Possible treatment for Hair loss?

[lordhair]

As DHT binding to the Androgen Receptors on certain hair follices is thought to be the main cause of hair loss, could a pill treatment be invented that just binds to these receptors and doesn't lower DHT - a sort of magic bullet?

Because if there was a treatment that doesn't reduce the amount of DHT in the bloodstream there wouldn't be the possibility of side effects

Or is it the case that a certain amount of DHT/Androgen Receptor binding is necessary for normal hair growth? The background info on this site suggests that

Just a thought

 

[Zen2Bald]

The problem is that there are DHT receptors all throughout the body/brain. This is why one would need a topical DHT blocker (without systemic absorption) to leave the rest of the body unaffected.

 

[lordhair]

Might the hair follicle receptors be different to the other ones in the body though?

 

[Zen2Bald]

Might the hair follicle receptors be different to the other ones in the body though?

Yes you make a good point. I dont really know enough about it to comment though.

 

[Petchsky]

As DHT binding to the Androgen Receptors on certain hair follices is thought to be the main cause of hair loss, could a pill treatment be invented that just binds to these receptors and doesn't lower DHT - a sort of magic bullet?

Because if there was a treatment that doesn't reduce the amount of DHT in the bloodstream there wouldn't be the possibility of side effects

Or is it the case that a certain amount of DHT/Androgen Receptor binding is necessary for normal hair growth? The background info on this site suggests that

Just a thought

There called anti androgens and i used in topical form, that way you don't experience the side effects that are possible from propecia. Not as good though IMO.

 

[not me!]

As DHT binding to the Androgen Receptors on certain hair follices is thought to be the main cause of hair loss, could a pill treatment be invented that just binds to these receptors and doesn't lower DHT - a sort of magic bullet?

Because if there was a treatment that doesn't reduce the amount of DHT in the bloodstream there wouldn't be the possibility of side effects

Or is it the case that a certain amount of DHT/Androgen Receptor binding is necessary for normal hair growth? The background info on this site suggests that

Just a thought

I think youre referring to a competitive enzyme inhibitor. Another option would be a non-competitive enzyme inhibition device.

 

[lordhair]

There called anti androgens and i used in topical form, that way you don't experience the side effects that are possible from propecia. Not as good though IMO.

What I'm thinking is that a pill form inhibitor would be more effective than topicals, because there would be no problems with absorption

I think youre referring to a competitive enzyme inhibitor. Another option would be a non-competitive enzyme inhibition device.

So do you think it might be an option?

 

[gonna_win]

It's posssible but know that DHT connect's to the androgen receptors and then the immune system see's the hair folicles as a foreign body and attack it causing male pattern baldness. I am not aware of anyone that know's weather or not if any other substance connected to the androgen receptors weather or not the immune system would see the hair folicles as a foreign body and attack it.

It's a very good point out pointed out lordhair, it would be good if someone conducted an study into the matter.