Ok this is my experience,
Been on minoxidil 2x per day for 6 years. Regrettably I have had one or two weeks each year when I have had to switch to 1x per day. Eg on holidays or time away it just is not practical to apply it in the mornings and then go swimming straight after. My girlfriend also gets a bit annoyed with me looking "wet head" when on holiday.
Anyway, every time I have switched to x1 per day my hair has suddenly thickened! Then soon as I'm back to x2 per day I take on a bad shed, and my hair never recovers to pre holiday level.
Over the years I have slowly lost more and more hair. Started finasteride 2 years ago.
Ok, so I have just got back from a hot holiday in Greece, I have been applying x1 for two weeks, applying x2 has become a drag for me. So far my hair looks ok. I'm at the point now if I do lose anymore I'm just gonna grade it down permanently as this hair loss treatment thing is grating on me badly.
At the moment my hair looks better than pre x2 level. I'm just gonna see what happens and apply it at night only.