michael barry
Senior Member
- Reaction score
- 12
Selenium is a Prostaglandin D2 inhibitor, and in light of the Costarialis patent, I thought it would be interesting to view the effects on hair growth in some little in vivo test or another. It appears that either too little selenium or too much selenium is deleterious to hair. So a selenium sulfide shampoo used once or twice a week might be useful to hair. A salyicic acid shampoo might be useful in the same way since its upstream of all prostaglandins. However, some prostalgandins are purportedly good for hair and not bad for it.........................prostaglandin D2 apparently is for the most part bad, but some minimum level of it (hair follicles contain a PGD2 receptor) might be necessary-----who knows.
Titre du document / Document title
Primary hair growth in dogs depends on dietary selenium concentrations
Auteur(s) / Author(s)
YU S. ; WEDEKIND K. J. ; KIRK C. A. ; NACHREINER R. F. ;
Résumé / Abstract
Selenium (Se) plays an important role in hair growth. The objective of this study was to investigate the effect of dietary selenium concentration on hair growth in dogs. Thirty-six beagles were stratified into six groups based on age, gender and body condition score. The dogs were fed a torula yeast-based canned food for 3 weeks. Then the dogs were fed varying amounts of selenium supplied as selenomethionine for an additional 24 weeks. Analysed selenium concentrations in the experimental foods for the six groups were 0.04, 0.09, 0.12, 0.54, 1.03 and 5.04 mg/kg dry matter respectively. Body weight and food intake were not affected by the selenium treatments. Serum selenium concentration was similar Initially but was significantly different at the end of the study among groups. Dietary selenium concentration below 0.12 mg/kg diet may be marginal for an adult dog. Dietary treatment had no effect on serum total thyroxine (TT[4]), free thyroxine (FT[4]), and free 3,3',5-triiodothyronine (FT[3]). There was a significant diet and time interaction (p = 0.038) for total 3,3', triiodothyronine (TT[3]). Hair growth was similar among groups initially but significantly reduced in dogs fed diets containing 0.04, 0.09 or 5.04 mg Se/kg when compared with 0.12, 0.54 and 1.03 mg Se/kg at week 11 (p < 0.05) and week 22 (p = 0.061). These results demonstrated that both low and high selenium diets reduce hair growth in adult dogs.
Revue / Journal Title
Journal of animal physiology and animal nutrition (J. anim. physiol. anim. nutr.) ISSN 0931-2439
Source / Source
2006, vol. 90, no3-4, pp. 146-151 [6 page(s) (article)]
Langue / Language
Anglais
Revue : Multilingue
Editeur / Publisher
Blackwell, Berlin, ALLEMAGNE (1986) (Revue)
Localisation / Location
INIST-CNRS, Cote INIST : 768, 35400013553921.0060
Copyright 2007 INIST-CNRS. All rights reserved
Titre du document / Document title
Primary hair growth in dogs depends on dietary selenium concentrations
Auteur(s) / Author(s)
YU S. ; WEDEKIND K. J. ; KIRK C. A. ; NACHREINER R. F. ;
Résumé / Abstract
Selenium (Se) plays an important role in hair growth. The objective of this study was to investigate the effect of dietary selenium concentration on hair growth in dogs. Thirty-six beagles were stratified into six groups based on age, gender and body condition score. The dogs were fed a torula yeast-based canned food for 3 weeks. Then the dogs were fed varying amounts of selenium supplied as selenomethionine for an additional 24 weeks. Analysed selenium concentrations in the experimental foods for the six groups were 0.04, 0.09, 0.12, 0.54, 1.03 and 5.04 mg/kg dry matter respectively. Body weight and food intake were not affected by the selenium treatments. Serum selenium concentration was similar Initially but was significantly different at the end of the study among groups. Dietary selenium concentration below 0.12 mg/kg diet may be marginal for an adult dog. Dietary treatment had no effect on serum total thyroxine (TT[4]), free thyroxine (FT[4]), and free 3,3',5-triiodothyronine (FT[3]). There was a significant diet and time interaction (p = 0.038) for total 3,3', triiodothyronine (TT[3]). Hair growth was similar among groups initially but significantly reduced in dogs fed diets containing 0.04, 0.09 or 5.04 mg Se/kg when compared with 0.12, 0.54 and 1.03 mg Se/kg at week 11 (p < 0.05) and week 22 (p = 0.061). These results demonstrated that both low and high selenium diets reduce hair growth in adult dogs.
Revue / Journal Title
Journal of animal physiology and animal nutrition (J. anim. physiol. anim. nutr.) ISSN 0931-2439
Source / Source
2006, vol. 90, no3-4, pp. 146-151 [6 page(s) (article)]
Langue / Language
Anglais
Revue : Multilingue
Editeur / Publisher
Blackwell, Berlin, ALLEMAGNE (1986) (Revue)
Localisation / Location
INIST-CNRS, Cote INIST : 768, 35400013553921.0060
Copyright 2007 INIST-CNRS. All rights reserved