Has anyone tried PTD-DBM products to reverse hair loss through WNT signal?

[tryringtomaintain]

I've seen a couple of these products circulating, which is a WNT-inhibitor called PTD-DBM. Has anyone tried it and had success? I've bought 2 months worth so far but haven't had any results that I can tell. One company that sells it is Fountain Serum.


Products – FOUNTAIN (fountainserums.com)

???

 

[Seuxin]

It's sh*t.
I know severals guys tried...No effects . 0 !

 

[Janks16]

There's tons of this crap that guys buy and never get a singe hair from this stuff. It's all over Facebook. What a waste.

 

[Seuxin]

Wnt pathway seems to be a fail ! SM failed, Way316606 same, KY19382 same....

 

[tryringtomaintain]

thanks everyone!

 

[Redgate]

I've seen a couple of these products circulating, which is a WNT-inhibitor called PTD-DBM. Has anyone tried it and had success? I've bought 2 months worth so far but haven't had any results that I can tell. One company that sells it is Fountain Serum.

PTD-DBM is a WNT agonist, not an inhibitor (hair benefits come from activating the WNT). It needs to be injected to reach the follicle, so topical solutions don't work

here's a QRD on other WNT compounds that have been tried on the forum:
KY19382 is basically impossible to dissolve unless you make low dose solutions (like 0.01%) which don't work. We need to wait for trials to find out what vehicle they use. It has the same mechanism as PTD-DBM.
WAY-316606 "works" by inhibiting SFPR1 (it's inhibitior upregulates WNT) but it's dogshit. Max 5% improvement and the company that was pursuing it dropped it for that reason
Cyclosporine A has the same mechanism as WAY but it's more potent. It also targets several other things and there was a group buy recently (too early for results but it doesn't look as promising as initially thought)
It's also a powerful immunosuppressant that can cause skin cancer among other things

 

[Trichosan]

Tried it for 9 months. Nothing.

 

[Joxy]

Don’t waste your money and time on these kind of products.

 

[Seuxin]

Tried it for 9 months. Nothing.

oO god so it cost you a lot ? How did you used it ? You buy a topical product containing the peptide or you injected it subcutaneous ?

 

[Trichosan]

oO god so it cost you a lot ? How did you used it ? You buy a topical product containing the peptide or you injected it subcutaneous ?

Topical spray. About $54/month applied daily and after microneedling once a month.

 

[Seuxin]

Tried it for 9 months. Nothing.

PTD-DBM has a molecular weight at 3082.62, very high. It has to be injected or maybe using a bit of DMSO. Dermaroller once a week wont be enough to reach follicle.