need to take finasteride all day in week or 1 day break?
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Vlatch
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It depends on what you want, dutasteride has a much longer half life than finasteride so it won't matter much if you skip a dose or two, however, the results are dose dependent : in studies, 2.5mg a day gets better results than 0.5mg a day, which gets better results than 0.1mg a day.
It means you will get results even if you take one pill a week, but you will get better results if you take it every day.
You don't need to take one day break a week, but you can.
By the way you can also take a one day break with finasteride, even if it has a serum half life of only 6-8 hours, studies show that DHT levels start rising again during the third day after a 1mg intake. It's a matter of preference.
No, finasteride must be taken everyday, if you really want results.
It's common sense, that way the DHT is kept at a constant and low level.
People recommending here skipping days, taking ridiculous-low doses such as 0.125(which most probably does nothing), must be ignored.
IF Merck and FDA approved the medicine with that way of administration: 1mg a day, i prefer to believe them, not some obscure "amateur" scientist dude on the internet that says otherwise.
In my common-sens, either you take 1 mg a day, or you do not take any.
It's common sense, that way the DHT is kept at a constant and low level.
People recommending here skipping days, taking ridiculous-low doses such as 0.125(which most probably does nothing), must be ignored.
IF Merck and FDA approved the medicine with that way of administration: 1mg a day, i prefer to believe them, not some obscure "amateur" scientist dude on the internet that says otherwise.
In my common-sens, either you take 1 mg a day, or you do not take any.
Vlatch
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DHT levels after only one dose of finasteride and finasteride inhibition curve :
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I've seen these many times.
From my personal experience it is better to stick to it daily. Result: no shed and maintenance for 4 years.
Really, what's the point in skipping 1 day a week?
And it depends on male pattern baldness agressiveness, maybe for some, 1 mg EOD is fine, but for others it doesn't bring results.
Of course those of you in the early stages, or with full head of hair but balding gene present in the family, you can experiment at the start with low dose/skipping days, but someone already with NW2-3 and rapid hair-loss should just stick to the routine from the prospect:1 mg a day. Maybe even more, if hair-loss is bad/agressive.
Because that graphs don't tell the whole story, there is also the absorption issue. Not everyone's body is the same.
And even the second chart suggest a clear dependance between dose and DHT reduction.
I would like the DHT to stay as constant as possible, that's why i wouldn't like skipping days.
I take EOD just fine.
Even prostate patients (which is a more critical condition than male pattern baldness), are often prescribed 5 mg 3x/week.