If topical minoxidil (aplied to scalp) doesn't go systemic why so many people get skin sides on topical minoxidil

Hairstani

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There are a lot of anecdotal claims of signs of collagen breakdown after using topical minoxidil. If topical min doesn't go systemic, why so many users experience sides?
 

blue16

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Self selecting sample of people here on the forums have side effects. The people that take it and don't notice any sides disappear and move on.
 
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