michael barry
Senior Member
- Reaction score
- 12
Gents,
ICX is in phase two trials right now. There may be some info this summer, but almost assuredly at the beginning of October. They shot up 20 men with 900 injects over a large area, and 100 injects on a small area of complete baldness with cultured dermal papilla cells and some other cells extracted from the men's donor areas.
There are three other companies that I know of that are working on hair cloning. One is Aderans, one is the Japanese Phoenixbio, one is the Japanese Shishedo. There are some academic interests dipping their hand in this also. ALl have filed patents with dermal papilla cultivated hair growth arts in their respective countries. So they are not pissing in the damned wind.
ICX plans on having a phase 2 B and probably another one or two "phase 2 trials" before a large phase 3 trial with a great deal of men. They are trying to get their cultivation (think breeding) method's down, and the number of injects per centimeter down and probably trying to work out an automated process with a robot to deliver the many many injections one will need.
If 10 or 15 of these men respond well and grow pretty decent hair, you all have a right to get very excited. The trials are being conducted with the Farjo transplant clinic in England.
There are some naysayers about the procedure. I'd like to address them now. Ken Washenik opened his mouth and got people's hopes way way way up back in 2000 about HM being here by 2005. He did this before any human cells were implanted in human skin. He was basing his optomism on rodent dermal papilla cells growing well on rodent skin. Human beings are more complicated than rodents. They have found that there has to be a mixture of Dermal Papilla cells and some stem cells (derived from the epilitheal cells in this instance) for the correct signalling envrionment to be present for the DP cells to get the chemcial signals that are much like yours are in your fetal development. Its complicated stuff.
As for the "direction" question. Stromal tissue seems to correct bad direction in ensuing growth phases. After a rests and sheds in the catagen and telogen phases, the papilla gets very small and migrates northward in the dermis, when it dives down again, it can re-orient itself. The stromal tissue seems to know how to direct it upright. Even men who got screwed up transplants in the eighties have seen the direction at least, begin to match what the natrual hair would have been in a given area as cycles ensue. This isn't much of a comfort for those guys however as the results are still pluggy for many of them, and they still have a mess.
Aderans has filed for patents for cylinder-shaped bio-degradable tissue scaffolds that will ensure proper direction of growth from the first phase onwards. They have recruited for their phase one trial, but have not started it. They very well might be waiting on ICX's results to see where they are before commencing their trial and adjusting their protocol. Bosley (Aderans subsidiary) has bought the rights for first chance to buy ICX's protocol, so Aderans might be able to actually save time if they adjust their protocol based on ICX's results.
IN my opinion, the 2010 date is probably a year or two too optomistic, but let me be clear................................hair cloning will happen in the future guys. The first safety phase grew hair on five out of seven men, and grew over a hundred hairs on a couple of them in a small area. They were just looking to see if there was going to be inflammation or an immune response. They werent even trying to grow hair.................but they did. Now they are TRYING to grow hair.
Some of you (MAHAIR) are very cynical about anything concerning baldness because some surgeon hacked you up. You dont think anything can ever give you your hair back and that baldness is inevitable. First off, if you catch it in time and use finasteride and topical spironolactone...............you'll keep your hair anyway and never lose it. I have just as much hair (a little more in fact) than I did five or six years ago. Ive seen pics of men who had more hair fifteen years after beginning to use finas and minoxidil. Treatments can work if you haven't LOST the hair yet. The scientist involved in this stuff very much believe its going to end baldness. Its just like a transplant, you are simply making one hair into twenty hairs and implanting the twenty hairs in the head.
If you are already bald, just buzz it for a few years (although Id still wash my head with nizoral or revita so that I dont get fibrosis up there, and might consider a copper peptide spray like tricomin for a few years once a day to keep my scalp in good shape for HM). You dont want to try to grow new hair in shiny bald, hardened scalp. At lleast use an anti-inflammatory shampoo like Nizoral on it. When they release a product, you will hear of it. It will be all over the news. I imagine it will be about four to six years from now.
ICX is in phase two trials right now. There may be some info this summer, but almost assuredly at the beginning of October. They shot up 20 men with 900 injects over a large area, and 100 injects on a small area of complete baldness with cultured dermal papilla cells and some other cells extracted from the men's donor areas.
There are three other companies that I know of that are working on hair cloning. One is Aderans, one is the Japanese Phoenixbio, one is the Japanese Shishedo. There are some academic interests dipping their hand in this also. ALl have filed patents with dermal papilla cultivated hair growth arts in their respective countries. So they are not pissing in the damned wind.
ICX plans on having a phase 2 B and probably another one or two "phase 2 trials" before a large phase 3 trial with a great deal of men. They are trying to get their cultivation (think breeding) method's down, and the number of injects per centimeter down and probably trying to work out an automated process with a robot to deliver the many many injections one will need.
If 10 or 15 of these men respond well and grow pretty decent hair, you all have a right to get very excited. The trials are being conducted with the Farjo transplant clinic in England.
There are some naysayers about the procedure. I'd like to address them now. Ken Washenik opened his mouth and got people's hopes way way way up back in 2000 about HM being here by 2005. He did this before any human cells were implanted in human skin. He was basing his optomism on rodent dermal papilla cells growing well on rodent skin. Human beings are more complicated than rodents. They have found that there has to be a mixture of Dermal Papilla cells and some stem cells (derived from the epilitheal cells in this instance) for the correct signalling envrionment to be present for the DP cells to get the chemcial signals that are much like yours are in your fetal development. Its complicated stuff.
As for the "direction" question. Stromal tissue seems to correct bad direction in ensuing growth phases. After a rests and sheds in the catagen and telogen phases, the papilla gets very small and migrates northward in the dermis, when it dives down again, it can re-orient itself. The stromal tissue seems to know how to direct it upright. Even men who got screwed up transplants in the eighties have seen the direction at least, begin to match what the natrual hair would have been in a given area as cycles ensue. This isn't much of a comfort for those guys however as the results are still pluggy for many of them, and they still have a mess.
Aderans has filed for patents for cylinder-shaped bio-degradable tissue scaffolds that will ensure proper direction of growth from the first phase onwards. They have recruited for their phase one trial, but have not started it. They very well might be waiting on ICX's results to see where they are before commencing their trial and adjusting their protocol. Bosley (Aderans subsidiary) has bought the rights for first chance to buy ICX's protocol, so Aderans might be able to actually save time if they adjust their protocol based on ICX's results.
IN my opinion, the 2010 date is probably a year or two too optomistic, but let me be clear................................hair cloning will happen in the future guys. The first safety phase grew hair on five out of seven men, and grew over a hundred hairs on a couple of them in a small area. They were just looking to see if there was going to be inflammation or an immune response. They werent even trying to grow hair.................but they did. Now they are TRYING to grow hair.
Some of you (MAHAIR) are very cynical about anything concerning baldness because some surgeon hacked you up. You dont think anything can ever give you your hair back and that baldness is inevitable. First off, if you catch it in time and use finasteride and topical spironolactone...............you'll keep your hair anyway and never lose it. I have just as much hair (a little more in fact) than I did five or six years ago. Ive seen pics of men who had more hair fifteen years after beginning to use finas and minoxidil. Treatments can work if you haven't LOST the hair yet. The scientist involved in this stuff very much believe its going to end baldness. Its just like a transplant, you are simply making one hair into twenty hairs and implanting the twenty hairs in the head.
If you are already bald, just buzz it for a few years (although Id still wash my head with nizoral or revita so that I dont get fibrosis up there, and might consider a copper peptide spray like tricomin for a few years once a day to keep my scalp in good shape for HM). You dont want to try to grow new hair in shiny bald, hardened scalp. At lleast use an anti-inflammatory shampoo like Nizoral on it. When they release a product, you will hear of it. It will be all over the news. I imagine it will be about four to six years from now.
