the most potent anti androgen or dht blocker

[ukmale24]

If you looked at my regimen, you'd see i don't use finasteride, i'm mostly anti-finasteride because of the risk of sides but i have been considering it.

Fair enough though, i stand corrected, i didn't see where you'd written that finasteride doesn't stop working after 2 years.

However, it sounds as though there's no topical DHT inhibitors out there that make a difference, certainly none with even a quarter effectiveness as oral finasteride, or with the same cost.

 

[Bryan]

Bryan is saying, although it may lose it's initial effectiveness, it still works to a degree where you lose less hair but not as much as if you didn't take it all, right?

Yea, and I'm saying that why use a drug that starts to lose power after a period # of years when there are topical DHT inhibitors that continue to work as long as you use it without decline?

Oh, you think there are topical "DHT inhibitors" [sic] that were tested for male pattern baldness in just as careful and precise a fashion as finasteride was tested for male pattern baldness by Merck, and found to work even better than Propecia? You're dreaming, friend. I suspect that any topical 5a-reductase inhibitor would probably have the same long-term effect on haircounts as Propecia did (a slight decline in haircounts, after the peak at one or two years). In any event, there's no point in even making such a claim, without actually testing it first, to see what happens in that regard.

These are not accurate statements. It implies after 2 years the drug stops working, which is clearly not the case.

You need to read everything I wrote out. I made sure everyone knew that I did not imply with those statements the way you say I mean. If I meant that when I said that then I would make it clear right now.

I think it's clear what you were saying during your original posts that Propecia "dies off" after the first two years. I give you credit, though, for realizing the error of your ways, and considerably modifying such a false and egregious claim.

I also think it's "laughable" that these comments are coming from Propecia users.

I'm not a Propecia user. I've never taken a molecule of finasteride in my entire life.

 

[John979]

UKmale;

What do you mean by a topical DHT inhibitor? Regarding your comment that none exist, the jury is out on Eucapil, and Ketoconazole is more effective than many think.

I say this time and time again, there is some evidence that low dose topical dutasteride is under-appreciated, especially since a little may go a long way and it is easy to obtain.

What do you have to lose? I month's oral supply of 30 gel caps (0.5 mg) will last 4 months at 0.25 mg every other day and perhaps even that dose is a bit too high.

 

[ukmale24]

I use Keto shampoo, and occasionally applied keto cream. Has topical dutasteride done anything for you? How do you apply it topically?

 

[Rocky V]

I use Keto shampoo, and occasionally applied keto cream. Has topical dutasteride done anything for you? How do you apply it topically?

how has keto cream been for you?

 

[ukmale24]

rubbish. just aggravates my skin, although i'm sure it's something you probably have to use every day or two days for a period over 3-6 months to see anything.

 

[Rocky V]

how often do you use it? did it stop or slow down your hairloss?

 

[Rutt]

I cannot believe you guys didn't pick up on the fact that finasteride DOESNT INHIBIT ALL YOUR DHT. It blocks ~85%. That's still 15% or 1/7th left. Thats why it trends back towards the baseline slowly, although in some men 1/7th is enough!

If you think the 15% could be an issue, use dutasteride since it blocks ~98%.

 

[John979]

Rutt;

Technically, neither finasteride nor dutasteride inhibits DHT. They block the action of the enzyme that converts T to DHT.

Therein lies the problem. For some men, it does appear that DHT needs to be "inhibited" nearly 100% and that may not be achieved without significant side effects and risks.

A good discussion point too is circulating DHT. Studies are equivocal regarding its contribution to hair loss, as are studies regarding Type I 5-Apha's contribution to hair loss, as this enzyme is not blocked by finasteride.

I have said this many times, I saw no appreciable gains of any kind until I stated a combination of topical Dutasteride and 2% Keto. I needed to stop minoxidil due to side effects and had some regression that appears to have been reversed by Bimatoprost. This was recently supplemented with Eucapil.

And I don't use too much Dutasteride. Only 0.20 mg every other day.

 

[John979]

Rutt;

Technically, neither finasteride nor dutasteride inhibits DHT. They block the action of the enzyme that converts T to DHT.

Therein lies the problem. For some men, it does appear that DHT needs to be "inhibited" nearly 100% and that may not be achieved without significant side effects and risks.

A good discussion point too is circulating DHT. Studies are equivocal regarding its contribution to hair loss, as are studies regarding Type I 5-Apha's contribution to hair loss, as this enzyme is not blocked by finasteride.

I have said this many times, I saw no appreciable gains of any kind until I stated a combination of topical Dutasteride and 2% Keto. I needed to stop minoxidil due to side effects and had some regression that appears to have been reversed by Bimatoprost. This was recently supplemented with Eucapil.

And I don't use too much Dutasteride. Only 0.20 mg every other day.

 

[ukmale24]

how often do you use it? did it stop or slow down your hairloss?

I don't use it, i've used it about 5 times, not really enough for me to make a claim it counters hair loss, lol.

 

[Bryan]

Technically, neither finasteride nor dutasteride inhibits DHT. They block the action of the enzyme that converts T to DHT.

I _do_ recommend that people use the same terms that doctors and scientists use in professional journals. The term "DHT inhibitor" is just a bastardization used by people on hairloss forums. Doctors and scientists don't say that! They say "5a-reductase inhibitor".

 

[Infinity95]

Nice thread!

 

[abcdefg]

Yeah although bryan argued some stuff relentlessly he had a lot of good points and knew a lot about male pattern baldness. He would always correct people when they spouted non sense as happens so often on the forums

 

[g.i joey]

rip to bryan, when i first noticed hairloss, i would seek his opinion for approval on everything i was researching, sucks we dont have such a reputable person on these forums anymore.