Replicel Interview w/ Dr. Rolf Hoffmann & Lee Buckler | Page 2 | HairLossTalk Forums

Replicel Interview w/ Dr. Rolf Hoffmann & Lee Buckler

Discussion in '9th World Congress for Hair Research Conference' started by hellouser, Nov 24, 2015.

  1. Blackber

    Blackber Experienced Member

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    I saw that same "tv-anchor" interview. I'm not 100% sure but I believe the $3-5k number was mentioned in regards to the pricing of Replicels RCT-01 Tendon Repair Treatment. This tendon treatment uses the same/similar process as the Androgenetic Alopecia treatment so forum members were speculating that the cost would be around $3-5k for Androgenetic Alopecia as well.

    It makes sense to me that similar treatments would cost the same but as David Hall said it's really up to the clinics that offer the treatment. I tend to agree with hellouser that it will be less than a hair transplant but I'm sure there will be a premium since its a much less invasive procedure.
     
  2. hellouser

    hellouser Senior Member My Regimen

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    Update:

    Lee Buckler was just promoted as the new CEO of Replicel. David Hall is retiring.
     
  3. Blackber

    Blackber Experienced Member

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    Just did a google search and didn't see anything but I'm sure you're right.

    Lee Buckler always seems knowledgeable and well spoken in all his interviews, his knowledge of the science behind their treatments is impressive as well considering he's a business/financial guy.

    http://replicel.com/replicel-life-sciences-adds-industry-specialist-to-management-team/

    It seems like Lee was brought into Replicel with an expertise in licensing deals (Shiseido). Sounds like he also has a lot of experience working with different biotech companies.

    I think he's a good choice. Hopefully Replicel makes steady progress and we can go to Japan sometime in 2018.
     
  4. Tracksterderm

    Tracksterderm Established Member My Regimen

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  5. Tracksterderm

    Tracksterderm Established Member My Regimen

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    I know it is not the main interest here, but it will be exciting to follow Replicel and their other clinical trials, like the RCS-01. They have just injected the first patient in the clinical trial in Germany:

    http://replicel.com/replicel-announ...of-rcs-01-for-skin-aging-and-uv-damaged-skin/

    If they succeed, the company will have more financial muscle and hopefully more free time for development of the RCH-01.
     
  6. Mach

    Mach Established Member

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    https://www.google.com/patents/US20150218520?dq=inassignee:"TrichoSciences+Innovations,+Inc."&hair loss=en&sa=X&ved=0ahUKEwigueu_re7JAhVG7iYKHaBfDZEQ6AEIGzAA

    Interesting read but not sure it's exactly new. Replicel bought this company in 2010
     
  7. gchr1

    gchr1 New Member

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    since 2021/2022 is projected date, does that mean histogem is more in reach?
     
  8. Blackber

    Blackber Experienced Member

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    I suggest you listen to both interviews Hellouser posted on Replicel and Histogen. He put a lot of work into them for all of us.

    No one knows for sure and anyone that says they do is making assumptions. After I listened to the Replicel interview it sounds as if they are shooting for 2018 in Japan but most likely 2019.

    Histogen may be able to offer their product in Mexico sometime in 2017 as per Gail's interview.

    All of this is assuming they don't run into any issues....
     
  9. NewUser

    NewUser Established Member

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    I hope they don't have to finish out phase II trials, 39 months, before getting regulatory approval in Japan. I think mention of the length of phase 2, 39 months, is why some people are thinking rch-01 won't be on the market anywhere until 2020 or 2021.

    But then I read this recently about Japanese government loosening regulations for biotech and new-er cell therapies. I'm just wondering at what point during phase II might probable efficacy be demonstrated?

    Three years? Okay a little arithmetic tells me phase I safety for rch-01 lasted 12 months, so that's one year. Two more years to round out the minimum three-year time to approval in loosey goosey Japan would mean 2018 at the earliest I think.

    In Hellouser's interview with Replicel, Hoffman did say, and in a rather quiet but confident manner, that he doesn't think the cells need anything extra in response to hellouser's excellent question: Would a combo therapy of Histogen and RCH-01 produce ideal results? So their latest results were that good? It sounds to me as if they are confident that efficacy will be proven.
     
  10. Blackber

    Blackber Experienced Member

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    Good point. I'd have to listen to the interview again but when I listened to it originally I got the feeling that Hoffman alluded to it being more for maintenance and keeping what you have rather than regrowth. If it works I'm sure it'd help "damaged" follicles but I'm not sure what it's effect would be on completely miniaturized follicles. Again, it'd be nice if they released before and after pictures at some point.

    I'm not as knowledgeable as other members but as far as I know they haven't released any pictures. Can anyone confirm that?
     
  11. NewUser

    NewUser Established Member

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    I think the term maintenance is associated with older drugs for hair loss, like finasteride and minoxidil. I think we are witnessing the beginning of a new era for hair loss treatments. They will be targeting hair follicle stimulation, re-growth and even neogenesis or creating new follicles.

    From Replicel's site:

    It remains to be seen what kind of results are produced by Replicel's/Shiseido's clinical trials. As Lee Buckler said in the interview with hellouser, they will know a lot more about dosing levels, number of injections required and so on, within the next two years. iIf they can show probable efficacy, then they should have a product for licensing to dermatologists and hair clinics.
     
  12. Blackber

    Blackber Experienced Member

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    I haven't seen anything from Sheseido regarding commencement of their next clinical trial. Has anyone heard anything?
     
  13. INT

    INT Established Member

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    I applied for the clinical trial they will do in Germany. Does anyone already know when this trial will start?
     
  14. Folliman

    Folliman Established Member

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    No one knows when the trials will start, but we do know that Japan's trials are starting first. According to this, Shiseido's trials are expected to be announced in the first quarter of 2016. So, in about a month?
     
  15. Folliman

    Folliman Established Member

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    First quarter is over, no news yet :/
     
  16. distracted

    distracted Established Member

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    Their 10-K will be available sometime this month. Hopefully that will include an update although I doubt anything has changed. They are probably still waiting regulatory approval to proceed.
     
  17. Folliman

    Folliman Established Member

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    I bet the regulators are the sloths from zootopia
     
  18. GiovaniDj

    GiovaniDj New Member

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    Hope this comes out in our lifetime.
     
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  19. CopeForLife

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    Anyway youth of most of us will be wasted. Getting full head of hair at 50 after 30 years of balding subhuman life will be a minor consolation anyway.

    The only good outcome is next generation will be finally cured of this disease. Will be funny btw be the last bald generation.
     
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  20. Folliman

    Folliman Established Member

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    Half Life 3 will be out before Replicel announces phase II trials.
     

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