6-16 weeks ), hydroxychloroquine, ibuprofen, idoxuridine, indandione, indomethacin, interferon, iodine, isophosphamide, levamisole, levodopa, lithium, mepacrine, mercury, mesalazine, methisazone, methotrexate, methyl CCNU, methysurgide, metoprolol, mitomycin, mitrexantrone, morphine, nadolol, nafoxidine, nicotinic acid, nicotinyl alcohol, nitrofurantoin sodium, norethisterone, estrogens, oral contraceptives, para aminosalicylate, phenindione, phenprocoumon, potassium thiocyanate, procainamide, propanolol, selenium sulphide, sodium aurothiomalate, sodium valproate, spironolactone, sulphasalazine, tamoxifen, thalium acetate, thiamphenicol, terfenadine, trimethadione, troxidone, vasopressin, vincristine, vindesine, vitamin A, warfarin
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Thanks so much!!
--------------------------------------------------------------------------------
November 29, 2002
A new article was printed in the LA times giving a great overview of several products which can cause hair loss. This article is especially relevant to women, as a large percentage of female hair loss is due to what we prefer to call “external reasonsâ€...
Medications, pregnancy, hormonal imbalances, etc. are more often than not the culprit. Men on certain medications can also experience drug induced hair loss as well however. Among the many drugs known to cause hair loss, Antidepressants are one of the most common that actually *do* result in noticeable thinning on a frequent basis. Likewise, in the "high risk" zone for hair loss as a side effect, any drugs that directly affect the hormonal system of the user (birth control pills, steroids, etc) can cause hair loss.
A QuickList
The following is a list of ingredients, medications, drugs, and compounds that have a high reputation for causing hair loss when taken in excess, and sometimes when taken (or experienced) in moderation. This list is by no means all-inclusive, but its a helpful start. If you feel you are experiencing hair loss due to any external factors, discuss it with your physician.
--------------------------------------------------------------------------------
allopurinol, arsenic, apirin, l-asparaginase, bismuth, bleomycin, boric acid, bromocriptine, carbamazepine, carbon monoxide, chlorambucil, chloramphenicol, cimetidine, colchicine, clofibrate, clomiphene citrate, coumarin anticoagulant, cyclophosphamide, cyproterone acetate, dactinomycin, danazol, diethyl carbamazepine, dipyridamole, doxorubicin, ethionamide, etoposide, etretinate, fenifibrate, gentamycin sulphate, guanethidine, heparin (telogen effluvium after 6-16 weeks ), hydroxychloroquine, ibuprofen, idoxuridine, indandione, indomethacin, interferon, iodine, isophosphamide, levamisole, levodopa, lithium, mepacrine, mercury, mesalazine, methisazone, methotrexate, methyl CCNU, methysurgide, metoprolol, mitomycin, mitrexantrone, morphine, nadolol, nafoxidine, nicotinic acid, nicotinyl alcohol, nitrofurantoin sodium, norethisterone, estrogens, oral contraceptives, para aminosalicylate, phenindione, phenprocoumon, potassium thiocyanate, procainamide, propanolol, selenium sulphide, sodium aurothiomalate, sodium valproate, spironolactone, sulphasalazine, tamoxifen, thalium acetate, thiamphenicol, terfenadine, trimethadione, troxidone, vasopressin, vincristine, vindesine, vitamin A, warfarin
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