Hi, I use a 0.25mg EOD, 0.05mg topical finasteride daily + minoxidil, and used to do 12.5 - 15mg RU58841 daily (until 2 days ago). I've seen people use up to RU58841 50mg, 100mg a day. I used RU this way for maybe 1.5 months, and during the last week, I felt more lerthargic, heart felt heavier, and 2 days ago, I was complete exhausted and couldn't run for a sustained period. I know it seems like I am imagining because I was using RU for a long time with no observed sides, but the effects were similar to an earlier time when I crashed after over-using RU for a period. I am planning to get back onto RU, to see once more if the effect was from that. Does anyone have an experience of RU for a long period and then having a sudden crash within a week? Does this make any scientific sense? Also, could RU work at the low doses I am using?