HairChase said:
Its logic. Day 1 hormone levels won't resemble Day 5 hormone levels and this constant shift might be actually negative effect
You're right. Day 5 will have a lower DHT because it's had time to reduce.
Here's how the quantity of drug in the blood stream works...
Lets assume you take 0.5mg every 5 days and the half life is also 5 days. This means after 5 days you will have lost 0.25mg from the blood stream leaving 0.25mg. You then take a further 0.5 mg (0.75mg now in blood stream). At day 10 this has halved to 0.375mg. You then take a futher 0.5mg and your blood contains 0.875mg and so on.
Here's some figures (day, mg in blood just before taking drug, mg soon after taking drug)
0,0,0.5; 5,0.25,0.75; 10,0.375,0.875 ; 15,0.4375,0.9375; 20,0.46875,0.96875; 25,0.484375,0.984375; 30,0.4921875,0.9921875
It takes between 5 - 6 times the half life to achieve 99% of so called 'steady-state'
Steady-state for this regime is, approximately 13% loss of drug per day.
Day 0 (just after taking) 1mg
Day 1 0.87
Day 2 0.75
Day 3 0.66
Day 4 0.57
Day 5 0.5
Day 5 (just after taking) 1mg and the cycle repeats.
Although the level of drug in the blood follows a 'saw tooth' profile, the body reaction to the drug (in terms of DHT in the body) is much slower. The net result being the bio/chemistry plant of the body produces a relatively stable reduced level of DHT. Bryan may be able to point you towards some DHT reaction graphs. Here's one bryan posted earlier.
http://www.geocities.com/bryan50001/dutasteride ... ow-res.htm Look how slowly the DHT level responds to large single doses of drug intake. The above drug regime will hardly creates a ripple in the DHT.