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the European Commission officially issued the Regulation (EU) 2021/1902 Regulation Bulletin, which revised the list of prohibited ingredients in Annex II of the European Cosmetics Regulations. The anti-dandruff agent Zinc Pyrithione (ZPT) was added due to its reproductive toxicity 1B of GHS classification. The cosmetic anti-dandruff agent ZPT is officially banned in EU cosmetics since March 1, 2022.