RU 58841

soulsurvivor316 · Jan 11, 2005

*Please don't move this to the experimental treatments section*

Have there been any more developments with this product? I know there were human trials being conducted and if I remember correctly, a poster on here got excellent results from this. Does anyone have any info on this product? Is there any way we can get it? Does it look like its going to be safe? How does it compare to what we have right now? My knowledgeable people, get at me.

Rawbbie · Jan 11, 2005

what in the world are you talking about

oni · Jan 12, 2005

RU 56187 and RU 58841.

New antiandrogen with nonsteroid structure. They are N-substituted arylthiohydantoins.

Mechanism:
Inhibit 5 alpha-dihydrotestosterone (5-alpha-DHT) and testosterone receptors activity by blocking androgen receptors . RU 58841 and RU 56187 are eliminated from blood stream relativelly quickly, but they form a common metabolite, the N-desalkyl derivative, RU 56279 (also antiandrogen), which is eliminated much more slowly and is responsible for general adverse antiandrogenic effects. But, % of RU 58841 transformation into RU 56279 is very low (1%). Therefore, if applied topically, it has prominent local effect and untraceable general effects. Clinical studies of RU58841on topical application in Department of Pathology, University of Rochester Medical Center, revealed a potent increase in density, thickening, and length of hair in the macaque model of androgenetic alopecia.

Very powerful new receptor inhibitors. Their affinity for androgen receptors is three times higher than the affinity of testosterone. One of them, RU 58841can be used topically. It is probably on of the most promissing new drugs.

found on a site http://www.clonemyhair.com/cgi-bin/hair ... gnumber=28