BlahBlah12
Established Member
- Reaction score
- 8
Just one of many studies which show opioids lower testosterone and androgens.
Important quotes:
The effects of opiates, especially morphine, on
male rodent gonadal function and sex hormones
have been well documented. Marked decreases in
seminal vesicle and prostate weights, and significant
reductions in serum testosterone levels, have
been reported (Tokunaga et al, 1977; Bruni et al,
1977; Muraki et al, 1978; Meites et al, 1979).
Plasma androgen levels studied following the injection
of the opioid agonists morphine sulfate (0.5-1.0 m?/
kg), 13-endorphin (10-20 mg/kg), and ID-Ala2, D-Leu 1-
enkephalin (DADLE; 5-20 ?igfkg), and the opioid receptor
antagonist naloxone (0.5-2.0 mgfkg) in nonrestrained
adult male rhesus monkeys. Drugs were administered
and blood samples were collected through
indwelling jugular catheters. Morphine (1.0 mg/kg) and
DADLE (10.0 pg/kg) decreased androgen levels by 70%
and 34%, respectively. Significant decreases occurred
80 minutes after drug injections, and levels remained
depressed for 180 minutes;
http://www.andrologyjournal.org/cgi/reprint/5/5/339.pdf
ive always wondered why my hair thickened greatly along with my hairline when i was in the hospital for 2 months following an accident. Could it be the fact that i was on painkillers 3 times a day including morphine for the hospital duration had a positive effect on my hair?
Important quotes:
The effects of opiates, especially morphine, on
male rodent gonadal function and sex hormones
have been well documented. Marked decreases in
seminal vesicle and prostate weights, and significant
reductions in serum testosterone levels, have
been reported (Tokunaga et al, 1977; Bruni et al,
1977; Muraki et al, 1978; Meites et al, 1979).
Plasma androgen levels studied following the injection
of the opioid agonists morphine sulfate (0.5-1.0 m?/
kg), 13-endorphin (10-20 mg/kg), and ID-Ala2, D-Leu 1-
enkephalin (DADLE; 5-20 ?igfkg), and the opioid receptor
antagonist naloxone (0.5-2.0 mgfkg) in nonrestrained
adult male rhesus monkeys. Drugs were administered
and blood samples were collected through
indwelling jugular catheters. Morphine (1.0 mg/kg) and
DADLE (10.0 pg/kg) decreased androgen levels by 70%
and 34%, respectively. Significant decreases occurred
80 minutes after drug injections, and levels remained
depressed for 180 minutes;
http://www.andrologyjournal.org/cgi/reprint/5/5/339.pdf
ive always wondered why my hair thickened greatly along with my hairline when i was in the hospital for 2 months following an accident. Could it be the fact that i was on painkillers 3 times a day including morphine for the hospital duration had a positive effect on my hair?