Is this real or just another fake news? CRISPR/Cas9 Therapy For Androgenic Alopecia: Moogene Medi

T

trialAcc

Senior Member
My Regimen
Reaction score
1,531
SaveTheMane said:
Moogene Medi of South Korea is the first company to formally introduce a CRISPR-based gene editing hair loss therapy to the world. Saw this on tressless
https://www.folliclethought.com/crispr-cas9-therapy-for-androgenic-alopecia-moogene-medi/
Click to expand...
If the info on FT isn't enough, why don't you google them? They're a real company with real science, so yes it's real in that sense. What's "fake news" is that it's anywhere close to being a reality for general use.

They say they are 2 years from human trials (or one if you go back to time of that interview), yet they have yet to present any further pre-clinical data or updates on the status of the program. I would say put it in the back of your mind and check on it in a year or so, maybe they will have a completed pre-clinical program.
 
R

Roeysdomi

Experienced Member
My Regimen
Reaction score
340
This is just finasteride without sides nothing new in terms of improvment .

sides are not the problem of treatments today . Its their the low effect of them .
 
SaveTheMane

SaveTheMane

Established Member
My Regimen
Reaction score
24
Roeysdomi said:
This is just finasteride without sides nothing new in terms of improvment .

sides are not the problem of treatments today . Its their the low effect of them .
Click to expand...
Even a cure with no sides still makes a huge difference, maybe you respond well to finasteride, but what about those with aggressive nw5+ balding genetics that need to take dutasteride? And those that don't even respond good to finasteride? A side free cure will definitely be their savior,
 
SaveTheMane

SaveTheMane

Established Member
My Regimen
Reaction score
24
trialAcc said:
If the info on FT isn't enough, why don't you google them? They're a real company with real science, so yes it's real in that sense. What's "fake news" is that it's anywhere close to being a reality for general use.

They say they are 2 years from human trials (or one if you go back to time of that interview), yet they have yet to present any further pre-clinical data or updates on the status of the program. I would say put it in the back of your mind and check on it in a year or so, maybe they will have a completed pre-clinical program.
Click to expand...
So the company is real, but again they are saying to start human trials in 2 years, which sounds very familiar as what Tsuji and every hairloss cure companies telling people since decades ago.
 
T

trialAcc

Senior Member
My Regimen
Reaction score
1,531
Roeysdomi said:
This is just finasteride without sides nothing new in terms of improvment .

sides are not the problem of treatments today . Its their the low effect of them .
Click to expand...
What? They're literally turning off the AR receptor in the follicle, as in, no possible way of male pattern baldness.
 
T

trialAcc

Senior Member
My Regimen
Reaction score
1,531
SaveTheMane said:
So the company is real, but again they are saying to start human trials in 2 years, which sounds very familiar as what Tsuji and every hairloss cure companies telling people since decades ago.
Click to expand...
What do you expect? These are all pre-clinical programs.
 
T

trialAcc

Senior Member
My Regimen
Reaction score
1,531
SaveTheMane said:
That's why he said it is basically finasteride without side effects
Click to expand...
No, it would have nothing to do with inhibiting DHT and would make follicles completely immune to androgens. Nothing like finasteride and infinitely more effective.
 
SaveTheMane

SaveTheMane

Established Member
My Regimen
Reaction score
24
trialAcc said:
No, it would have nothing to do with inhibiting DHT and would make follicles completely immune to androgens. Nothing like finasteride and infinitely more effective.
Click to expand...
As you said it is TEMPORARY so it is not a permanent treatment, you have to come back to get another treatment in time to prevent the AR from turning back on, therefore it is no different from taking finasteride everyday for your life except it can 100% stop male pattern baldness for a period of time and doesn't inhibit DHT to cause side effects.
 
T

trialAcc

Senior Member
My Regimen
Reaction score
1,531
yadonkey said:
Thats wrong

You've described something targeting the AR (androgen receptor).. this isn't targeting the AR.

It's targeting SRD5A2, which will most defo inhibit DHT production as your're targetting the gene that encodes for the enzyme that creates DHT.
Click to expand...
That's what I get for not re-reading the info, fair enough.
 
T

trialAcc

Senior Member
My Regimen
Reaction score
1,531
SaveTheMane said:
As you said it is TEMPORARY so it is not a permanent treatment, you have to come back to get another treatment in time to prevent the AR from turning back on, therefore it is no different from taking finasteride everyday for your life except it can 100% stop male pattern baldness for a period of time and doesn't inhibit DHT to cause side effects.
Click to expand...
Probably* temporary but also a "perfect fix" if there was one. Finasteride is not a perfect fix for anyone and we're tasked with taking a systematic drug for a localized problem. This is a targeted approach, so even if it did inhibit DHT it would be in the follicles only, and by temporary we're talking about months if not years between treatments.
 
Last edited:
P

pegasus2

Senior Member
My Regimen
Reaction score
4,504
It's real and it's superior to what we have today, but this and Olix are both so faaaaaaaaaaaaar away. We better be cured before those two ever make it to market.
 
R

Roeysdomi

Experienced Member
My Regimen
Reaction score
340
trialAcc said:
Probably* temporary but also a "perfect fix" if there was one. Finasteride is not a perfect fix for anyone and we're tasked with taking a systematic drug for a localized problem. This is a targeted approach, so even if it did inhibit DHT it would be in the follicles only, and by temporary we're talking about months if not years between treatments.
Click to expand...
How is that perfect fix when so much ppl keep losing hair on finasteride and dutasteride .

dht is not the real problem of hairloss. My dad has perfect nw1 at age 60 and he has more dht then me .

its our sensetivty that kill our hair and as long no compnay fix this it will be just temp soulotion
 
You must log in or register to reply here.
Community platform by XenForo® © 2010-2023 XenForo Ltd.
Top