- Reaction score
- 686
I visited the biotechnological faculty of the university i am currently working at. Here are some information regarding stem cells in general and regarding hairloss.
Normal cells can be turned into stem cells since 2014 and it is allready state of the art teaching. This cells indeed are more likely to evelop tumorgenesis. (This is an approach used by alexey)
Cartilage like hair is very hard to recreate. One methode to do so is to make a whole in the nearest bone and let the bone marrow partially bleed out. The stem cells in the bone marrow can recreate the cartilage if there is still some cartilage left. The bone marrow is also the reason why bones can heal after breaking. The bone marrow goes out and the stem cells create new bone tissue.
(I asked if this technic could be used for hairloss.)
The stem cells mimic the behavior of the surounding cells. That means if the are applied to a follicle the can strengthen it and repair it if there are enough cells left which the stem cells can mimic.
Another problem is nobody would allow to extract bone marrow to cure hairloss.
I also asked about shiseido/replicel riken and follica. He was only aware of riken (because of the organ and teeth regeneration) the other he never heard of. I explained their technologies and here is his opinion.
Follica:
He is no expert in hair follicle. But from his understanding if they archieve neogenesis. The neogenesis should only take place in areas where are some hairs or at least dormant follicles. So if a Norwood 7 whos follicles are all really dead he would slowly create hair at the edge of the horseshoe which leads to an increasing horseshoe til the whole head is covered. (But he explicitly told me that this is an educated guess and for better information I should speak to someone who is more related to the hair subject.)
replicel/shiseido:
He thinks the claim that this treatment makes the hair imune or even more resistant to dht is very unlikely. The stem cells mimic the surounding cells. so the stem cells do not really have a codesequence that makes the hair follicle in the donor area dht resistant. But he said the stem cells repair the follicle and giving the their originally strength. So they can survive the attacks of dht and need to be repaired after a few years. So with an injecton every few years it has the same effect as if the follicle would be resistant to dht.
riken:
After he saw the pictures of the mouse with human hair and after we went through the last statement of rken he said they are through with the science. In his opinion tsuji can only fail if their protocoll somehow favor tumorgenesis. Which he thinks is very unlikely.
(I asked him how long the trials will take)
He could not even give an educated guess since he does not know the protocoll and the regulations.
(same holds for prices etc)
Normal cells can be turned into stem cells since 2014 and it is allready state of the art teaching. This cells indeed are more likely to evelop tumorgenesis. (This is an approach used by alexey)
Cartilage like hair is very hard to recreate. One methode to do so is to make a whole in the nearest bone and let the bone marrow partially bleed out. The stem cells in the bone marrow can recreate the cartilage if there is still some cartilage left. The bone marrow is also the reason why bones can heal after breaking. The bone marrow goes out and the stem cells create new bone tissue.
(I asked if this technic could be used for hairloss.)
The stem cells mimic the behavior of the surounding cells. That means if the are applied to a follicle the can strengthen it and repair it if there are enough cells left which the stem cells can mimic.
Another problem is nobody would allow to extract bone marrow to cure hairloss.
I also asked about shiseido/replicel riken and follica. He was only aware of riken (because of the organ and teeth regeneration) the other he never heard of. I explained their technologies and here is his opinion.
Follica:
He is no expert in hair follicle. But from his understanding if they archieve neogenesis. The neogenesis should only take place in areas where are some hairs or at least dormant follicles. So if a Norwood 7 whos follicles are all really dead he would slowly create hair at the edge of the horseshoe which leads to an increasing horseshoe til the whole head is covered. (But he explicitly told me that this is an educated guess and for better information I should speak to someone who is more related to the hair subject.)
replicel/shiseido:
He thinks the claim that this treatment makes the hair imune or even more resistant to dht is very unlikely. The stem cells mimic the surounding cells. so the stem cells do not really have a codesequence that makes the hair follicle in the donor area dht resistant. But he said the stem cells repair the follicle and giving the their originally strength. So they can survive the attacks of dht and need to be repaired after a few years. So with an injecton every few years it has the same effect as if the follicle would be resistant to dht.
riken:
After he saw the pictures of the mouse with human hair and after we went through the last statement of rken he said they are through with the science. In his opinion tsuji can only fail if their protocoll somehow favor tumorgenesis. Which he thinks is very unlikely.
(I asked him how long the trials will take)
He could not even give an educated guess since he does not know the protocoll and the regulations.
(same holds for prices etc)
