Yes I think it's because it decrease my GFR. I tried it 2 time and each time it give me prostatis symptoms ... with very hurting burning sensation on penis urethra and balder a d these symptoms can be caused by renal problems....
After stopping it my gfr came back to normal
Topical is OK for me certainly because there is no the peek like on oral:
I think minoxidil has about played out its usefulness. I bought a kilo of it.. If you take too much orally you will get rapid heartbeat..I still use it in various ways.. but truthfully never did a thing to report..
For anyone weighing oral minoxidil, a summary of what is known so far (I work on the editorial team of an online pharmacy, general information only):
Results: studies and large clinic series in men using roughly 1.25-5 mg a day report improvement in a majority after 6-12 months, broadly similar to or slightly better than 5% topical, with better adherence because it is one tablet a day.
Common side effects: extra body and facial hair (most frequent), ankle or hand swelling, faster heart rate or palpitations, light-headedness. These are dose-related and often settle with a lower dose.
Before starting: check blood pressure and resting heart rate; people with heart disease or on blood pressure medicines need extra caution.
Prostatitis is not a recognised side effect of minoxidil, so if pelvic symptoms appear, get them checked separately.
Best results come with a DHT blocker alongside, since minoxidil does not stop the underlying process.