Need Adice -Adding dutasteride a few Times/Week to Propecia Regiment

[mbehr22]

I take 1mg propecia/day for diffuse thinning over the top of my head.

I have some temple loss.

I have read a few posts where guys have not switch from propecia to avodart, but have created a hybrid regiment of dutasteride once or twice a week, and they take propecia on the other days ...

What are the benefits of doing this? I guess Im asking what is the effective half life of dutasteride if I take it on every Monday and Thursday, while continuing propecia on Sun, Tues, Wed, Fri, and Sat ... would the dutasteride last long enough to be effective over the 2 off days before the next dose of advodart was taken? Would this facilitate regrowth, not just the loss?

Will this increase my odds of thickening my hair? Thats my goal ... Im 30 and would like to have defect free children in a few years ... but I would also like to increase the overall thickness of my hair ...

Any advice appreciated !!


Sun -- Mon -- Tues -- Wed -- Thurs -- Fri -- Sat

 

[Pondle]

dutasteride has a long half-life - something like 5 weeks, if I remember rightly - so in theory you can skip days and still have effective DHT inhibition. However, hair loss trials with dutasteride only tested a variety of dosages taken every day.

In comparison to dutasteride, finasteride has a short half-life - 6-8 hours - so you need to take it daily for maximum benefit (although this opens up a whole other debate).

I think one reason for a dutasteride / finasteride combo is if you're taking dutasteride bought online and you aren't 100% sure if it's genuine. You lose nothing by replacing one or two days of finasteride with your new drug - if it isn't kosher, you still have effective inhibition from finasteride.

 

[mbehr22]

thanks!

whats your take on dutasteride's effect on birth defects?

how far along is GSK in the trials in regards to using dutasteride as a hairloss drug? whats the FDA say?

 

[Pondle]

Well GSK cancelled its planned phase III trials back in 2002, I think - apparently for commercial reasons. But now it's undertaking what it calls a "phase III" study with a relatively small group of subjects in Korea. So watch this space.

As far as the potential for birth defects goes, small amounts of dutasteride have been recovered from the semen in subjects receiving Avodart 0.5mg per day. Based on studies in animals, it is unlikely that a male foetus will be adversely affected if his mother is exposed to the semen of a patient being treated with dutasteride (the risk of which is greatest during the first 16 weeks of pregnancy).

However, as with all 5 alpha reductase inhibitors, when the patient's partner is or may potentially be pregnant it is recommended that the patient avoids exposure of his partner to semen by use of a condom.

 

[mbehr22]

does anyone here use a finasteride/dutasteride hybrid regiment?

 

[hair_tomorrow]

does anyone here use a finasteride/dutasteride hybrid regiment?

Beginning in March, I went to dutasteride M, W, S and 1mg finasteride the other 4 days.

 

[Pondle]

I'm going hybrid myself soon! I've got Dutas from Inhouse and I'm going to start once per week and ramp it up from there (as soon as I have the balls to swallow the damn things). Next batch will be genuine Avodart from Merlonipharma. I'll keep using Proscar as my backup.

 

[Pondle]

how do you think dutasteride in 19 years its ok?

You only started finasteride in Sept 06, give it at least a year, preferably two, before you judge the results. Then you can think about dutasteride. I imagine dutasteride is fine at 19, after all you should have reached sexual maturity by now! 8)

 

[Pondle]

i am cant wait so much time i have not so much hair

Results aren't instant with any treatment. Even the fastest responders only see the effect of finasteride after 3 or 4 months. Most perceptible differences are apparent after 12 months. Remember, hair grows slowly and hair cycles take years.

 

[mbehr22]

thanks pondle

patience is the toughest part when it comes to losing your hair

 

[mbehr22]

Any advice?

 

[mbehr22]

does anyone here use a finasteride/dutasteride hybrid regiment?

Beginning in March, I went to dutasteride M, W, S and 1mg finasteride the other 4 days.

any results? Im thinking about a Monday=.5 dutasteride, followed by 1mg the other 6 days ... good idea? pointless? is one day enough (coupled with finasteride the other days) to see results?

[/b]

 

[beaner]

Do you guys even realize that if you're taking dutasteride 2-3 times a week, then you have absolutely no need to take finasteride? 1 dutasteride capsule every 5 days is roughly the equivalent of 5mg of finasteride per day. You're just giving your liver unnecessary work to do.

 

[hair_tomorrow]

Do you guys even realize that if you're taking dutasteride 2-3 times a week, then you have absolutely no need to take finasteride? 1 dutasteride capsule every 5 days is roughly the equivalent of 5mg of finasteride per day. You're just giving your liver unnecessary work to do.

Beaner - that's what I heard too. But after taking dutasteride 2x weekly and finasteride 2x weekly - I went from a NW5a whose rear bald spot had previously filled in - back to a 5a w/ balspot after approx 2 - 3 months.

So in my instance - the dutasteride 2x weekly wasn't nearly enough.

 

[hair_tomorrow]

does anyone here use a finasteride/dutasteride hybrid regiment?

Beginning in March, I went to dutasteride M, W, S and 1mg finasteride the other 4 days.

any results? Im thinking about a Monday=.5 dutasteride, followed by 1mg the other 6 days ... good idea? pointless? is one day enough (coupled with finasteride the other days) to see results?

[/b]

Results? Hair's looking good. Mucho vellousnous. But no serious regrowth to report after 2.5 months (still too soon to tell though).

As far as your regimen - it's difficult for me to advise you. I'm strictly trial and error myself and trying to make up lost ground.

 

[Pondle]

does anyone here use a finasteride/dutasteride hybrid regiment?

Beginning in March, I went to dutasteride M, W, S and 1mg finasteride the other 4 days.

any results? Im thinking about a Monday=.5 dutasteride, followed by 1mg the other 6 days ... good idea? pointless? is one day enough (coupled with finasteride the other days) to see results?

[/b]

The only reason for a hybrid dutasteride/finasteride regimen is if you suspect one of your drugs may be counterfeit, old or otherwise low quality. I am taking both because I am not 100% sure about my Dutas, and because I wanted a phased transfer. dutasteride will generally replace finasteride completely, because it is a much more potent DHT-inhibitor and has a longer half life. The two drugs will not work together synergistically.

 

[beaner]

Do you guys even realize that if you're taking dutasteride 2-3 times a week, then you have absolutely no need to take finasteride? 1 dutasteride capsule every 5 days is roughly the equivalent of 5mg of finasteride per day. You're just giving your liver unnecessary work to do.

Beaner - that's what I heard too. But after taking dutasteride 2x weekly and finasteride 2x weekly - I went from a NW5a whose rear bald spot had previously filled in - back to a 5a w/ balspot after approx 2 - 3 months.

So in my instance - the dutasteride 2x weekly wasn't nearly enough.

Good to know if I ever decide to make the switch. Thanks

 

[Stu85]

Just thought I'd drop in and say that I'm also considering a hybrid of finasteride and dutas. I'd rather just use the Dutas, but, like others here, I can't be sure of the quality of what I'm getting, so it's gonna have to be a combo of both :/

 

[hair today gone tomorrow]

Just thought I'd drop in and say that I'm also considering a hybrid of finasteride and dutas. I'd rather just use the Dutas, but, like others here, I can't be sure of the quality of what I'm getting, so it's gonna have to be a combo of both :/

Well then your gonna have to go to your Doctor to get he finas...otherwise whats the point?

 

[Stu85]

Just thought I'd drop in and say that I'm also considering a hybrid of finasteride and dutas. I'd rather just use the Dutas, but, like others here, I can't be sure of the quality of what I'm getting, so it's gonna have to be a combo of both :/

Well then your gonna have to go to your Doctor to get he finas...otherwise whats the point?

Where did I say that I didn't already get me finasteride from my doctor?

Maybe it wan't clear, but I have been getting Proscar from my doctor. He also said he would be willing to prescribe me Avodart - but there's no way I can afford that stuff. I didn't ask if he could prescribe generic dutasteride, it must have slipped my mind. But I've never actually heard of anyone getting generic dutasteride from their doctor. Is generic Dutasteride available in British pharmacies, does anybody know?