Increased DHT levels in androgenic alopecia have been selected for to protect men fro

[shivers20]

Increased DHT in androgen alopecia to protect from prostate cancer

Increased DHT levels in androgenic alopecia have been selected for to protect men from prostate cancer.

Authors
Bhargava S.
Journal
Med Hypotheses. 2014 Jan 26. pii: S0306-9877(14)00027-9. doi: 10.1016/j.mehy.2014.01.016. [Epub ahead of print]

Affiliation
Abstract
Androgenic alopecia, a condition characterized by increased levels of DHT could have been selected for due to the benefits that prostaglandin D2 (PGD2) has on the prostate. A DHT metabolite can increase the transcription of prostaglandin D2 synthase through estrogen receptor beta. The increase of PGD2 can decrease the risk of prostate cancer and proliferation of prostate cancer cells. Therefore, the mechanisms behind male pattern baldness may also curtail the advancement of prostate cancer.

Copyright © 2014 Elsevier Ltd. All rights reserved.
PMID 24548754 [PubMed - as supplied by publisher]
Full text: Elsevier Science

 

[swingline747]

Increased DHT levels in androgenic alopecia have been selected for to protect men from prostate cancer.

Authors
Bhargava S.
Journal
Med Hypotheses. 2014 Jan 26. pii: S0306-9877(14)00027-9. doi: 10.1016/j.mehy.2014.01.016. [Epub ahead of print]

Affiliation
Abstract
Androgenic alopecia, a condition characterized by increased levels of DHT could have been selected for due to the benefits that prostaglandin D2 (PGD2) has on the prostate. A DHT metabolite can increase the transcription of prostaglandin D2 synthase through estrogen receptor beta. The increase of PGD2 can decrease the risk of prostate cancer and proliferation of prostate cancer cells. Therefore, the mechanisms behind male pattern baldness may also curtail the advancement of prostate cancer.

Copyright © 2014 Elsevier Ltd. All rights reserved.
PMID 24548754 [PubMed - as supplied by publisher]
Full text: Elsevier Science

My g paw was norwood 7 and had prostate cancer

 

[Sparky4444]

My g paw was norwood 7 and had prostate cancer

That doesn't matter...this rationale is something that at least tries to explain wtf men lose their hair and why male pattern baldness has evolved...this is along the same lines that some scientists hypothesize why homosexuality is a part of evolution -- this rationale goes that throughout the generations, some bloodlines actually need MORE female-orientated functionality to help better serve the bloodline...it's a fascinating study and very strongly rooted in observation...

...evolution allowed male pattern baldness to develop and indeed become very prevalent...this rationale could illustrate evolution doing it's part for the survival of the species...

 

[TheHandsomeLurker]

Increased DHT levels in androgenic alopecia have been selected for to protect men from prostate cancer.

Authors
Bhargava S.
Journal
Med Hypotheses. 2014 Jan 26. pii: S0306-9877(14)00027-9. doi: 10.1016/j.mehy.2014.01.016. [Epub ahead of print]

Affiliation
Abstract
Androgenic alopecia, a condition characterized by increased levels of DHT could have been selected for due to the benefits that prostaglandin D2 (PGD2) has on the prostate. A DHT metabolite can increase the transcription of prostaglandin D2 synthase through estrogen receptor beta. The increase of PGD2 can decrease the risk of prostate cancer and proliferation of prostate cancer cells. Therefore, the mechanisms behind male pattern baldness may also curtail the advancement of prostate cancer.

Copyright © 2014 Elsevier Ltd. All rights reserved.
PMID 24548754 [PubMed - as supplied by publisher]
Full text: Elsevier Science

This is pure speculation, as is acknowledged in the abstract.

What journal is this from?