This Paper Has Some Interesting Data About Estrogen In Androgenetic Alopecia

mr_robot

Experienced Member
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Regarding S-Equol, if you look at the brotzu patent and accept that the amount of S-Equol is correct it looks like the dose is only 0.2mg per 1ml daily dose.

I've been extracting S-Equol from four crushed Equelle tablets for nearly a year now at 1.42mg (assuming 100% extraction) and recently upped the dosage to what would be 3.57mg a day topically. I can't say that it has had a magical effect athough I can't even be certain that my extraction S-Equol is working.
 
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whatevr

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AR Antagonists such as CB have proven to be effective, on their own, in clinical trials. Whether this method affects Estrogen receptor alpha or beta in the same way that estrogen seems to modulate AR remains to be confirmed. Regardless, they do work, no S-equol needed. It's only needed if it provides better results or is safer, and at this point it's hard to make a 1:1 comparison of the two.

Clinical trials also suggest a very low incidence of side effects for drugs like Finasteride and Dutasteride, yet here we are, the forums are full of them.

I'm asking where are the real world results with people using drugs like RU? I understand that CB is expensive and no one has trialed it properly, but I have yet to see a single long term success story of someone maintaining using just RU which is also a stronger AR antagonist than CB will be.

Finasteride with its reduction of total and scalp DHT has far more of a proven track record simply because by removing DHT it prevents hair interruption through both the AR and the ER. S-Equol could potentially allow us to do this topically.
 
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