How does oral min compare to liquid foam versions

dekaz

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i didn't know there was an oral minoxidil :S i would stick to the topical liquid simply because it stimulates dormant folicles to grow hair where you apply it, i dont see how oral min could do that unless it made every folicle in your body grow hair and turn you into chewbacca =|
 

psyhotria

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If you wanna know, you will have to do the test. Now, while 1 loniten tab contains up to 10mg minoxidil, 1ml of standard minoxidil solution contains 50mg of minoxidil.. and you can perfectly drink the minoxidil solution; but be careful with drinking minoxidil, for too much of it could do serious damage..
 

zdm632

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If you wanna know, you will have to do the test. Now, while 1 loniten tab contains up to 10mg minoxidil, 1ml of standard minoxidil solution contains 50mg of minoxidil.. and you can perfectly drink the minoxidil solution; but be careful with drinking minoxidil, for too much of it could do serious damage..

Yes, topical contains more, but very little of that 50 mg gets to the follicle, really.
Yes, oral version stimulates hair on the entire body, it makes it a bit thicker, but no, it doesn;'t turn you into a hairy gorilla. :lol:
And yes, oral version is much powerful, it gets straight to the follicle via blood, topical min has to travel 4 mm deep inside the skin, to get to the follicle.
And anyway, i am not a medical expert,but it may be that even the topical minoxidil works mainly because the very little amount that gets into bloodtsream.

Imo, from experience, topical minoxidil is a weak treatment, i believe most people just have poor epidermic aborbtion of it. Think about, for example the persons with very oily scalp. How can minoxidil go down the follicle shaft when the sebaceous gland throws oil out?
Maybe it can work right after the shower, but by the second day, at the 3-4 th application i think the absorbtion is almost zero.
Oral one is many times much powerful, but there are some risks:it lowers blood pressure, so if you already have blood pressure, you can't take it. But if you're slightly hipertensive, you may be able to take it.

Ithink topical minoxidil is just not worth it, thinking about the hassle to apply twice a day, the results are just poor, in the majority of people.
There is dr Pathomvanich, who gave oral loniten to his patients, and almost all of them got consistent thickening, much more than they had with topical version. And the fact that, when some of them switched from oral back to topical, the results did not maintain at all, says everything about the difference between oral and topical effectiveness.
And, on top of that, topical min contains alcohol and propylene-glycol, which are not so good to the hair and scalp.
To sum it up, oral is much powerful, but most people are just scared to take it, because it has somehow the reputation of a dangerous drug. Yes, it is dangerous, but not at the small doses for hairloss such as 5 mg.
You can try it and stop if you have sides, it won't kill anyone at 5 mg/daily.
 

massa

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Oral is better as you're more likely to get a consistent dose as it's easy to take a pill . With topical lots of the liquid or foam gets clogged up by hair and never actually reaches the follicle . Topical minoxidil is a no go for someone who has long thinning hair , if you buzz your hair to a 1 or 2 you may get better absorption but if you actually want a hairstyle it doesn't work . The only down side to oral is it grows body hair where you may not want it but the only place I have noticed an increase of body hair is my upper arms and my forehead but even then it's not so bad . 5mg or even 10mg is actually a low safe dose for most people . But probably get your blood pressure checked beforehand .
 

resu

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I apply with a syringe, it doesn't get wasted in the hairs.
 

resu

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as in you inject it subcutaneously? or just very close to the scalp

I use this type and apply it right in the scalp then spread a little with the fingers so it doesn't run to the sides. They won't pierce the skin and you can apply it very comfortably.

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resu

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I doubt that, why would they even bother making the foam version 10 years later or so? Just make a dose adequate pill for hair loss.
 

zdm632

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I doubt that, why would they even bother making the foam version 10 years later or so? Just make a dose adequate pill for hair loss.

What do you doubt? That oral form is much more effective than topical?
.
 

resu

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That it's more effective and if dosed to just target Androgenetic Alopecia it wouldn't have sides. Either way one or the other has to be true otherwise they wouldn't bother with the foam.
 

zdm632

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That it's more effective and if dosed to just target Androgenetic Alopecia it wouldn't have sides. Either way one or the other has to be true otherwise they wouldn't bother with the foam.
As i know their motivation for introducing the topical instead of oral is:
-more safety(imo they didn't want to risk messing with blood pressure)
-the fact that some people would not like the thickening of the body hair.

The fact is that, first, the had only oral version for blood pressure, and hair growth was a side effect.
They tried the topical and...got results with it, but the results with topical are way weaker.

It was the same with finasteride:developed for other condition, side effect of growing more hair. If i remember well, they tried with topical even with finasteride, but it just didn't work at all, or very little.

Maybe, if the topical minoxidil wouldn't work to some extent, they would made a minoxidil pill, at a smaller dose, just like with finasteride.

Yes, topical minoxidil works, but oral one works way better, only for the small minority who have balls to get on it.
And, as i said before, i think some peple's skin may just be a very poor absorber of topicals, that's why topical minoxidil performs very poor on them.
 

psyhotria

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-the fact that some people would not like the thickening of the body hair.
True - oral minoxidil is certainly more effective at pushing body hair; though unlikely scalp hair. Because topical minoxidil is pouring into the system for 24h and more, saturating in the scalp and constantly supplying the hair organs. Now, if one does not know how to effectively apply to scalp - this is a different problem. Also I was suggesting that in the case someone would want to go the oral route, taking the minoxidl solution internally is a lot more economic than the tabs - first you get a lot more minoxidil for the buck and second you (likely) do not need a prescription.
 

zdm632

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True - oral minoxidil is certainly more effective at pushing body hair; though unlikely scalp hair. Because topical minoxidil is pouring into the system for 24h and more, saturating in the scalp and constantly supplying the hair organs. Now, if one does not know how to effectively apply to scalp - this is a different problem. Also I was suggesting that in the case someone would want to go the oral route, taking the minoxidl solution internally is a lot more economic than the tabs - first you get a lot more minoxidil for the buck and second you (likely) do not need a prescription.

No, taking solution internally is a bad idea, it also contains alcohol and propylene glycol.

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though unlikely scalp hair. Because topical minoxidil is pouring into the system for 24h and more, saturating in the scalp and constantly supplying the hair organs.

I don't think so, it just dries on the hair/scalp after some time. There is constantly the flow of sebum getting out the hair follcile, so i doubt about the absorption after a couple of hours after application.
What you say makes no sense, so it thickens the body hair, but "unlikely" scalp hair. Scalp hair is not on the body, or what?
 

resu

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A lot of people have gotten good results with topical minoxidil alone, it can't be that useless. Show me any example of someone that has gotten great results from low doses of oral minoxidil, specially someone who didn't get good results topically.

Minoxidil just isn't a miracle, if it doesn't work for you topically it won't work taken orally either.
 

psyhotria

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No, taking solution internally is a bad idea, it also contains alcohol and propylene glycol.
People are drinking alcohol by the tons (it is ethyl alcohol btw) - we are talking sub 1 ml values here lol. And PG is a humectant that is used in (commercial) food preparation - but again we are talking sub 1 ml values here. So it is perfectly fine and very cheap to "drink" minoxidil solution.
What you say makes no sense, so it thickens the body hair, but "unlikely" scalp hair. Scalp hair is not on the body, or what?
It makes very well sense: topical minoxidil is less going systemically but more to the follice. Thus body hair will benefit disproportionately from oral minoxidil while the fillicles will do the other way around. And no, minoxidil does not just dry outside, there are penetration studies done with different vehicles which show effectiveness of delivery.
 

zdm632

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People are drinking alcohol by the tons (it is ethyl alcohol btw) - we are talking sub 1 ml values here lol. And PG is a humectant that is used in (commercial) food preparation - but again we are talking sub 1 ml values here. So it is perfectly fine and very cheap to "drink" minoxidil solution. It makes very well sense: topical minoxidil is less going systemically but more to the follice. Thus body hair will benefit disproportionately from oral minoxidil while the fillicles will do the other way around. And no, minoxidil does not just dry outside, there are penetration studies done with different vehicles which show effectiveness of delivery.

And how do you know that PPG in minoxidil solution is the same as that used in foods, and not industrial type, which may include contaminants.
The same with alcohol, it is syntetic lab-produced alcohol, not alcohol distiiled from plants/grains, like the one you drink.

And you talk like scalp follicles are somehow detached from the body?!
Oral minoxidil gets to the hair follicles the same as it gets to body hair follicles, via blood flow.
minoxidil doesn't ALL dry outside, but a good portion of it, then how do you explain the residue left on scalp, which is really annoying.
I'm not trying to say that topical minoxidil is useless, but oral one is much stronger.

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Minoxidil just isn't a miracle, if it doesn't work for you topically it won't work taken orally either.

Actually some hair transplant doctor called dr Pathomvanich contradicts this. He had patients who didn't respond to topical but responded very well to oral. To the point that a previous non-candidate for a hair transplant due to too much baldness became a candidate after 4 months.
Source: https://books.google.ro/books?id=vd...page&q=dr pathomvanich oral minoxidil&f=false
 

resu

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Asians do respond better for some reason. Even so I wouldn't gamble for a few more hairs.
 

forestlawn

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Its just a lazy mans rogaine but it has more potential to cause unwanted hair growth. So unless you like bushy nose and ear hair, I'd go the foam way
 
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