Oral spironolactone, Oral Minoxidil and Dutasteride

DontWant2BeBald

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Same! He's seen awesome success for losing so much. From what I could figure out he went like 6+months off spironolactone before he had stopped updating and hadn't lost any hair at all. Also a side note, I did try RU before for however long 10 grams lasted (6 months maybe) and didn't see any help...

Bagels: That's what I had originally thought/hoped...But I took prohormones for 3 months and that's when my hairloss started. That was more than 3 years ago...sadly I lost a lot of ground since then since I got lazy taking dutasteride because I had recovered so well over the course of the last few years...Now I know my hair is susceptible to my natural DHT...:(

I too tried Ru and saw no improvemnts, sad thing is dutasteride and finasteride are not enough to stop my hairloss alone and im only 18, man i really dont wanna be bald by 20

Where did you get your spironolactone from? Also have you noticed no gyno at all? I was thinking maybe I could make a topical solution of spironolactone at a hight percentage and see where it takes me befroe trying it orally, I know im a little succeptable to gyno
 

audoyle

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Update: About 3 1/4 months into regimen of 200mg spironolactone/10mg oral minoxidil and dutasteride. From my previous update which was 2.5 months, not much has change. It seems as if almost all my hairs have returned on my hairline but many are very thin but getting longer vellus hairs. Initially It had looked very promising as these hairs popped up in areas of which had been bald for multiple years but they are taking quite some time to thicken up. I am still hopeful in returning to my youth hairline or very close. Pics are below and can be compared to my 3 month that are posted in my fire post.

Also I had just applied minoxidil hence my temples seem thing/shiny. In reality they don't look thin at all really. Especially to someone who isn't balding.

Overview of head: http://imgur.com/pCgBOcH
Right temple (side with most vellus/ministrized hairs): http://imgur.com/a/kZAGN
Left Side( very close to full recovery)http://imgur.com/HGbamA0

DontWant2BeBald: I get all my meds from alldaychemist. No gyno thus far. Lower libido is all as of now (Fingers crossed)
 

DontWant2BeBald

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great stuff, keep us updated man. Im probably gonna give spironolactone a go myself in the next year if I cant find a topical solution
 

abovedagame

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Your results look great. I hope they continue. However in my roughly 10 years on these boards I don't think I've seen someone able to continue using oral spironolactone long term unless they were trans or cis because of side effects. Hope your an exception.
 

audoyle

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Thank you for the kind words abovedagame and dontwant2bebald. I will continue updating and I do hope to continue. abovedagame, I encourage you to check out a thread I linked in my inro that shows a young male who ran the same regimen for over three years without side effects. Ultimately i would like to regain most of my hair and hopefully maintain on 100mg along with dutasteride. We'll see tho!

Also slight update. For some reason I had a small pea sized lump under one of my nipples for quite a few years that has seemed to almost disappear. Not quite sure the cause of this but generally that would be lower to no estrogen...Will update with pics in the at the 4 month mark (Dec 24)
 

audoyle

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So just an update. It's been about 4 1/2 months and so far the only sides are lower libido. I have not uploaded new pictures as I broke my phone and the camera is not working at the moment. Expect pictures in a few weeks. Progress from my previous pictures has been minimal and my only sides are still a slightly lower libido. Progress has been slow the past few months and I actually think this may be caused by low estrogen in my body. Reasons for me believing this are, I have lost zero muscle and actually lean-bulked up to 200 lbs over break and added a few lbs of muscle as well as a ton of strength. My libido has been increasing as of lately and have had the urge to masturbate along morning wood. I am hopefully going to get some bloodwork done to see if my estrogen is low or possibly spironolactone is not decreasing my testosterone much. Nonetheless, I am happy with the progress I've made in four months and don't have to constantly worry about my hair throughout the day.

Feel free to ask any Q's.
 

DontWant2BeBald

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So just an update. It's been about 4 1/2 months and so far the only sides are lower libido. I have not uploaded new pictures as I broke my phone and the camera is not working at the moment. Expect pictures in a few weeks. Progress from my previous pictures has been minimal and my only sides are still a slightly lower libido. Progress has been slow the past few months and I actually think this may be caused by low estrogen in my body. Reasons for me believing this are, I have lost zero muscle and actually lean-bulked up to 200 lbs over break and added a few lbs of muscle as well as a ton of strength. My libido has been increasing as of lately and have had the urge to masturbate along morning wood. I am hopefully going to get some bloodwork done to see if my estrogen is low or possibly spironolactone is not decreasing my testosterone much. Nonetheless, I am happy with the progress I've made in four months and don't have to constantly worry about my hair throughout the day.

Feel free to ask any Q's.

YO u must be getting fake spironolactone, I dont think there is any way that you wont lose muscle let alone build muscle on spironolactone. Ive been trying to buld Im 165 atm and I have very high test and its still a struggle. Anyway keep us updated, very interested to see how this goes
 

audoyle

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I really do highly doubt that it is fake. It's from alldaychemist, smells minty and taste like ****; but yes this is a bit odd to say the least. It's also worth noting that I've been a lean 200 lbs before and regaining lost muscle is always much easier then building new. Also their are some credible studies out there that have conflicting data on whether it actually lowers testosterone or not. The only people on hairloss boards who generally take spironolactone also take it alongside estrogen which definitely lowers testosterone. Not sure what to make of all this.
 

DontWant2BeBald

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I really do highly doubt that it is fake. It's from alldaychemist, smells minty and taste like ****; but yes this is a bit odd to say the least. It's also worth noting that I've been a lean 200 lbs before and regaining lost muscle is always much easier then building new. Also their are some credible studies out there that have conflicting data on whether it actually lowers testosterone or not. The only people on hairloss boards who generally take spironolactone also take it alongside estrogen which definitely lowers testosterone. Not sure what to make of all this.

Blocks the receptor so it doesnt matter if it lowers it or not. Yea if the taste is that spironolactone minty/sweat taste than its probably real. What dose were you using? Someties when people play with their hormones their libido increases. When I first used dutasteride my libido was way higher than it is now
 

audoyle

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Exactly. That's why I'm thinking as well. My testosterone may be relatively high still but just being blocked at the receptor level. Still on 200 mg along with .05 dutasteride everyday. Muscle growth isn't all testosterone either. Estrogen plays a large role along with insulin and nitrogen levels in the muscle. I mean I know of women who are lean and big and are natural and obviously have very little testosterone in comparison to a male of the same size.
 

audoyle

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http://www.medpagetoday.com/MeetingCoverage/ENDO/46497

Super super interested study/article done on spironolactone and estrogen. Basically in this study spironolactone did not lower testosterone levels at all, actually increase them, and that estrogen alone doesn't lower testosterone enough for all MTF so the two are combined. Even some of the participants did not see a big enough decrease for MTF levels with spironolactone and estrogen combined.

Also worth noting everyone reacts differently to drugs, this is also quite clear from the study as some patients had to be on 8 mg estradiol along with sprio everyday so have MTF levels of male hormones. Coming up on 5 months and my libio is only slighlty lowered while I've gained muscle and strength and have noticed no sides.
 

DontWant2BeBald

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thats because of fsh and lh. Since youre receptros are blocked your body continues to make testosterone due to the lack of the negative feedback loop that happens. Doesnt matter tho since no matter how much test u have if your receptors are blocked it would make little difference
 
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I went on AllDayChemist and it says you need to have a prescription to get stuff from there. How did you get oral spironolactone, because I assume a doctor wouldn't give you a prescription for spironolactone just for hair loss.
 

audoyle

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thats because of fsh and lh. Since youre receptros are blocked your body continues to make testosterone due to the lack of the negative feedback loop that happens. Doesnt matter tho since no matter how much test u have if your receptors are blocked it would make little difference

While I do agree, I feel as if my receptors are nowhere near completely blocked. The article also stated that the Dr. had no idea why testosterone levels were raised and it goes against what the medical community knows about the drug.

And as far as a prescription goes, they do not ask for it. Just click the box that you will send it in or w.e. Are you planning on taking spironolactone? If you are may I ask what's your age?
 

audoyle

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Update: So it's been 7 1/2 months since starting on 200mg of oral sprio but only on 5mg of oral minoxidil a day (beard was growing to fast and was a pain). Side effects are still non existent besides lower libido (still easily can get and maintain erections), and overall less aggressiveness in the gym. I've still honestly kept most my muscle and am a decent 200 lbs at the moment with a ****ty low calorie diet due to university. Currently my camera is broken on my phone so I do not have any pictures for update. Progress is still being made from the last update however still slow. After loosing a ton of hair after slacking on my previous regimine (dutasteride,finasteride,spironolactone) I got back to what I had lost extremely quick with spironolactone but new hairs around the hair line are still coming of which I had never previously seen since losing them (from spironolactone). though not much of color but getting increasing longer/thicker.

Will hopefully get some pictures up within the next month or so. Leave any questions here.
 

jgray201

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Glad you are getting results. My story was the one you alluded to in your original post. Just watch out for Gyno, it took quite a while to kick in for me probably over a year but sounds like you are prepared. If you do get gyno i would recommend Raloxifene over Tamox, from my experience less likely to negatively affect hair. Someone earlier mentioned that you can't maintain switching to different products such as RU. I both agree and disagree. I think minoxidil is a very specialist product and if you were to stop oral minoxidil some hairs would be lost unless you replaced with something similar i.e topical minoxidil. But i did not lose much if any ground switching from Oral spironolactone to topical RU after a few years because they have similar modes of action.
 

audoyle

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Yes of course I know you! How is your hair doing? Still just maintaining on RU and minoxidil? I do have tamox on hand but will definitely look into the other serm!
 

jgray201

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Yes, still maintaining. I think I go through a fair few sheds so there are times where my hair dips but then always improves. I'm using dutasteride, RU and Oral minoxidil. But i've also been using OC and castor oil for about 6 months. This has seemed to improve overall appearance of hairs, reduce the shedding periods and thickened the more wispy hairs, especially at the hairline. It's also darkened my hair quite considerably. Best of luck!
 
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