I don't know if they make each other ineffective but I use Crinagen and I follow this rule.
Apply Crinagen and then at least 15-20 minutes later (preferably longer) put minoxidil. minoxidil takes much longer to absorb. At least 4 hours.
So it makes sense to apply first other stuff.
And that’s what Dr. Raztec (maker of Crinagen) recommends.
p.s. I heard something about Zinc and minoxidil making each other ineffective, but I cannot remeber for sure.