Is This Dupa? Cte? What's Happening!?

[WHATISTHISOMG]

Hi,
I'm 20 and just graduated college. I used to have nice full hair around 6 months ago, and then I started noticing some hairline receding, so I started using Nizoral, but that ended up making my hair super stringy so I stopped (This was ~4 months ago). My donor regions have never been thinning so I was not too concerned. However, 2 days ago, I noticed some thinning on my sides, some SEVERE thinning so I went to the doctor and he said it's because of stress. I've seen some pictures online and stress related hairloss looks different than mine. Here is a picture of my hair loss: (imgur.com/a/HIAc6XU). The other reason I'm concerned about the diagnosis is that although I was pretty stressed in college, I was not really that stressed this past year, and given that Telogen Effluvium hits at most 3 months after stressful periods, I'm not sure why things have only gotten progressively worse in the past 3-4 months (When my stress levels were low). Now, does this look like DUPA or Diffuse Areata Alopecia? My Doctor prescribed finasteride but I'm too scared to use it. Any help is appreciated!

 

[DerDon]

Could be dupa. I think there's almost no chance, that Hairloss is related to sth.else than genes. I always thought it might have been Telogen Effluvium, as i was thinning on my sides as well. I even was diagnosed with it by a derm. My shedding and hairloss has never stopped and so will probably yours.
If you're lucky finasteride will help.

 

[Mapleman]

My sides are similar, i always just thought it was really aggressive balding.

 

[camille leprevost]

Hello my friend, i am french so i apologise in advance for my english.

I do have the same pattern as you, almost the same age 28, thinning and overall shedding back, side, and top and my hairline is quite not touched actually. I think it is DUPA and it is similar to female pattern hair loss actually.

Some studies showed that high prolactin level can cause hair on side and back to become sensitive to androgen as well. So might be something to dig in. Also annecdotally, it seems that DUPA sufferer are sensitive to DHT but also to Free testosterone in scalp. Apparently DHT seem to cause localised thinning where testosterone cause diffuse thinning.

So If you have been to a dermatologist, i hope she gave you a full bloodwork to do because besides that they are useless, and i am sure she didn't know what you had and told you it is some telogen effluvium, stress related stuff ....

You need to check for :
-nutritionnal defficiency
-metabolism glucidic ((Glucose, insuline sensitivity,)
- full hormonal check : cortisol, LH ,FSH ,Prolactine, E2,17OH progesterone, progesterone, SHBG, testosterone total, free T, androstanediol G6470, delta 4 androstenedione, DHEA-S, DHT ....
- inflamatory syndrom ...

I am going to do a full blood check this friday, so i will send you the result here in 2 weeks if you want. If you have done a full blood work too, it will be great to compare it to check for similitude.

To tell you a bit about myself i started to lose hair all over since 3 years now.
I only started 7 month ago to take 1 mg finasteride daily, but it has thin my hair considerably because of the boost of scalp tesoterone it caused i think. I tried to add different antiandrogen topically such as ru58841 to tackle the rise in T (had to stop due to chest pain , shortness of breath), i used now topical cb0301 30mg/day but it is not enough powerful so it doesn't do sh*t. I am going to try topical bicalutamide now soon as it is a stronger AA and i think we have to fight testoerone as well.
Besides finasteride + cb0301 i don't take any supplement and it didn't stop my shedding at all.

I am curious to know about how much you lose hair per day, what regimen are you on, it seems you use minoxidil, dit it worked on you ? and how you manage to apply it all over your head ?

Also @(Will Be an Egg in 5 years) and (@Paqua) can you share if anything in your regimen has improved your situation so far or make it worse. Would be great to share info

You can send me a message privately as well.

Looking forward helping each other to solve that sh*t.

Best regard

 

[camille leprevost]

Hello, just to recap, I am a man and have DUPA hair loss (or female pattern hair loss), diffuse hair loss and thinning (back, sides and top) which started 3 years ago after an episode in my life where my alimentation was very bad and had nutrient deficiency for sure. After fixing my alimentation properly my hair are still shedding and thinning all over.

Since 8 month i only take 1mg finasteride / day (no reduction on my hair loss), cb0301 30mg topicaly with no reduction on my hair loss, Biotin (10mg/day), spearmint tea (4 cup/day to reduce free testosterone), Flaxseed (30 g/day to reduce testosterone)

Here is a complete blood test that I have done 3 weeks ago. It would be great if some of you may highlight some issue in it and maybe propose corrective action as he might help others with similar hair loss.

From my perspective, I think I have low zinc, low vitamin d, high prolactin level, high cortisol level and maybe iron deficiency as we can have it according to study even with normal level of blood iron.

BLOOD TEST of the 04.12.2020

Vitamin B12 : 812 ng/l (197-771)
Vitamin A : 0.5 mg/l (0.1-1)

IONIC BALANCE

Sodium : 139 mmol/l (136-145)
Potassium : 4 mmol/l (3.5-4.5)

PROTEIN

Albumin : 47 g/l (40-49)

RENAL FUNCTION

Urea : 46 mg/dl (17-48)
Creatinine : 0.94 mg/dl ( 0.7-1.2)
DFG (CKD-EPI) >90 mL/min/1.73m^2

LIVER/PANCREAS

AST(GOT) : 16 UI/L (<40)
ALT(GPT) : 10 UI/L (<41)
alkaline phosphatase : 55 UI/L (40-129)
Gamma GT : 10 UI/L (10-71)
LDH : 178 UI/L (135-225)
Biribulin total : 0.8 mg/dl (<1.2)
Biribulin conjugated : 0.3 mg/dl (<0.2)

CARDIOVASCULAR RISK FACTOR

Triglyceride : 68 mg/dl (<150)

CARBOHYDRATE METABOLISM

Fasting glucose level : 96 mg/dl (70-100)
Insulin : 39.7 mg/dl (17.8-173)
Index HOMA1-IR : 1.4 pmol/l (<2.4)

TYROID

TSH : 1.35 mu/l (0.27-4.20)
T4 libre : 17.8 pmol/l (12-22)

ADRENAL GLAND

Cortisol (morning test) : 480 nmol/l (166-507)

CALCIUMPHOSPHATE METABOLISM

Bioactive PTH (3nd gen) 25.5 ng/l < 49
25 OH vitamin D : 14.8 μg/l (30-80)

ENDOCRINOLOGY

Total prolactin : 18.2 μg/l (4-15.2)
Bioactive prolactin : 14.9 μg/l (3-11.6)
LH : 5.8 UI/L (1.7-8.6)
FSH : 1.9 UI/L (1.5-12.4)
Oestradiol : 30 ng/l (25-52)
Progesterone : 0.24 μg/l < (0.15
17OH-Progesterone : 3 ng/ml (0.9-3.4)
total Testosterone : 20.80 nmol/l (8.64-29)
Testosterone free: 509.1 pmol/l (260-740)
Androstanediol glucoronide 2.8 nmol/l (4-75)
Delta 4 androstenedione : 1.4 ng/ml (0.1-3)
DHEA-S : 4.72 μmol/l (4.34 – 12.20)
SHBG : 24 nmol/l (18.3-54.1)
DHT : I don’t have the result yet

TOXICOLOGY

Zinc : 72 μg/dl (80-120)

BLOOD

Haemoglobin : 16.6 g/dl (13-18)
Red blood cell : 5.40 10^6/μl (4.40-5.90)
Hematocrit : 45.5% (40-53)
mean corpuscular volume : 84 fL (80-100)
mean corpuscular HB : 30.6 pg (26-34)
mean corpuscular haemoglobin concentration : 36.5 g/dl (31-35)
anisocytose indice : 12% (11.5-13.4)
platelet : 208 10^3/ μl (150- 440)
mean platelet volume : 10.1 fL (8.9-12.9)
white blood cell : 7.16 10^3/ μl (3.5-11)
neutrophiles : 62.1% (40-75)
neutrophiles (absolute): 4.44 10^3/ μl (1.5-6.7)
Lymphocytes : 25.4% (20-45)
Lymphocytes (absolute) : 1.82 10^3/ μl (1.2 – 3.5)
Monocytes : 10.6 % (2-10)
Monocytes (absolute) : 0.76 10^3/ μl (0.2 - 1)
Eosinophiles : 1.5% (2-10)
Eosinophiles (absolute) : 0.11 10^3/ μl (<0.4)
Basophiles : 0.4% (0-1)
Basophiles (absolute) : 0.03 10^3/ μl (<0.1)

INFLAMMATORY SYNDROM

Crp : <0.5 mg/dl (<5)

ANEMIA

Iron : 134 μg /dl (65-175)
Transferrin : 216 mg/dl (215 – 365)
Transferrin saturation : 44% (16-44)
Ferritin : 120 μg/l (30-300)
Folic acid : 4.8 μg/l (>4.6)
Folic acid erytrocytaire : 754 μg/l GR (523-1257)