Havent seen these. Sorry if their old. Scroll through it and youll see the pics.
http://pdfaiw.uspto.gov/.aiw?PageNum=0&docid=20170042859
Nice find, but why their pics are always so shady...
RiverTown is a mystery, i would like to know more about their third main ingredient RT175, because the two others, Minoxidil and C
yclosporin A are known for quite some time now, and we all know their efficiencies are...mixed
Here is their patent from 2017
http://www.freepatentsonline.com/y2017/0042859.html
"RT175 binds with high affinity to FK506 binding protein 4 (“FKBP52”). FKBP52 is known to act as a molecular chaperone for the glucocorticoid receptor (“GR”). After binding to ligand, the RT175/GR complex translocates to the nucleus. Banerjee A., et al. Control of glucocorticoid and progesterone receptor subcellular localization by the ligand-binding domain is mediated by distinct interactions with tetratricopeptide repeat proteins,
Biochemistry, 2008, 47, 10471-10480. It has been shown that that RT175 treatment of fibroblasts for 2 hours results in the translocation of FKBP52 to the nucleus, presumably with its cargo. This timeframe is consistent with cDNA array studies that have shown a significant upregulation of chromatin remodeling via the transcription factors Ikaros and Afq1, suggesting that treatment with RT175 results in alteration in chromatin structure as the cells are reprogrammed, including the up-regulation of secreted molecules that are associated with hair growth, wnt1 and IGF2."
Way too complex for me, i just noticed wnt1 and IGF2 signaling
