Sprirolactone 5% cream.

decro435

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Has anyone here taken spironolactone 5% cream for the long term (i.e 1-3 years?) I want to incorparate it into my regimen full time but I'm afraid of what it could do in the long run.

1. Are there any side-effects from topical Sprirolactone 5% cream?

2. Is there any systemic absorbtion?

3. When applying it wouldn't it get absorbed through your hands?

5. What is its purpose? To destroy DHT on the scalp?

6. Is it effective on its own without finasteride? If not , why not?

7. Has anyone seen any results they can actually confirm that spironolactone has actually done on its own?
 

Fundi

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decro435 said:
Has anyone here taken spironolactone 5% cream for the long term (i.e 1-3 years?) I want to incorparate it into my regimen full time but I'm afraid of what it could do in the long run.

1. Are there any side-effects from topical Sprirolactone 5% cream?

2. Is there any systemic absorbtion?

3. When applying it wouldn't it get absorbed through your hands?

5. What is its purpose? To destroy DHT on the scalp?

6. Is it effective on its own without finasteride? If not , why not?

7. Has anyone seen any results they can actually confirm that spironolactone has actually done on its own?

1. Apparently some get a mild rash, one or two experienced mild chest pain when they over did it, but it went away with a normal amount

2. Apprently not. - I've experienced nothing to suggest that it is...no sides and nothing like the sides from oral spironolactone

3. Don't know.

5. Prevents the synthesis of DHT, Blocks the receptor sites at the scalp, and converts testorone in the scalp to estrogen.

6. Topicals generally aren't. But just like finasteride, some get results, some don't.

7. There's was a study (Italian I think) which showed improvement in hair using spironolactone alone. I've seen some good results here (With minoxidil though)
 

Bryan

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SoThatsLife

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Bryan, is there a index page on your site? I know you have a lot of studies on your page, but its impossible to see them if one don't have the right url.
 

decro435

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Byran , cheers for the information. By the looks of it spironolactone is an effective treatment in slowing down male pattern baldness , but does not seem to cause any regrowth which is exactly how I expected. IT was Byran what is your conclusion?
 

Bryan

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SoThatsLife said:
Bryan, is there a index page on your site? I know you have a lot of studies on your page, but its impossible to see them if one don't have the right url.

I don't have an index page for all those scans because it's just a simple, free, Geocities account. If people started downloading everything I have on there willy-nilly, it would quickly exhaust the relatively limited bandwidth they provide for their free accounts, making it go into that "waiting" mode where people have to wait for another hour or so to start getting downloads again.

Because of those severe limitations, I generally just provide a link or two at a time, whenever the need arises as I'm posting on hairloss sites. I figure (at least, I hope) that people won't overwhelm the system too much if I only post a link like that occasionally! :)
 

Bryan

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decro435 said:
Byran , cheers for the information. By the looks of it spironolactone is an effective treatment in slowing down male pattern baldness , but does not seem to cause any regrowth which is exactly how I expected. IT was Byran what is your conclusion?

Oh, I conclude that topical spironolactone is probably helpful for fighting male pattern baldness, if you apply it consistently. But like so many other topicals, it's messy and can even be smelly at times. I wish we had more effective topical antiandrogens easily available (like RU58841), but we don't. We have to make do with what we have.
 

Fundi

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amsch said:
Bryan said:
Here's a scan of the full Italian study of topical spironolactone for male pattern baldness:

http://www.geocities.com/bryan50001/spiro2.htm
Is it possible that the 2nd guy's here looks more receded in the after pic?


Obviously the pics are crap, but his left temple certainly looks much better. The right, pretty much the same. - If that's the case it's maintained for at least 12 months which is relatively impressive - They only used a 3% solution.

I've used minoxs - Fine in terms of smell and stuff. Not sure about results, only used for a month.

Has anyone used the 5% spironolactone cream from this site? It has azelic acid and caffeine in and seems a bit cheaper so why does everyone seem to use minoxidil.com?
 

decro435

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I get a allergic reaction from azeliac acid , thats why. Has anyone here ever got any side effects from spironolactone 5% cream?

I know the study says it won't produce side effects , but I know full well that some of these studies are untrue , especially the 2% side effect sufferers with Propecia.
 

Petchsky

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Just to add, Azeleic acid is also an anti androgen, along with rosemary.
 
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