PGD2 / PGE2 Supplement List To Take

thedoubter

Member
Reaction score
2
Can anyone highlight the respective supplements to reduce PGD2 and promote PGE2 whether that is topically or systemically?

I have started to take:

PGD2 Reduction:
Luteolin (Systemtically)

PGE2 Promotion:
Castor Oil Shampoo (topically)
Castor Oil to the crown overnight (topically)

What else should be in the armour
Thanks
 

Ticken

Established Member
My Regimen
Reaction score
63
Immediate release niacin to release and reduce pgd2 levels in scalp.

"It is interesting to note the opposing effects of PGD2 (the prostaglandin that induces the niacin flush) and PGE2 in the balding model (above), where chronically high PGD2 resulted in suppression of PGE2. A pulsatile release of PGD2 (an ACUTE release) as in the niacin flush would be anti-inflammatory, not pro-inflammatory as with chronically high PGD2. Hence, you could see an INCREASE in PGE2 by suppressing chronically high PGD2. The balding model, in fact, shows hair growth and the cessation of hair follicle death resulting from slight modulation in the ratio of PGD2/PGE2, in which PGE2 is increased, while chronically high PGD2 levels are reduced to “normalize” the ratio. The niacin flush causes pulsatile, not chronic, release of PGD2."

 

Isneezedsohard

Experienced Member
My Regimen
Reaction score
320
Immediate release niacin to release and reduce pgd2 levels in scalp.

"It is interesting to note the opposing effects of PGD2 (the prostaglandin that induces the niacin flush) and PGE2 in the balding model (above), where chronically high PGD2 resulted in suppression of PGE2. A pulsatile release of PGD2 (an ACUTE release) as in the niacin flush would be anti-inflammatory, not pro-inflammatory as with chronically high PGD2. Hence, you could see an INCREASE in PGE2 by suppressing chronically high PGD2. The balding model, in fact, shows hair growth and the cessation of hair follicle death resulting from slight modulation in the ratio of PGD2/PGE2, in which PGE2 is increased, while chronically high PGD2 levels are reduced to “normalize” the ratio. The niacin flush causes pulsatile, not chronic, release of PGD2."

Love me a niacin flush bbbbbbbbyyyyyy
 

xaragedom

Established Member
My Regimen
Reaction score
65
for increasing PGE2 you can simply put PGE2, for decreasing PGD2 you can type COX-2 inhibitors (they might decrease PGE2 as well although PGD2 is decreased in much greater amount) and some anti-histamines also could decrease PGD2.
 
Top