Hi all, Ive reently been through a trial of minoxidil and proprecia with moderate success and purchased a bottle of 5% spironolactone cream to use in combo. I have heard that spironolactone is dangerous to take orally for men but how bad is it topically in cream form? What are the experiences from people who have used it- has it lowered your testosterone or decreased your testicle size?
How dangerous is topical spirolactone?
- Thread starter drew100
- Start date
maximiliandreams
Established Member
- Reaction score
- 1
You will not find a more potent antiandrogen (without ANY side effects) on the market anywhere. Topical Spironolactone has become one of our most popular products, and for good reason. It is safe and effective for use in both men and women with thinning hair, and can be used in conjunction with Propecia (men only) to topically enhance the effects.
This product is one of the "Big Guns" for both men and women. There are several antiandrogens which are taken orally that could cure hair loss. The problem is, some of them will also wreak havoc on your hormone system.
Generic Finasteride (Propecia) for men only, is the most tolerated of all the orally ingested antiandrogens, and it does a phenomenal job at stopping further hair loss. It is one of the "Big Three" (a phrase coined for Propecia, Rogaine, and Nizoral Shampoo) that many of our users live and breathe by. Spironolactone works for many women orally, but is not an option for men due to feminizing effects.
However, a topically applied, locally working version of Spironolactone would seem like a complete dream. So here it is. This powerful antiandrogen will only absorb locally. This not only doubles the effect of your Propecia regimen, but it adds absolutely no side effects to the equation. Topical Spironolactone absorbs only into the scalp skin, and locally stops the formation of DHT, as well as blocks androgen receptors in the follicle. This product is a perfect complement to a Propecia or Revivogen regimen.
IT's not dangerous.
This product is one of the "Big Guns" for both men and women. There are several antiandrogens which are taken orally that could cure hair loss. The problem is, some of them will also wreak havoc on your hormone system.
Generic Finasteride (Propecia) for men only, is the most tolerated of all the orally ingested antiandrogens, and it does a phenomenal job at stopping further hair loss. It is one of the "Big Three" (a phrase coined for Propecia, Rogaine, and Nizoral Shampoo) that many of our users live and breathe by. Spironolactone works for many women orally, but is not an option for men due to feminizing effects.
However, a topically applied, locally working version of Spironolactone would seem like a complete dream. So here it is. This powerful antiandrogen will only absorb locally. This not only doubles the effect of your Propecia regimen, but it adds absolutely no side effects to the equation. Topical Spironolactone absorbs only into the scalp skin, and locally stops the formation of DHT, as well as blocks androgen receptors in the follicle. This product is a perfect complement to a Propecia or Revivogen regimen.
IT's not dangerous.
Einstein
Established Member
- Reaction score
- 110
Isn't it more than just a DHT blocker? Isn't topical spironolactone an anti-androgen in the sense that it block both dht and test?
How does applying spironolactone topically enhance finasteride's effectiveness? I wasn't aware they work synergistically.
How does applying spironolactone topically enhance finasteride's effectiveness? I wasn't aware they work synergistically.
- Reaction score
- 43
Einstein said:
It's for EXACTLY that reason that I strongly recommend that people use the same medical terms that doctors and scientists use: TO AVOID MAJOR CONFUSION! The term "DHT blocker" is meaningless and infuriating. It's a VERY bad choice of words!
To refer to something that binds to 5a-reductase and prevents it from converting testosterone into DHT, use the term 5a-reductase inhibitor.
To refer to something that binds to androgen receptors and prevents androgens from doing their normal job, use the term antiandrogen, or androgen receptor blocker.
By the way, I've seen conflicting information that spironolactone is a 5a-reductase inhibitor. I saw one study that claimed that it IS such an inhibitor, and another study that claimed that it ISN'T. You be the judge!
spironolactone is definitely an antiandrogen, though.
maximiliandreams
Established Member
- Reaction score
- 1
lol,Bryan...click on "get your treatments" and then click on S5 cream.. i copy/paste it from there.
Lets say you buy topical spironolactone and the manufacturer ships you some. What is the standard formulation for it and was that formulation tested that it actually works when you throw different amounts of ingredients together like that? The problem a lot of these have is it seems different manufacturers have different formulations with no real proof any of them actually work. Not to mention they are all really expensive. That is why an FDA or some approved topical is so important to have so we can stop guessing and start knowing.
Hey everyone, I'm new on here.
I ordered some of the S5 cream in somewhat of a haste, kind of taking the description on the ordering page at face value, but since then I've become kind of worried about the conflicting information I've seen...some people say it's super safe, some people say otherwise, that there's a strong chance that it actually gets systemically absorbed.
The way I see it, I don't have any problem trying it for a little while, and if my pecs start feeling tender and my balls start hurting, or I start getting an irregular heartbeat or something (yikes!), then I'll simply drop the stuff like a brick.
Here are the main concerns, though, which I am worried about--whatever you believe is actually the case, just suppose for a moment that some of the topical spironolactone actually gets absorbed into the bloodstream (or suppose, if it's easier for you, that I'm literally just swallowing some of the stuff, even though I don't plan on doing that):
-What are the chances that I could experience adverse effects such as lowered testosterone without consciously perceiving any symptoms?
-What are the chances that I could do any permanent damage to my body (i.e., that won't simply go away if I never touch spironolactone again), particularly in the way of: inability to produce as much testosterone/reduced libido/inability to attain an erection/other sexual side effects, etc., whether or not I perceive the side effects immediately/along the way (could they be chronic)?
If you have any sources on this, that would be awesome.
I ordered some of the S5 cream in somewhat of a haste, kind of taking the description on the ordering page at face value, but since then I've become kind of worried about the conflicting information I've seen...some people say it's super safe, some people say otherwise, that there's a strong chance that it actually gets systemically absorbed.
The way I see it, I don't have any problem trying it for a little while, and if my pecs start feeling tender and my balls start hurting, or I start getting an irregular heartbeat or something (yikes!), then I'll simply drop the stuff like a brick.
Here are the main concerns, though, which I am worried about--whatever you believe is actually the case, just suppose for a moment that some of the topical spironolactone actually gets absorbed into the bloodstream (or suppose, if it's easier for you, that I'm literally just swallowing some of the stuff, even though I don't plan on doing that):
-What are the chances that I could experience adverse effects such as lowered testosterone without consciously perceiving any symptoms?
-What are the chances that I could do any permanent damage to my body (i.e., that won't simply go away if I never touch spironolactone again), particularly in the way of: inability to produce as much testosterone/reduced libido/inability to attain an erection/other sexual side effects, etc., whether or not I perceive the side effects immediately/along the way (could they be chronic)?
If you have any sources on this, that would be awesome.