in 20 years?

abcdefg

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Nothing in science is ever guaranteed. Mother nature dictates to us what we can and can not do. All we can do is try to push what we have as far as possible such as making maximum use of the elements we have and things like that. Its really pointless even guessing what might happen in terms of cures or what not.
 

Vanzzzz

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henryk9 said:
I think it is up to you how you define cure. Is it a cure when you just take one pill and that's it or a pill every day for the rest of your life? For me a cure is taking the stuff once (or over a period) and then it stops forever. The cure will be found for sure but it will be not released for us.

Considering how hair loss is purely cosmetic in nature, I will be more than willing to take an injection, apply a topical, pop a pill for the rest of my life. Applying topical or popping a pill is really not that much different from applying sun-screen or taking supplements.
 

peter079

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Applying topicals is a pain in the a$$. I'm applying some potion now, but I can't see myself doing it for the rest of my life.
 

cuebald

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If anyone other than perhaps Merck find a cure to baldness, why wouldn't they release it? Even if they would make money perpetually by selling finasteride, the first company to sell a cure would find itself very very rich indeed (at the expense of all the other firms still selling ye olde finasteride)

A cure would really be defined as a pill or injection you take once that stops you from ever going bald - well, perhaps that would more accurately be termed a "vaccine" than a "cure"...

A real cure I suppose would be a treatment that somehow regrew all of your hair, if you were NW6. Say you took a pill, and then your hair started growing as it did in your teen years - in a week it sprouted through the skin, in a month you had a nice centimetre or so of hair all over your head. I don't even think anything like that is possible, seeing as though the follicles are physically damaged (and it is your genetic programming causing this damage.)

I think male pattern baldness-damaged follicles would be the same as burn-damaged follicles (or follicles killed via Electrolysis) - only transplantation is going to get you new hairs. The higher hair count you see when using Minoxidil is simply Minoxidil making more hairs enter the anagen phase (it is not actually creating new follicles)
 

Boondock

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A real cure I suppose would be a treatment that somehow regrew all of your hair, if you were NW6. Say you took a pill, and then your hair started growing as it did in your teen years - in a week it sprouted through the skin, in a month you had a nice centimetre or so of hair all over your head. I don't even think anything like that is possible, seeing as though the follicles are physically damaged (and it is your genetic programming causing this damage.)

I'm sure you're aware already, but this is precisely what Histogen are proposing.

Their proposal is rooted in two questions:

1. When a newborn's hair begins to grow all over the scalp, what biological process initiates that?

2. Can we mimic that biological process?

They claim that they can, which - if correct - may indeed make what you term impossible, well, possible.

I'm not so confident in the short term myself, but it doesn't seem like such an impossibility to me.
 

kthxbi

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peter079 said:
Only way male pattern baldness will be cured is by eradicating the gene from society. I can't see this happening for a while. To do this it will most likely be in the form of immunization of children (both boys and girls carry the gene) to remove the gene until it no longer exists.

This will not be easy to monitor because firstly, parents are unwilling to get their children immunized against something new like this because of fear of side-effects, and secondly, it will only take one person to be left with the gene to re-infect the population.

Even if they find a way to cure male pattern baldness in grown men, like a vaccine, we still carry the gene and will most likely pass it onto our children.
the point youre missing is that curing is different to prevention. youre talking about preventing male pattern baldness whereas i believe the question was whether thered be a cure - ie something which gets rid of it once its been diagnosed.
interesting thread, but i really dont know enough about the subject to have much of an opinion other than 'i hope'
 

peter079

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I think Histogen must be looking into Stem Cell Research then. Stem cells are the cells that then go on to changing into all the other cells in the body.
We all start off as a few cells, that then divide and change into other cells like brain cells, lung cells, muscle, heart, etc, etc, and hair follicles. How one cell completely changes into another with a totally different function is what is most intriguing.

I read recently that a race horses developed a knee problem, so was no longer of any use. Ordinarily these horses are put down. But it was injected with stemcells into the knees and within weeks the knee repaired itself to how it used to be.

I also read that chinese scientists have developed a way to turn ordinary cells back into stemcells which can then turn into other cells. So stem cells may not need to be harvested from embryos.

It's still in early developement and more research needs to be done into how safe this is and side-effects etc.
 

Boondock

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peter079 said:
I think Histogen must be looking into Stem Cell Research then. Stem cells are the cells that then go on to changing into all the other cells in the body.
We all start off as a few cells, that then divide and change into other cells like brain cells, lung cells, muscle, heart, etc, etc, and hair follicles. How one cell completely changes into another with a totally different function is what is most intriguing.

I read recently that a race horses developed a knee problem, so was no longer of any use. Ordinarily these horses are put down. But it was injected with stemcells into the knees and within weeks the knee repaired itself to how it used to be.

I also read that chinese scientists have developed a way to turn ordinary cells back into stemcells which can then turn into other cells. So stem cells may not need to be harvested from embryos.

It's still in early developement and more research needs to be done into how safe this is and side-effects etc.

Well, yes. Sort of.

The full-blown stem cell method would be to use stem cells to create hair follicles in vitro, then to implant them into the scalp like a hair transplant.

Histogen are manipulating our body's own latent growth properties to try and grow hair again, by using a chemical formula which mimics that present in the baby's scalp when hair is first generated.

The suggestion is that even if this can't produce a full head of hair right away, it can allow the potential donor area of a transplant to become larger. I'm sceptical, but we will see. I'm a pretty hard-nosed bastard so the fact that I'm cautiously optimistic says something.
 

Vanzzzz

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Boondock said:
peter079 said:
I think Histogen must be looking into Stem Cell Research then. Stem cells are the cells that then go on to changing into all the other cells in the body.
We all start off as a few cells, that then divide and change into other cells like brain cells, lung cells, muscle, heart, etc, etc, and hair follicles. How one cell completely changes into another with a totally different function is what is most intriguing.

I read recently that a race horses developed a knee problem, so was no longer of any use. Ordinarily these horses are put down. But it was injected with stemcells into the knees and within weeks the knee repaired itself to how it used to be.

I also read that chinese scientists have developed a way to turn ordinary cells back into stemcells which can then turn into other cells. So stem cells may not need to be harvested from embryos.

It's still in early developement and more research needs to be done into how safe this is and side-effects etc.

Well, yes. Sort of.

The full-blown stem cell method would be to use stem cells to create hair follicles in vitro, then to implant them into the scalp like a hair transplant.

Histogen are manipulating our body's own latent growth properties to try and grow hair again, by using a chemical formula which mimics that present in the baby's scalp when hair is first generated.

The suggestion is that even if this can't produce a full head of hair right away, it can allow the potential donor area of a transplant to become larger. I'm sceptical, but we will see. I'm a pretty hard-nosed bastard so the fact that I'm cautiously optimistic says something.

I think your explanation is kinda off boon. What I think instead is that Histogen stimulates your follicles to start growing hair again, since DHT kinda makes them dormant, and not dead. Thus Histogen kinda reverses this effect. However, I do not see how this increases the donor area, as the regrown hair will still be susceptible to DHT attacks.
 

andrei_eremenko

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they say that it can create nwe follicles...becuase their forrmula stimulate this...i'm not so sceptical because is the time to something new to come on the market!
 

andrei_eremenko

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and I really think that our generation who's in their 20's will end up with a head full of hair one day...I don't know when...but hope sooner...
 

Boondock

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Vanzzzz said:
Boondock said:
peter079 said:
I think Histogen must be looking into Stem Cell Research then. Stem cells are the cells that then go on to changing into all the other cells in the body.
We all start off as a few cells, that then divide and change into other cells like brain cells, lung cells, muscle, heart, etc, etc, and hair follicles. How one cell completely changes into another with a totally different function is what is most intriguing.

I read recently that a race horses developed a knee problem, so was no longer of any use. Ordinarily these horses are put down. But it was injected with stemcells into the knees and within weeks the knee repaired itself to how it used to be.

I also read that chinese scientists have developed a way to turn ordinary cells back into stemcells which can then turn into other cells. So stem cells may not need to be harvested from embryos.

It's still in early developement and more research needs to be done into how safe this is and side-effects etc.

Well, yes. Sort of.

The full-blown stem cell method would be to use stem cells to create hair follicles in vitro, then to implant them into the scalp like a hair transplant.

Histogen are manipulating our body's own latent growth properties to try and grow hair again, by using a chemical formula which mimics that present in the baby's scalp when hair is first generated.

The suggestion is that even if this can't produce a full head of hair right away, it can allow the potential donor area of a transplant to become larger. I'm sceptical, but we will see. I'm a pretty hard-nosed bastard so the fact that I'm cautiously optimistic says something.

I think your explanation is kinda off boon. What I think instead is that Histogen stimulates your follicles to start growing hair again, since DHT kinda makes them dormant, and not dead. Thus Histogen kinda reverses this effect. However, I do not see how this increases the donor area, as the regrown hair will still be susceptible to DHT attacks.

False. Histogen's stated ambition is to be able to grow follicles from scratch in areas of the body that have latent capacity for this. The obvious application for this is to grow hair on bald areas. A secondary goal would be to grow more hair in the donor area (i.e. back of head), thus increasing the amount of transplantable hair for a procedure.

Whether they'll reach anywhere near these aims is another matter.
 

bigentries

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Haven't some cancer drugs in tests made bald people of advanced age not only grow their hair at pre-puberty line, but also returned their original coloring?
I think this is enough proof to stop believing that the follicles are damaged and can't never grow back

And about the usual conspiracy theories...
I guess the evil glasses industry stopped Lasik from becoming a reality, I mean, they would never let people have perfect vision for the rest of their lifes :jackit:
Also, I know Gillette is trying to stop this thing called laser hair removal because the ladies will never need to buy a razor anymore :jackit:

Christ, stop playing the victims
 

Vanzzzz

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I myself also believe that the follicles are not killed, but are rather in a dormant stage. Thus given the right stimulus, they can be encouraged to grow hair again. At least, I fervently hope this to be the case, so that EVERYONE, even those with severe balding, can benefit from any new revolutionary treatments for hairloss.
 

andrei_eremenko

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I think this is the histogen goal to grow back the hair...but...if this can grow back the hair why do we need to grow more hair at the donor area?
keep in mind that the results so far a great...from a single injection in one year something like 100 hairs has grown back in the balding/thinning area...and this is just a preliminary trail...
 
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