Pine bark extract boost for blood flow and heart health
By Stephen Daniells
10/18/2007 - Extracts from French maritime pine bark may boost the body's production of nitric oxide - key to better blood flow and oxygen supply to muscles - suggests a new study.
The results of the new study, published in the October issue of the journal Hypertension Research, add to a growing body of research reporting potential health benefits of the pine bark extract, Pycnogenol.
"This study suggests that when taking Pycnogenol, more NO is provided in response to neurotransmitters allowing for better expansion of arteries to carry more blood. This process serves to meet the enhanced oxygen demand of the performing muscle and avoid anaerobic metabolism," said lead researcher Dr. Yukihito Higashi from the Hiroshima University Graduate School of Biomedical Sciences in Japan.
Nitric oxide (NO) is a molecule used by the endothelium (cells lining the surface of blood vessels) to signal surrounding muscle to relax, leading to a reduction in blood pressure, reduced blood clotting and protection against myocardial infarction and strokes.
The researchers performed a double-blind, randomized, placebo study with 16 young, healthy men receiving either a daily pine bark extract (180 mg Pycnogenol) or placebo for two weeks. In order to identify the role of the extract on NO, the subjects were also infused with an inhibitor of the amino acid L-arginine was infused in patients, thereby causing a constriction of the arteries in response to the neurotransmitter acetylcholine.
After two weeks of intervention, supplementation Higashi and co-workers report that supplementation with the French maritime pine bark extracts was associated with a 42 per cent stimulation of blood flow after infusion of the inhibitor. No significant changes in blood flow was observed in the placebo group.....
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