Randomized Trial Of Electrodynamic Microneedle Combined With Minoxid

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Pretty much what stays in the tittle, dunno if it was posted here, but here you are. Seems like Follica is REALLY onto something

Randomized trial of electrodynamic microneedle combined with 5% minoxidil topical solution for the treatment of Chinese male Androgenetic alopecia.
Bao L1, Gong L1, Guo M1, Liu T1, Shi A1, Zong H2, Xu X1, Chen H1, Gao X1, Li Y1.
Author information
1
a Department of Dermatology , The First Affiliated Hospital of China Medical University , Shenyang , China.
2
b Department of Neonatology , Shenzhen Maternity and Child Care Hospital , Shenzhen , China.
Abstract
BACKGROUND:
In treating androgenetic alopecia, 5% minoxidil is a commonly used topical drug. By using electrodynamic microneedle at the same time may increase absorption of minoxidil and further stimulate hair growth.

OBJECTIVE:
A 24-week, randomized, evaluator blinded, comparative study was performed to evaluate the efficacy of treating Chinese male androgenetic alopecia using microneedle combined with 5% minoxidil topical solution.

METHODS:
Randomized subjects received topical 5% minoxidil (group 1, n = 20), local electrodynamic microneedle treatments (group 2, n = 20), or local electrodynamic microneedle treatments plus topical 5% minoxidil (group 3, n = 20). A total of 12 microneedle treatments were performed every 2 weeks with 2ml 5% minoxidil delivery in group 3 during each microneedle treatment. Patient receiving topical 5% minoxidil applied 1 ml of the solution twice daily over the course of the study. A total of 60 Chinese male subjects with Norwood-Hamilton type III-VI androgenetic alopecia were treated.

RESULTS:
The mean improvement in total hair density from baseline to 24 weeks was 18.8/cm2 in group 1, 23.4/cm2 in group 2, and 38.3/cm2 in group 3. The hair growth in the 3 groups was significantly different (P = 0.002), but there were no significant differences in toxicity found between the 3 groups.

CONCLUSIONS:
Treatment with microneedle plus topical 5% minoxidil was associated with the best hair growth.

KEYWORDS:
Androgenetic alopecia; Chinese; microneedle; minoxidil


https://www.ncbi.nlm.nih.gov/pubmed/29028377
 
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