Lets renew our Hopes

sadhairloss

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Hair-Raising Technology, Literally.
Karen Barrow




If your hair up north is heading south, you may have considered seeing a doctor to help you cover your shiny scalp or have even taken matters into your own hands. But the medications don't always work, and toupees can look fake, so what's a guy with a receding hair line to do?

A company in Britain claims to have found the answer: hair cloning. With a procedure that reproduces new hair from the healthy follicles on your head, Interytex claims to have successfully implanted cloned hair cells into five of seven patients, giving these lucky guys a full head of hair. There are, as of yet, no published results, but the company says that it is now moving on to further trials on men with male pattern baldness and even hopes to try it on women facing bare scalps from alopecia.

While it may be years before this procedure is available to the public, hair cloning is raising hope for many men—and women—with ever-receding hairlines.

"[Hair cloning] could be used in any patient, but it'll be most used in someone who doesn't have enough of his or her own hair for transplantation," says Dr. Walter Unger, clinical professor of dermatology at Mt. Sinai Hospital in New York.

The chance to fill an almost limitless amount of scalp is what makes hair cloning so promising.

Sprouting New Locks
Today, many men turn to hair implants to cover their bald spots. And implants can look like the real thing. But as doctors remove hair follicles from where the hair is growing and implant them in spots where the hair is bare, implants in a too large bald spot make the whole head of hair look strangely sparse. That, and the length of the procedure—spanning about 16 hours in two sessions—is the reason that only two percent of men with male pattern baldness are estimated to seek out the surgery.

But the science behind hair cloning simplifies the surgery necessary for transplantation.

In the case of hereditary hair loss, as a man ages, some of his hair follicles become sensitive to the hormone dihydrotesterone (DHT), a chemical that is also partially responsible for the formation of male characteristics.

These hair follicles shrivel up and stop growing new hair. But what's not yet understood by scientists is why follicles in the back of the head never become sensitive to DHT, as hair continues growing there throughout a man's life.

To take advantage of the faithful follicles, a surgeon trained in hair cloning would remove a few hairs from the back of the head. But instead of inserting these hairs back into the top of the scalp, as in the case of transplantation, he would take them to a lab where the hairs can be broken down into individual cells and reproduced an almost infinite number of times. Those new hair cells can then be sent back to the doctor a few weeks later, where they are reinserted into the patient's scalp. In theory, the new follicles would begin to grow hair within three months.

Hair cloning would eliminate the cutting, suturing and scarring of a transplantation procedure, says Unger, and would allow for an almost limitless amount of scalp to be covered with hair.

But Unger abandoned his research on hair cloning after the results proved less-than-successful. He was only able to successfully transplant cloned follicles in four of 23 patients in two trials, and the hair only grew well in one patient.

"We can grow a millions of cells from one hair in a matter of weeks, says Unger. "We just haven't been able to get them to successfully grow in a human head."

Time will tell if experiments by Interytex prove successful, but Unger is confident that the science is there to make hair cloning a reality.

"It will be done, it's just a question of when," he says.
 

sadhairloss

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Your skin can help to grow new hair

Asian News International

Washington,



In a major breakthrough, researchers from the Howard Hughes Medical Institute have demonstrated that stem cells isolated from the skin of mice have the power to self-renew when cultured in the laboratory, as well as to differentiate into skin and functioning hair follicles when grafted onto mice.

The researchers led by Elaine Fuchs and colleagues at The Rockefeller University isolated stem cells from a structure called the bulge, located within each hair follicle by fusing antibodies to characteristic cell surface molecules.

The scientists' analyses of the biochemical characteristics of the isolated mouse stem cells revealed that the bulge contained two distinct populations of stem cells. While the "basal" cells, are active during early development but` the "suprabasal" cells appear only after the first hair generation cycle.

Both types of cells, even after being cultured, produced hair follicles when grafted onto the skin of a strain of hairless mice.

"Previously, researchers have done similar transplant experiments with dissected parts of the hair follicle. And, while they've had evidence that hair follicle structures were forming, they didn't see generation of hair. In contrast, in our experiments, we saw quite a density of hairs, in some cases at a density that's very similar to that of normal mouse fur," Fuchs said.

She added that the stem cells they isolated showed a molecular signature of gene activity that demonstrates their "stemness" that represents the beginning of a broader effort to compare the genes activated in many stem cell types, to understand the factors that control their proliferation and differentiation.

"The information that we have now on the 'stemness' genes is allowing us to narrow in on some of the similarities among stem cells of the body," she added.
 

Dinzy

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THis is not new at all. Though these items may prove fruitful in the future they are not available now when we are all losing our hair. Plus HM is going to cost a lot of money. It looks like I will never drive a nice car if I want to have that done.

I think it is better to deal with the present and accept your hairloss if treatments dont work. You are only wasting your hope if you hang it on something that is a decade off.
 
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