So What Is The Difference Between Finasteride 1 Mg And 5 Mg?

[michel sapin]

Given the fact that 5 mg and 1 mg inhibit the same amount of dht . even 0,5 mg inhibit the same .
Why do the give 5 mg for bph and 1 mg for hairloss ?
Is it a marketing strategy?

 

[michel sapin]

any opinion

 

[KO21]

I would think hair can only benefit so much from finasteride but 5mg could benefit bph in other ways

 

[michel sapin]

so basically all the dosage from 0,5mg to 5 mg cause the same side ?
microdosing fina in order to reduce side is useless

 

[shulk]

Thats why 0,5mg is not considered microdosing.

Is the DHT inhibition of 1mg and 5mg the same on prostate levels? I reckon you are looking at Serum DHT, possibly it is not 1:1. Scalp and Serum DHT are not. So possibly dosage could correlate to prostate size. I don't know .

 

[horunger]

I think a common misunderstanding is that a 65% DHT reduction is almost as good as a 70% reduction, from the perspective of a human brain the numbers are close and 65 seems acceptable.

Remember that regrowth numbers are average across several patients, expect there to be several persons with zero regrowth on 1mg who disappear in the statistics, by going for a low dosage you could be one of them. We see lots of people who mis-use these numbers to conclude that "0.1 mg Fina is good enough", they forget the statistics contain people who has no growth at any dosage, and people who report increased dht levels when taking it. To counter for unknown factors its safest to go for a moderate to high dose, dont do the mistake of placing yourself right bang in the middle of any statistics, leave some slack for individual variations, if your shoes are one size too big you can tighten the laces but if they are a size too small youre pretty much screwed.

 

[horunger]

Thats why 0,5mg is not considered microdosing.

Is the DHT inhibition of 1mg and 5mg the same on prostate levels? I reckon you are looking at Serum DHT, possibly it is not 1:1. Scalp and Serum DHT are not. So possibly dosage could correlate to prostate size. I don't know .

Most of your reasoning is very good, still i cant help but feeling your approach is too pedantic, we already know dht reduction on fina is extremely individual, some even see a dht increase, there is no way to correlate inhibition data with prostate size even if we all went and had our prostates measured with ultrasound.

 

[michel sapin]

k so that means you could have more regrowth with 5 mg fina than 1 mg? or better maintenance?

 

[horunger]

k so that means you could have more regrowth with 5 mg fina than 1 mg? or better maintenance?

Better chances at least. When starving to death we can extend life for a very long time by eating just a very little meal every day but its not a desirable situation, obviously more is better. I dont support the idea of aiming for minimums, or the mildest drug, if prostate patients need 5mg to remove dht then y d fukk would it be different for hair? Microdosers has no chance in the long term, in fact the failure rate on long term finasteride users is big enough to cause concern even on normal doses. Maybe its time to ask before/after photos from successful microdosers after 5 to 10 years. My oldest bro was on low dose but not seriously low and even though he retained some into his 40ies the battle was lost already 10 years earlier. Most guys need something that will last for 40 years, and we cant even see a 10 years success from microdosers.

 

[michel sapin]

k so according to you if propecia 1 mg failed to maintain, maybe 5 mg can do the trick? Instead of switching to duta

 

[Zoro]

Better chances at least. When starving to death we can extend life for a very long time by eating just a very little meal every day but its not a desirable situation, obviously more is better. I dont support the idea of aiming for minimums, or the mildest drug, if prostate patients need 5mg to remove dht then y d fukk would it be different for hair? Microdosers has no chance in the long term, in fact the failure rate on long term finasteride users is big enough to cause concern even on normal doses. Maybe its time to ask before/after photos from successful microdosers after 5 to 10 years. My oldest bro was on low dose but not seriously low and even though he retained some into his 40ies the battle was lost already 10 years earlier. Most guys need something that will last for 40 years, and we cant even see a 10 years success from microdosers.

The difference in scalp dht between 1mg and 5mg is only about 5%, not enough to save you if the 1mg isn't doing anything imo

https://www.ncbi.nlm.nih.gov/pubmed/10495374

Better off switching to dutasteride or combining it with RU than upping your dosage

 

[abcdefg]

I mean 1mg was found to be the optimal dose to maximize hair counts. Not a lot else to say that is why they approved it at 1mg for hair loss and not some other dose. 5mg was for a completely different condition.
1mg and 5mg dont inhibit the same amount of DHT it might not be a big difference but every difference matters. The studies they did showed those as the best doses.

 

[FBP]

Given the fact that 5 mg and 1 mg inhibit the same amount of dht . even 0,5 mg inhibit the same .
Why do the give 5 mg for bph and 1 mg for hairloss ?
Is it a marketing strategy?

smaller prostate. j/k .5mg-1.5mg only showed single digit increase in dht blocking if I can remember. So yah difference but not 1+1=2 type of difference