Use it in conjunction with Nizoral, I'm going to assume you know what that is, twice to three times a week. You don't need to take any supplements but if you wish, start 25mg of Zinc a day, costs like €7 in a chemist. The reason people take zinc is to "stop", for lack of a better word, excess testosterone from converting into oestrogen.
Take your pill whenever you want, be patient, a year to 18 months and I'm sure you'll see improvement. Good luck.