Procyanidin Oligomers Selectively And Intensively Promote Proliferation Of Mouse Hair Epithelial Cel

Dimitri001

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This is a study about some chemicals found in grape seeds promoting hair growth.

"We have already performed toxicologic studies (Takahashi et al. 1999) and a human pilot clinical study using procyanidin B-2, and confirmed that it is safe enough for topical use of procyanidin B-2 and effectiveness in curing androgenetic alopecia.3We are now improving the industrial process for manufacturing procyanidin oligomers, and are planning a large-scale human clinical test."

This was published in 1999. Anyone know what came of this?
 

PuzzleheadedNote3

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Theres a bunch of studies of procyanidin b2 being really.effective. the issue is that its incredibly.difficult to source the compound at the concentrations they use in the studies which is 1%. Trying to buy 100mg costs a couple 100 bucks. Also procyanidin arent the most stable and generally have low bioavailability due to digestion. Also molecular weight is a bit of an issue since its in the realm of 560ish Daltons which is important for.topical application.

Studies have shown it is effective though orally and topically just getting the stuff in a pure form is impractical
 
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