- Reaction score
- 338
From the Prostaglandin protocol:
"You probably know that Androgens, especially DHT are the “main culprit” for hairloss. Well, it’s just the tip of the iceberg. People who are genetically prone to hairloss trigger an inflammatory reaction chain when Androgens dock to their scalp receptors. If left untreated the skin will express more and more PGD2 which leads to the actual hairloss. Even worse, not only will you lose your hair but the skin itself starts to genetically change and overproduce PTGDS. This means if a zone such as your temples for example have been slick bald for a while even anti androgens won’t be enough to regrow hair in that area.
So we have to take care of that nasty PGD2 production. In the past people tried COX1/COX2 inhibitors because that basically removes it right? Well, it didn’t work out. People actually lost more hair because when you snip the chain that high you also remove the beneficial PGE2 prostaglandin chain. COX inhibitors should thus be avoided."
Furthermore this is a thing.
Has anyone tried snipping Arachidonic acid chain with COX1/COX2 inhibitors and just adding in PGE2 in topical form?
May also need to replace PGI1 as well.
If you could get the right dosages then you may be able to emulate taking Topical Seti + topical PGE2
(I am not planning on testing this myself because I am looking into another route: Selenium disulphide as a PGD2 Synthase inhibitor.)
"You probably know that Androgens, especially DHT are the “main culprit” for hairloss. Well, it’s just the tip of the iceberg. People who are genetically prone to hairloss trigger an inflammatory reaction chain when Androgens dock to their scalp receptors. If left untreated the skin will express more and more PGD2 which leads to the actual hairloss. Even worse, not only will you lose your hair but the skin itself starts to genetically change and overproduce PTGDS. This means if a zone such as your temples for example have been slick bald for a while even anti androgens won’t be enough to regrow hair in that area.
So we have to take care of that nasty PGD2 production. In the past people tried COX1/COX2 inhibitors because that basically removes it right? Well, it didn’t work out. People actually lost more hair because when you snip the chain that high you also remove the beneficial PGE2 prostaglandin chain. COX inhibitors should thus be avoided."
Furthermore this is a thing.
Has anyone tried snipping Arachidonic acid chain with COX1/COX2 inhibitors and just adding in PGE2 in topical form?
May also need to replace PGI1 as well.
If you could get the right dosages then you may be able to emulate taking Topical Seti + topical PGE2
(I am not planning on testing this myself because I am looking into another route: Selenium disulphide as a PGD2 Synthase inhibitor.)
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