High DHT vs genetics in hairloss

hair_nag

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My understanding has been that male pattern baldness is mostly due to genetic predisposition of androgen receptors to DHT.


The question here is, would a guy with good non male pattern baldness hair genes also lose hair if enough DHT was given to him artificially? Or would such a guy never lose hair no matter how much DHT was injected into him?

I know I have male pattern baldness, but I do find it odd that my hair and facial skin were pretty much perfect until second half of 26, then suddenly I started having oily and inflamed skin on my forehead and started losing hair, while gaining significantly more body hair. Did my genetics just kick in at that time or was my DHT level suddenly elevated and my androgen receptors couldn't cope with it?
 

KiNGTyreZe

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My understanding has been that male pattern baldness is mostly due to genetic predisposition of androgen receptors to DHT.


The question here is, would a guy with good non male pattern baldness hair genes also lose hair if enough DHT was given to him artificially? Or would such a guy never lose hair no matter how much DHT was injected into him?

I know I have male pattern baldness, but I do find it odd that my hair and facial skin were pretty much perfect until second half of 26, then suddenly I started having oily and inflamed skin on my forehead and started losing hair, while gaining significantly more body hair. Did my genetics just kick in at that time or was my DHT level suddenly elevated and my androgen receptors couldn't cope with it?

Your DHT level probably suddenly elevated. Some people get their first mustache with 30.

However I think a guy would lose an amount of hair if you give him enough DHT.
For example: You see people having a girl hairline (which is round) before puberty.
They hit puberty and the girl hairline disappears. I've rarely seen anybody who kept his girl hairline.

So my conclusion is (even though some broscience) that if you inject somebody enough DHT it will damage his hair.
Some people have hair follicles who are just very resistent against DHT but you can even break those (extra injection), even if not in the natural way.
 

hair_nag

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Your DHT level probably suddenly elevated. Some people get their first mustache with 30.

However I think a guy would lose an amount of hair if you give him enough DHT.
For example: You see people having a girl hairline (which is round) before puberty.
They hit puberty and the girl hairline disappears. I've rarely seen anybody who kept his girl hairline.

So my conclusion is (even though some broscience) that if you inject somebody enough DHT it will damage his hair.
Some people have hair follicles who are just very resistent against DHT but you can even break those (extra injection), even if not in the natural way.

I figured the same. I did have a round hairline before puberty as well, after that I had the regular NW1 male hairline up to the middle of 26.
I have a fraternal twin who hasn't lost any hair beyond NW1, but this twin also has a lot less body hair and sparser beard. so I don't know if he just has different hair genetics or a lower DHT level.
 

g.i joey

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I figured the same. I did have a round hairline before puberty as well, after that I had the regular NW1 male hairline up to the middle of 26.
I have a fraternal twin who hasn't lost any hair beyond NW1, but this twin also has a lot less body hair and sparser beard. so I don't know if he just has different hair genetics or a lower DHT level.

Hellouser claims everyone has similar dht levels it's the sensitivity in our follicles that vary from person to person... imo makes the most sense, cause If that wasn't true I don't c how anyone would get sides from finasteride
 

hair_nag

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Hellouser claims everyone has similar dht levels it's the sensitivity in our follicles that vary from person to person... imo makes the most sense, cause If that wasn't true I don't c how anyone would get sides from finasteride

If that is true why does this site claim men have a wide range when it comes to DHT level? (250-990 pg/ml)!

http://www.hemingways.org/GIDinfo/hrt_ref.htm


Of course I m not saying follicular sensitivity isn't the main culprit of male pattern baldness, I just wonder if elevated DHT can also cause balding in a relatively short time.
 

zzzzz

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saying that no men are sensitive to DHT at least to some extent would be to say that some men aren't born with androgen receptors
 

xRedStaRx

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All hair is sensitive to DHT.

Genetically androgenic hair have higher levels of DHT inside their tissue.

People with no male pattern baldness, have little intrafollicular DHT.
 

abcdefg

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All hair is sensitive to DHT.

Genetically androgenic hair have higher levels of DHT inside their tissue.

People with no male pattern baldness, have little intrafollicular DHT.

Yeah this might be. I think all men would go bald if given enough DHT and most men that are Norwood 1 at 40+ years old generally have unusually small amounts of androgens for their age, and of course genes/poorly understood sensitivity factors in their favor too.
Doesnt much change the fact that you need to stop androgens to keep your hair for now atleast. PGD 2 and other things could change that down the road though
 

abcdefg

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I figured the same. I did have a round hairline before puberty as well, after that I had the regular NW1 male hairline up to the middle of 26.
I have a fraternal twin who hasn't lost any hair beyond NW1, but this twin also has a lot less body hair and sparser beard. so I don't know if he just has different hair genetics or a lower DHT level.

I would say he has lower androgen levels than you do because I do think androgens hurt hair in almost everyone over time. The more you have the worse your chances long term. MOST guys at older ages with Norwood 1 still have unusually little facial hair/body hair and I think that is why they keep their head hair just not much androgens over the years to harm it. Sensitivity is of course big but not much known on that.
 

Aesthetic

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I would say he has lower androgen levels than you do because I do think androgens hurt hair in almost everyone over time. The more you have the worse your chances long term. MOST guys at older ages with Norwood 1 still have unusually little facial hair/body hair and I think that is why they keep their head hair just not much androgens over the years to harm it. Sensitivity is of course big but not much known on that.

i have to agree with this, its very rare to find a man with nw1 and a GREAT beard, most nw1's past puberty can hardly grow and facial hair.

if your a nw1 and full thick bard ur in the top 10% of men in terms of blessed genetics
 

hair_nag

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i have to agree with this, its very rare to find a man with nw1 and a GREAT beard, most nw1's past puberty can hardly grow and facial hair.

if your a nw1 and full thick bard ur in the top 10% of men in terms of blessed genetics

What about Sean Bean? the dude is 56, full head of hair and a full beard!
 

SayifDoit

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Isn't it true that native americans do not suffer from male pattern baldness?
I think that is total bull regarding men growing proper beards while being a NW1, african american, middle eastern people, not forgetting hispanic individuals can grow superb beards in their late teens. And a good majority you don't see balding untill their 50's, especially the hispanics.
 

Aesthetic

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Isn't it true that native americans do not suffer from male pattern baldness?
I think that is total bull regarding men growing proper beards while being a NW1, african american, middle eastern peoplhe, not forgetting hispanic individuals can grow superb beards in their late teens. And a good majority you don't see balding untill their 50's, especially the hispanics.
yeah true, but we're kinda talking about white men i guess for the sake of the OP,
 

abcdefg

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The key has always been sensitivity to androgens I mean if you used something to completely prevent all androgens from interacting with hair then you would never bald regardless of androgen levels. Genes might play a large role in that hence some men with beards or whatever that at old age never lose hair. Its not black and white and a lot of it still is pretty poorly understood. Lots of people in different geographic areas generally have different gene pools so that might why large populations have different male pattern baldness characteristics.
 

Ventures

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people with a lot of body hair and zero male pattern baldness might have high DHT activity in parts of body with body hair but very low DHT actvity in scalp. Or they might have low AR sensitivity of scalp hair, so it doesn't matter if they have low or increased levels of DHT in scalp.
 

idunnolol

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Different parts of your body will reacat differently when exposed to DHT. If all the androgen receptors in your skin would react equally, you would look like the missing link when hitting puberty. There's no contradiction in balding at a young age but not being able to grow body hair anywhere expcept maybe your pubes. Likewise, it's possible to keep a juvenile hairline forever but still be as hairy as it can get.
If you look at the grand scheme of things though, hairy people are more likely to go bald statistically speaking.
 

hmm

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Isn't it true that native americans do not suffer from male pattern baldness?
I think that is total bull regarding men growing proper beards while being a NW1, african american, middle eastern people, not forgetting hispanic individuals can grow superb beards in their late teens. And a good majority you don't see balding untill their 50's, especially the hispanics.

I see a ton of bald black people much younger than 50. You just don't notice it as much because of their darker skin tone which also helps them pull off the shaved looked. If they don't keep it clean shaven you start to see the tennis ball shadow. Unfortunately for white men you see the shadow even after a clean shave because of the contrast. Same principle of several concealers which paint the scalp reducing contrast. They just have a naturally painted scalp I guess lucky them, balding and white is much harder to hide lol.
 
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