good find!
in the study they say they used (30% polyethylene glycol + 70% ethanol), as vehicle on mice. cilostazol (0.2 and 1%)..." any mice here?
anyway here some highlights from the study:
"cilostazol and 2% minoxidil, a hair growth inducer used as a positive control, similarly thickened the back skins of the mice."
"findings suggest that topical cilostazol enhances hair growth effectively. Further, cilostazol is suitable for topical use because it is expected to be absorbed through the skin without difficulty due to its low molecular weight (369.46 g/mol). Moreover, the long clinical history of its oral use guarantees its systemic safety following topical use, particularly because its serum level is much lower when it is applied topically [20]. Additionally, in the present
study, cilostazol-treated mice did not show any evident adverseeffects."
"In summary, our results demonstrate that cilostazol significantly stimulates hair growth both in vitro and in vivo. In addition, it accelerates in vitro proliferation of DPCs, enhances ex vivo hair shaft elongation, and induces in vivo anagen hair induction through the promotion of vessel formation."
"The results showed that at concentrations of 1–10 mM, cilostazol-treated DP-CM noticeably enhanced ORSC proliferation more than the vehicle-treated DP-CM. In addition, the most effective concentration of cilostazol-treated DP-CM was 1 mM"
mkayyyy
