This is what we've been waiting for. Can anyone decifer this for us? Doctor?
The top 30 upregulated genes in balding dermal papilla cells in response to 100 nM DHT determined by microarray hybridization.
Gene ................ Genebank ID............ Fold increase
tyrosyl-tRNA synthetase (YARS) NM_003680 5.07
dickkopf homolog 1 (DKK1) NM_012242 4.64
serum/glucocorticoid regulated kinase (SGK) NM_005627 4.53
a disintegrin-like and metalloprotease (ADAMTS5) NM_007038 3.75
solute carrier family 19 (SLC19A2) NM_006996 3.31
solute carrier family 2 (SLC2A3) NM_006931 2.99
H2A histone family, member Z (H2AFZ) NM_002106 2.86
RING1 and YY1 binding protein (RYBP) NM_012234 2.75
nuclear receptor coactivator 3 (NCOA3) NM_181659 2.63
adenosylmethionine decarboxylase 1 (AMD1) NM_001634 2.46
LPS-induced TNF-alpha factor (LITAF) NM_004862 2.36
ornithine decarboxylase 1 (ODC1) NM_002539 2.34
myeloid cell leukemia sequence 1 (MCL1) NM_182763 2.32
ATPase family homolog up-regulated in senescence cells (AFURS1) NM_024524 2.31
ADP-ribosylation factor-like 4C (ARL4C) NM_005737 2.3
cyclin-dependent kinase inhibitor 1A (p21) (CDKN1A) NM_000389 2.3
aldo-keto reductase family 1, member C1 (AKR1C1) NM_001353 2.29
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 (DDX5) NM_004396 2.27
fibroblast growth factor 7 (FGF7) NM_002009 2.26
solute carrier family 3 (SLC3A2) NM_002394 2.22
VAMP-associated membrane protein B (VA0AP) NM_003574 2.1
HSPC048 protein (HSPC048) NM_014148 2.09
syndecan binding protein (syntenin) (SDCBP) NM_005625 2.08
matrix metalloproteinase 3 (MMP3) NM_002422 2.08
cyclin-dependent kinase inhibitor 1A (p21) (CDKN1A) NM_078467 2.07
Kruppel-like factor 10 (KLF10) NM_005655 2.02
heme oxygenase (decycling) 1 (HMOX1) NM_002133 2.02
UDP-glucose ceramide glucosyltransferase (UGCG) NM_003358 2.01
solute carrier family 7 (SLC7A5) NM_003486 1.99
transforming growth factor, beta 2 (TGFB2) NM_003238 1.98
The top 30 upregulated genes in balding dermal papilla cells in response to 100 nM DHT determined by microarray hybridization.
Gene ................ Genebank ID............ Fold increase
tyrosyl-tRNA synthetase (YARS) NM_003680 5.07
dickkopf homolog 1 (DKK1) NM_012242 4.64
serum/glucocorticoid regulated kinase (SGK) NM_005627 4.53
a disintegrin-like and metalloprotease (ADAMTS5) NM_007038 3.75
solute carrier family 19 (SLC19A2) NM_006996 3.31
solute carrier family 2 (SLC2A3) NM_006931 2.99
H2A histone family, member Z (H2AFZ) NM_002106 2.86
RING1 and YY1 binding protein (RYBP) NM_012234 2.75
nuclear receptor coactivator 3 (NCOA3) NM_181659 2.63
adenosylmethionine decarboxylase 1 (AMD1) NM_001634 2.46
LPS-induced TNF-alpha factor (LITAF) NM_004862 2.36
ornithine decarboxylase 1 (ODC1) NM_002539 2.34
myeloid cell leukemia sequence 1 (MCL1) NM_182763 2.32
ATPase family homolog up-regulated in senescence cells (AFURS1) NM_024524 2.31
ADP-ribosylation factor-like 4C (ARL4C) NM_005737 2.3
cyclin-dependent kinase inhibitor 1A (p21) (CDKN1A) NM_000389 2.3
aldo-keto reductase family 1, member C1 (AKR1C1) NM_001353 2.29
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 (DDX5) NM_004396 2.27
fibroblast growth factor 7 (FGF7) NM_002009 2.26
solute carrier family 3 (SLC3A2) NM_002394 2.22
VAMP-associated membrane protein B (VA0AP) NM_003574 2.1
HSPC048 protein (HSPC048) NM_014148 2.09
syndecan binding protein (syntenin) (SDCBP) NM_005625 2.08
matrix metalloproteinase 3 (MMP3) NM_002422 2.08
cyclin-dependent kinase inhibitor 1A (p21) (CDKN1A) NM_078467 2.07
Kruppel-like factor 10 (KLF10) NM_005655 2.02
heme oxygenase (decycling) 1 (HMOX1) NM_002133 2.02
UDP-glucose ceramide glucosyltransferase (UGCG) NM_003358 2.01
solute carrier family 7 (SLC7A5) NM_003486 1.99
transforming growth factor, beta 2 (TGFB2) NM_003238 1.98